Institution
University of Guelph
Education•Guelph, Ontario, Canada•
About: University of Guelph is a education organization based out in Guelph, Ontario, Canada. It is known for research contribution in the topics: Population & Poison control. The organization has 26542 authors who have published 50553 publications receiving 1715255 citations. The organization is also known as: U of G & Guelph University.
Topics: Population, Poison control, DNA barcoding, Soil water, Skeletal muscle
Papers published on a yearly basis
Papers
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TL;DR: A detailed review of the debate surrounding the C‐value enigma, the various theories proposed to explain it, and the evidence in favour of a causal connection between DNA content and cell size is provided.
Abstract: Variation in DNA content has been largely ignored as a factor in evolution, particularly following the advent of sequence-based approaches to genomic analysis. The significant genome size diversity among organisms (more than 200 000-fold among eukaryotes) bears no relationship to organismal complexity and both the origins and reasons for the clearly non-random distribution of this variation remain unclear. Several theories have been proposed to explain this ‘C-value enigma’ (heretofore known as the ‘C-value paradox’), each of which can be described as either a ‘mutation pressure’ or ‘optimal DNA’ theory. Mutation pressure theories consider the large portion of non-coding DNA in eukaryotic genomes as either ‘junk’ or ‘selfish’ DNA and are important primarily in considerations of the origin of secondary DNA. Optimal DNA theories differ from mutation pressure theories by emphasizing the strong link between DNA content and cell and nuclear volumes. While mutation pressure theories generally explain this association with cell size as coincidental, the nucleoskeletal theory proposes a coevolutionary interaction between nuclear and cell volume, with DNA content adjusted adaptively following shifts in cell size. Each of these approaches to the C-value enigma is problematic for a variety of reasons and the preponderance of the available evidence instead favours the nucleotypic theory which postulates a causal link between bulk DNA amount and cell volume. Under this view, variation in DNA content is under direct selection via its impacts on cellular and organismal parameters. Until now, no satisfactory mechanism has been presented to explain this nucleotypic effect. However, recent advances in the study of cell cycle regulation suggest a possible ‘gene–nucleus interaction model’ which may account for it. The present article provides a detailed review of the debate surrounding the C-value enigma, the various theories proposed to explain it, and the evidence in favour of a causal connection between DNA content and cell size. In addition, a new model of nucleotypic influence is developed, along with suggestions for further empirical investigation. Finally, some evolutionary implications of genome size diversity are considered, and a broadening of the traditional ‘biological hierarchy’ is recommended.
640 citations
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01 Nov 1999TL;DR: A new language model for information retrieval is presented, which is based on a range of data smoothing techniques, including the Good-Turning estimate, curve-fitting functions, and model combinations, and can be easily extended to incorporate probabilities of phrases such as word pairs and word triples.
Abstract: Statistical language modeling has been successfully used for speech recognition, part-of-speech tagging, and syntactic parsing. Recently, it has also been applied to information retrieval. According to this new paradigm, each document is viewed as a language sample, and a query as a generation process. The retrieved documents are ranked based on the probabilities of producing a query from the corresponding language models of these documents. In this paper, we will present a new language model for information retrieval, which is based on a range of data smoothing techniques, including the Good-Turning estimate, curve-fitting functions, and model combinations. Our model is conceptually simple and intuitive, and can be easily extended to incorporate probabilities of phrases such as word pairs and word triples. The experiments with the Wall Street Journal and TREC4 data sets showed that the performance of our model is comparable to that of INQUERY and better than that of another language model for information retrieval. In particular, word pairs are shown to be useful in improving the retrieval performance.
640 citations
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University of Minnesota1, University of Maryland, College Park2, Iowa State University3, University of Oldenburg4, Utah State University5, Spanish National Research Council6, Wake Forest University7, University of Washington8, United States Department of Agriculture9, Colorado State University10, Michigan State University11, University of Queensland12, Trinity College, Dublin13, University of Toronto14, Lanzhou University15, University of California, San Diego16, Imperial College London17, University of Wisconsin-Madison18, University of Colorado Boulder19, United States Geological Survey20, Queensland University of Technology21, University of North Carolina at Chapel Hill22, University of Oxford23, University of Nebraska–Lincoln24, University of California, Berkeley25, University of Illinois at Urbana–Champaign26, University of Guelph27, University of Kentucky28, University of Melbourne29, Oregon State University30, Commonwealth Scientific and Industrial Research Organisation31, Swiss Federal Institute for Forest, Snow and Landscape Research32, Lancaster University33, Duke University34, University of California, Davis35
TL;DR: Testing the hypothesis that herbaceous plant species losses caused by eutrophication may be offset by increased light availability due to herbivory demonstrates that nutrients and herbivores can serve as counteracting forces to control local plant diversity through light limitation, independent of site productivity, soil nitrogen, herbivore type and climate.
Abstract: Human alterations to nutrient cycles and herbivore communities are affecting global biodiversity dramatically. Ecological theory predicts these changes should be strongly counteractive: nutrient addition drives plant species loss through intensified competition for light, whereas herbivores prevent competitive exclusion by increasing ground-level light, particularly in productive systems. Here we use experimental data spanning a globally relevant range of conditions to test the hypothesis that herbaceous plant species losses caused by eutrophication may be offset by increased light availability due to herbivory. This experiment, replicated in 40 grasslands on 6 continents, demonstrates that nutrients and herbivores can serve as counteracting forces to control local plant diversity through light limitation, independent of site productivity, soil nitrogen, herbivore type and climate. Nutrient addition consistently reduced local diversity through light limitation, and herbivory rescued diversity at sites where it alleviated light limitation. Thus, species loss from anthropogenic eutrophication can be ameliorated in grasslands where herbivory increases ground-level light.
639 citations
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TL;DR: If the modes of action of toxicants were better understood, we could more accurately predict their effects as pollutants; much knowledge already exists in medical sciences, and could be transferred Sublethal changes within fish have been demonstrated by many sensitive histopathological and biochemical techniques as mentioned in this paper.
638 citations
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TL;DR: Stability analyses were performed on a number of high-yielding maize hybrids, including three hybrids that have been involved in some of the highest maize yields recorded in producers’ fields, to examine the relationship between yield and yield stability.
631 citations
Authors
Showing all 26778 results
Name | H-index | Papers | Citations |
---|---|---|---|
Dirk Inzé | 149 | 647 | 74468 |
Norbert Perrimon | 138 | 610 | 73505 |
Bobby Samir Acharya | 133 | 1121 | 100545 |
Eduardo Marbán | 129 | 579 | 49586 |
Benoît Roux | 120 | 493 | 62215 |
Fereidoon Shahidi | 119 | 951 | 57796 |
Stephen Safe | 116 | 784 | 60588 |
Mark A. Tarnopolsky | 115 | 644 | 42501 |
Robert C. Haddon | 112 | 577 | 52712 |
Milton H. Saier | 111 | 707 | 54496 |
Hans J. Vogel | 111 | 1260 | 62846 |
Paul D. N. Hebert | 111 | 537 | 66288 |
Peter T. Katzmarzyk | 110 | 618 | 56484 |
John Campbell | 107 | 1150 | 56067 |
Linda F. Nazar | 106 | 318 | 52092 |