scispace - formally typeset
Search or ask a question
Institution

University of Guelph

EducationGuelph, Ontario, Canada
About: University of Guelph is a education organization based out in Guelph, Ontario, Canada. It is known for research contribution in the topics: Population & Poison control. The organization has 26542 authors who have published 50553 publications receiving 1715255 citations. The organization is also known as: U of G & Guelph University.


Papers
More filters
Journal ArticleDOI
TL;DR: It is established that the mitochondrial gene cytochrome c oxidase I (COI) can serve as the core of a global bioidentification system for animals and will provide a reliable, cost–effective and accessible solution to the current problem of species identification.
Abstract: Although much biological research depends upon species diagnoses, taxonomic expertise is collapsing. We are convinced that the sole prospect for a sustainable identification capability lies in the construction of systems that employ DNA sequences as taxon 'barcodes'. We establish that the mitochondrial gene cytochrome c oxidase I (COI) can serve as the core of a global bioidentification system for animals. First, we demonstrate that COI profiles, derived from the low-density sampling of higher taxonomic categories, ordinarily assign newly analysed taxa to the appropriate phylum or order. Second, we demonstrate that species-level assignments can be obtained by creating comprehensive COI profiles. A model COI profile, based upon the analysis of a single individual from each of 200 closely allied species of lepidopterans, was 100% successful in correctly identifying subsequent specimens. When fully developed, a COI identification system will provide a reliable, cost-effective and accessible solution to the current problem of species identification. Its assembly will also generate important new insights into the diversification of life and the rules of molecular evolution.

9,879 citations

Journal ArticleDOI
Curtis Huttenhower1, Curtis Huttenhower2, Dirk Gevers2, Rob Knight3  +250 moreInstitutions (42)
14 Jun 2012-Nature
TL;DR: The Human Microbiome Project Consortium reported the first results of their analysis of microbial communities from distinct, clinically relevant body habitats in a human cohort; the insights into the microbial communities of a healthy population lay foundations for future exploration of the epidemiology, ecology and translational applications of the human microbiome as discussed by the authors.
Abstract: The Human Microbiome Project Consortium reports the first results of their analysis of microbial communities from distinct, clinically relevant body habitats in a human cohort; the insights into the microbial communities of a healthy population lay foundations for future exploration of the epidemiology, ecology and translational applications of the human microbiome.

8,410 citations

Journal ArticleDOI
TL;DR: In this article, a review of adaptation of human communities to global changes, especially climate change, in the context of adaptive capacity and vulnerability is presented, focusing on scholarship that contributes to practical implementation of adaptations at the community scale.
Abstract: This paper reviews the concept of adaptation of human communities to global changes, especially climate change, in the context of adaptive capacity and vulnerability. It focuses on scholarship that contributes to practical implementation of adaptations at the community scale. In numerous social science fields, adaptations are considered as responses to risks associated with the interaction of environmental hazards and human vulnerability or adaptive capacity. In the climate change field, adaptation analyses have been undertaken for several distinct purposes. Impact assessments assume adaptations to estimate damages to longer term climate scenarios with and without adjustments. Evaluations of specified adaptation options aim to identify preferred measures. Vulnerability indices seek to provide relative vulnerability scores for countries, regions or communities. The main purpose of participatory vulnerability assessments is to identify adaptation strategies that are feasible and practical in communities. The distinctive features of adaptation analyses with this purpose are outlined, and common elements of this approach are described. Practical adaptation initiatives tend to focus on risks that are already problematic, climate is considered together with other environmental and social stresses, and adaptations are mostly integrated or mainstreamed into other resource management, disaster preparedness and sustainable development programs. r 2006 Elsevier Ltd. All rights reserved.

4,612 citations

Journal ArticleDOI
TL;DR: In this article, the basic relationships are discussed in the context of vertical transfer in the lower atmosphere, and the required corrections to the measured flux are derived, where the correction to measurements of water vapour flux will often be only a few per cent but will sometimes exceed 10 percent.
Abstract: When the atmospheric turbulent flux of a minor constituent such as CO2 (or of water vapour as a special case) is measured by either the eddy covariance or the mean gradient technique, account may need to be taken of variations of the constituent's density due to the presence of a flux of heat and/or water vapour. In this paper the basic relationships are discussed in the context of vertical transfer in the lower atmosphere, and the required corrections to the measured flux are derived. If the measurement involves sensing of the fluctuations or mean gradient of the constituent's mixing ratio relative to the dry air component, then no correction is required; while with sensing of the constituent's specific mass content relative to the total moist air, a correction arising from the water vapour flux only is required. Correspondingly, if in mean gradient measurements the constituent's density is measured in air from different heights which has been pre-dried and brought to a common temperature, then again no correction is required; while if the original (moist) air itself is brought to a common temperature, then only a correction arising from the water vapour flux is required. If the constituent's density fluctuations or mean gradients are measured directly in the air in situ, then corrections arising from both heat and water vapour fluxes are required. These corrections will often be very important. That due to the heat flux is about five times as great as that due to an equal latent heat (water vapour) flux. In CO2 flux measurements the magnitude of the correction will commonly exceed that of the flux itself. The correction to measurements of water vapour flux will often be only a few per cent but will sometimes exceed 10 per cent.

4,174 citations

Journal ArticleDOI
TL;DR: It is indicated that sequence divergences at COI regularly enable the discrimination of closely allied species in all animal phyla except the Cnidaria and constraints on intraspecific mitochondrial DNA divergence arising through selective sweeps mediated via interactions with the nuclear genome.
Abstract: With millions of species and their life-stage transformations, the animal kingdom provides a challenging target for taxonomy. Recent work has suggested that a DNA-based identification system, founded on the mitochondrial gene, cytochrome c oxidase subunit 1 (COI), can aid the resolution of this diversity. While past work has validated the ability of COI sequences to diagnose species in certain taxonomic groups, the present study extends these analyses across the animal kingdom. The results indicate that sequence divergences at COI regularly enable the discrimination of closely allied species in all animal phyla except the Cnidaria. This success in species diagnosis reflects both the high rates of sequence change at COI in most animal groups and constraints on intraspecific mitochondrial DNA divergence arising, at least in part, through selective sweeps mediated via interactions with the nuclear genome.

4,071 citations


Authors

Showing all 26778 results

NameH-indexPapersCitations
Dirk Inzé14964774468
Norbert Perrimon13861073505
Bobby Samir Acharya1331121100545
Eduardo Marbán12957949586
Benoît Roux12049362215
Fereidoon Shahidi11995157796
Stephen Safe11678460588
Mark A. Tarnopolsky11564442501
Robert C. Haddon11257752712
Milton H. Saier11170754496
Hans J. Vogel111126062846
Paul D. N. Hebert11153766288
Peter T. Katzmarzyk11061856484
John Campbell107115056067
Linda F. Nazar10631852092
Network Information
Related Institutions (5)
University of California, Davis
180K papers, 8M citations

93% related

Michigan State University
137K papers, 5.6M citations

93% related

Texas A&M University
164.3K papers, 5.7M citations

92% related

University of British Columbia
209.6K papers, 9.2M citations

92% related

McGill University
162.5K papers, 6.9M citations

92% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202368
2022391
20212,574
20202,547
20192,264
20182,155