University of Hamburg

About: University of Hamburg is a education organization based out in Hamburg, Germany. It is known for research contribution in the topics: Population & Laser. The organization has 45564 authors who have published 89286 publications receiving 2850161 citations. The organization is also known as: Hamburg University.

Tumor metastasis: moving new biological insights into the clinic

Abstract: As the culprit behind most cancer-related deaths, metastasis is the ultimate challenge in our effort to fight cancer as a life-threatening disease. The explosive growth of metastasis research in the past decade has yielded an unprecedented wealth of information about the tumor-intrinsic and tumor-extrinsic mechanisms that dictate metastatic behaviors, the molecular and cellular basis underlying the distinct courses of metastatic progression in different cancers and what renders metastatic cancer refractory to available therapies. However, integration of such new knowledge into an improved, metastasis-oriented oncological drug development strategy is needed to thwart the development of metastatic disease at every stage of progression.

Berechnung der Seitenversetzung des totalreflektierten Strahles

Abstract: Zur Erklarung des Versuches von Goos und Hanchen werden die Beugungserscheinungen berechnet, die bei der Totalreflexion einer durch eine Blende begrenzten Lichtwelle am dunneren Medium eintreten. Bezeichnen λ1 die Wellenlange im dichteren Medium, ϑe den Einfallswinkel und φ = φ(ϑe) die bei der Totalreflexion auftretende Phasenverschiebung, so wird gezeigt, das der totalreflektierte Strahl eine Versetzung (GRAPHICS) senkrecht zur Strahlrichtung gegenuber einem Strahl erfahren mus, der statt dessen an einer Silberschicht reflektiert wird. Setzt man hierin fur dφ/dϑe die aus den Fresnelschen Formeln bekannten Werte ein, so ergibt sich fur die Strahlversetzung (GRAPHICS) Brechungsexponent des dichteren bzw. des dunneren Mediums, ϑg = Grenzwinkel der Totalreflexion), je nachdem der Vektor 𝔈 der elektrischen oder der magnetischen Feldstarke ℌ der einfallenden Lichtwelle in der ebenen Trennflache der beiden Medien liegt.

Employment and work-related issues in cancer survivors

Abstract: Purpose of this systematic literature review was to identify current knowledge about employment in cancer survivors. Sixty-four studies met inclusion criteria that were original papers published between 01/2000 and 11/2009. Overall, 63.5% of cancer survivors (range 24–94%) returned to work. The mean duration of absence from work was 151 days. Factors significantly associated with a greater likelihood of being employed or return to work were perceived employer accommodation, flexible working arrangements, counseling, training and rehabilitation services, younger age and cancer sites of younger individuals, higher levels of education, male gender, less physical symptoms, lower length of sick leave and continuity of care. Cancer survivors had a significantly increased risk for unemployment, early retirement and were less likely to be re-employed. Between 26% and 53% of cancer survivors lost their job or quit working over a 72-month period post diagnosis. Between 23% and 75% of patients who lost their job were re-employed. A high proportion of patients experienced at least temporary changes in work schedules, work hours, wages and a decline in work ability compared to non-cancer groups.

The COST 732 Best Practice Guideline for CFD simulation of flows in the urban environment: a summary

Abstract: This paper is a summary of the "Best Practice Guideline" (BPG) document (Franke et al., 2007) produced in the framework of the European COST Action 732 "Quality assurance and improvement of micro-scale meteorological models", available from the site given in the reference section. The full document provides guidelines for undertaking simulations that are used to evaluate micro-scale obstacle-accommodating meteorological models. This paper provides an overview of the topics covered in the full document without reproducing the specific recommendations.