Showing papers by "University of Hawaii at Manoa published in 2015"

Aquatic animal telemetry: A panoramic window into the underwater world

Abstract: BACKGROUND Global aquatic environments are changing profoundly as a result of human actions; consequently, so too are the ways in which organisms are distributing themselves through space and time. Our ability to predict organism and community responses to these alterations will be dependent on knowledge of animal movements, interactions, and how the physiological and environmental processes underlying them shape species distributions. These patterns and processes ultimately structure aquatic ecosystems and provide the wealth of ecosystem services upon which humans depend. Until recently, the vast size, opacity, and dynamic nature of the aquatic realm have impeded our efforts to understand these ecosystems. With rapid technological advancement over the past several decades, a suite of electronic tracking devices (e.g., acoustic and satellite transmitters) that can remotely monitor animals in these challenging environments are now available. Aquatic telemetry technology is rapidly accelerating our ability to observe animal behavior and distribution and, as a consequence, is fundamentally altering our understanding of the structure and function of global aquatic ecosystems. These advances provide the toolbox to define how future global aquatic management practices must evolve. ADVANCES Aquatic telemetry has emerged through technological advances in miniaturization, battery engineering, and software and hardware development, allowing the monitoring of organisms whose habitats range from the poles to the tropics and the photic zone to the abyssal depths. This is enabling the characterization of the horizontal and vertical movements of individuals, populations, and entire communities over scales of meters to tens of thousands of kilometers and over time frames of hours to years and even over the entire lifetimes of individuals. Electronic tags can now be equipped with sensors that measure ambient physical parameters (depth, temperature, conductivity, fluorescence), providing simultaneous monitoring of animals’ environments. By linking telemetry with biologgers (e.g., jaw-motion sensors), it is possible to monitor individual feeding events. In addition, other devices on instrumented animals can communicate with one another, providing insights into predator-prey interactions and social behavior. Coupling telemetry with minute nonlethal biopsy allows understanding of how trophic dynamics, population connectivity, and gene-level basis for organismal health and condition relate to movement. These advances are revolutionizing the scope and scales of questions that can be addressed on the causes and consequences of animal distribution and movement. OUTLOOK Aquatic animal telemetry has advanced rapidly, yet new challenges present themselves in coordination of monitoring across large-spatial scales (ocean basins), data sharing, and data assimilation. The continued advancement of aquatic telemetry lies in establishing and maintaining accessible and cost-effective infrastructure and in promoting multidisciplinary tagging approaches to maximize cost benefits. A united global network and centralized database will provide the mechanism for global telemetry data and will promote a transparent environment for data sharing that will, in turn, increase global communication, scope for collaboration, intellectual advancement, and funding opportunities. An overarching global network will realize the potential of telemetry, which is essential for advancing scientific knowledge and effectively managing globally shared aquatic resources and their ecosystems in the face of mounting human pressures and environmental change.

How to constrain your m dwarf: measuring effective temperature, bolometric luminosity, mass, and radius

Abstract: Precise and accurate parameters for late-type (late K and M) dwarf stars are important for characterization of any orbiting planets, but such determinations have been hampered by these stars' compl ...

A Three-dimensional Map of Milky Way Dust

Abstract: We present a three-dimensional map of interstellar dust reddening, covering three-quarters of the sky out to a distance of several kiloparsecs, based on Pan-STARRS 1 (PS1) and 2MASS photometry. The map reveals a wealth of detailed structure, from filaments to large cloud complexes. The map has a hybrid angular resolution, with most of the map at an angular resolution of 3.4¢ –13.7¢ , and a maximum distance resolution of ~25%. The three-dimensional distribution of dust is determined in a fully probabilistic framework, yielding the uncertainty in the reddening distribution along each line of sight, as well as stellar distances, reddenings, and classifications for 800 million stars detected by PS1. We demonstrate the consistency of our reddening estimates with those of two-dimensional emission-based maps of dust reddening. In particular, we find agreement with the Planck t353GHz -based reddening map to within 0.05 mag in E ( ) B V - to a depth of 0.5 mag, and explore systematics at reddenings less than E ( ) B V - » 0.08 mag. We validate our per-star reddening estimates by comparison with reddening estimates for stars with both Sloan Digital Sky Survey photometry and Sloan Extension for Galactic Understanding and Exploration spectral classifications, finding per-star agreement to within 0.1 mag out to a stellar E ( ) B V - of 1 mag. We compare our map to two existing three-dimensional dust maps, by Marshall et al. and Lallement et al., demonstrating our finer angular resolution, and better distance resolution compared to the former within ~3 kpc. The map can be queried or downloaded at http://argonaut.skymaps.info. We expect the three-dimensional reddening map presented here to find a wide range of uses, among them correcting for reddening and extinction for objects embedded in the plane of the Galaxy, studies of Galactic structure, calibration of future emission-based dust maps, and determining distances to objects of known reddening.

Motion artifacts in MRI: A complex problem with many partial solutions.

Abstract: Subject motion during magnetic resonance imaging (MRI) has been problematic since its introduction as a clinical imaging modality. While sensitivity to particle motion or blood flow can be used to provide useful image contrast, bulk motion presents a considerable problem in the majority of clinical applications. It is one of the most frequent sources of artifacts. Over 30 years of research have produced numerous methods to mitigate or correct for motion artifacts, but no single method can be applied in all imaging situations. Instead, a "toolbox" of methods exists, where each tool is suitable for some tasks, but not for others. This article reviews the origins of motion artifacts and presents current mitigation and correction methods. In some imaging situations, the currently available motion correction tools are highly effective; in other cases, appropriate tools still need to be developed. It seems likely that this multifaceted approach will be what eventually solves the motion sensitivity problem in MRI, rather than a single solution that is effective in all situations. This review places a strong emphasis on explaining the physics behind the occurrence of such artifacts, with the aim of aiding artifact detection and mitigation in particular clinical situations.

Genomics and the challenging translation into conservation practice

Abstract: The global loss of biodiversity continues at an alarming rate. Genomic approaches have been suggested as a promising tool for conservation practice as scaling up to genome-wide data can improve traditional conservation genetic inferences and provide qualitatively novel insights. However, the generation of genomic data and subsequent analyses and interpretations remain challenging and largely confined to academic research in ecology and evolution. This generates a gap between basic research and applicable solutions for conservation managers faced with multifaceted problems. Before the real-world conservation potential of genomic research can be realized, we suggest that current infrastructures need to be modified, methods must mature, analytical pipelines need to be developed, and successful case studies must be disseminated to practitioners.

Contribution of changes in atmospheric circulation patterns to extreme temperature trends

Abstract: This study identifies statistically significant trends in mid-atmospheric circulation patterns that partially explain observed changes in extreme temperature occurrence over Eurasia and North America; although the underlying cause of circulation pattern trends remains uncertain, most extreme temperature trends are shown to be consistent with thermodynamic warming. Changes in atmospheric circulation — the position of the jet stream or intertropical convergence zone for example — may be linked to changes in the occurrence of temperature extremes, but quantitative evidence is scarce. Daniel Horton and colleagues identify statistically significant trends in mid-atmospheric circulation patterns over Eurasia and North America, with the trends partially explaining observed changes in extreme temperature. At present, it is unclear whether these trends are related to greenhouse gas emissions or natural variability, and better-understood thermodynamic changes control more of the overall trends in extremes. But in some regions and for some types of extreme temperature events, shifts in atmospheric circulation are an important actor. Surface weather conditions are closely governed by the large-scale circulation of the Earth’s atmosphere. Recent increases in the occurrence of some extreme weather phenomena1,2 have led to multiple mechanistic hypotheses linking changes in atmospheric circulation to increasing probability of extreme events3,4,5. However, observed evidence of long-term change in atmospheric circulation remains inconclusive6,7,8. Here we identify statistically significant trends in the occurrence of atmospheric circulation patterns, which partially explain observed trends in surface temperature extremes over seven mid-latitude regions of the Northern Hemisphere. Using self-organizing map cluster analysis9,10,11,12, we detect robust circulation pattern trends in a subset of these regions during both the satellite observation era (1979–2013) and the recent period of rapid Arctic sea-ice decline (1990–2013). Particularly substantial influences include the contribution of increasing trends in anticyclonic circulations to summer and autumn hot extremes over portions of Eurasia and North America, and the contribution of increasing trends in northerly flow to winter cold extremes over central Asia. Our results indicate that although a substantial portion of the observed change in extreme temperature occurrence has resulted from regional- and global-scale thermodynamic changes, the risk of extreme temperatures over some regions has also been altered by recent changes in the frequency, persistence and maximum duration of regional circulation patterns.

Pacific western boundary currents and their roles in climate

Abstract: Pacific Ocean western boundary currents and the interlinked equatorial Pacific circulation system were among the first currents of these types to be explored by pioneering oceanographers. The widely accepted but poorly quantified importance of these currents-in processes such as the El Nino/Southern Oscillation, the Pacific Decadal Oscillation and the Indonesian Throughflow-has triggered renewed interest. Ongoing efforts are seeking to understand the heat and mass balances of the equatorial Pacific, and possible changes associated with greenhouse-gas-induced climate change. Only a concerted international effort will close the observational, theoretical and technical gaps currently limiting a robust answer to these elusive questions.

A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus

Abstract: Dengue is a rapidly emerging, mosquito-borne viral infection, with an estimated 400 million infections occurring annually. To gain insight into dengue immunity, we characterized 145 human monoclonal antibodies (mAbs) and identified a previously unknown epitope, the envelope dimer epitope (EDE), that bridges two envelope protein subunits that make up the 90 repeating dimers on the mature virion. The mAbs to EDE were broadly reactive across the dengue serocomplex and fully neutralized virus produced in either insect cells or primary human cells, with 50% neutralization in the low picomolar range. Our results provide a path to a subunit vaccine against dengue virus and have implications for the design and monitoring of future vaccine trials in which the induction of antibody to the EDE should be prioritized.

Ray Tracing for Radio Propagation Modeling: Principles and Applications

Abstract: This paper reviews the basic concepts of rays, ray tracing algorithms, and radio propagation modeling using ray tracing methods We focus on the fundamental concepts and the development of practical ray tracing algorithms The most recent progress and a future perspective of ray tracing are also discussed We envision propagation modeling in the near future as an intelligent, accurate, and real-time system in which ray tracing plays an important role This review is especially useful for experts who are developing new ray tracing algorithms to enhance modeling accuracy and improve computational speed

Multicenter Evaluation of the BioFire FilmArray Gastrointestinal Panel for Etiologic Diagnosis of Infectious Gastroenteritis

Abstract: The appropriate treatment and control of infectious gastroenteritis depend on the ability to rapidly detect the wide range of etiologic agents associated with the disease. Clinical laboratories currently utilize an array of different methodologies to test for bacterial, parasitic, and viral causes of gastroenteritis, a strategy that suffers from poor sensitivity, potentially long turnaround times, and complicated ordering practices and workflows. Additionally, there are limited or no testing methods routinely available for most diarrheagenic Escherichia coli strains, astroviruses, and sapoviruses. This study assessed the performance of the FilmArray Gastrointestinal (GI) Panel for the simultaneous detection of 22 different enteric pathogens directly from stool specimens: Campylobacter spp., Clostridium difficile (toxin A/B), Plesiomonas shigelloides, Salmonella spp., Vibrio spp., Vibrio cholerae, Yersinia enterocolitica, enteroaggregative E. coli, enteropathogenic E. coli, enterotoxigenic E. coli, Shiga-like toxin-producing E. coli (stx1 and stx2) (including specific detection of E. coli O157), Shigella spp./enteroinvasive E. coli, Cryptosporidium spp., Cyclospora cayetanensis, Entamoeba histolytica, Giardia lamblia, adenovirus F 40/41, astrovirus, norovirus GI/GII, rotavirus A, and sapovirus. Prospectively collected stool specimens (n = 1,556) were evaluated using the BioFire FilmArray GI Panel and tested with conventional stool culture and molecular methods for comparison. The FilmArray GI Panel sensitivity was 100% for 12/22 targets and ≥94.5% for an additional 7/22 targets. For the remaining three targets, sensitivity could not be calculated due to the low prevalences in this study. The FilmArray GI Panel specificity was ≥97.1% for all panel targets. The FilmArray GI Panel provides a comprehensive, rapid, and streamlined alternative to conventional methods for the etiologic diagnosis of infectious gastroenteritis in the laboratory setting. The potential advantages include improved performance parameters, a more extensive menu of pathogens, and a turnaround time of as short as 1 h.

Risk Factors for Exclusive E-Cigarette Use and Dual E-Cigarette Use and Tobacco Use in Adolescents

Abstract: OBJECTIVE:To describe electronic cigarette (e-cigarette) use and cigarette use among adolescents and determine whether established risk factors for smoking discriminate user categories. METHODS: School-based survey of 1941 high school students (mean age 14.6 years) in Hawaii; data collected in 2013. The survey assessed e-cigarette use and cigarette use, alcohol and marijuana use, and psychosocial risk and protective variables (eg, parental support, academic involvement, smoking expectancies, peer smoking, sensation seeking). Analysis of variance and multinomial regression examined variation in risk and protective variables across the following categories of ever-use: e-cigarette only, cigarette only, dual use (use of both products), and nonuser (never used either product). RESULTS: Prevalence for the categories was 17% (e-cigarettes only), 12% (dual use), 3% (cigarettes only), and 68% (nonusers). Dual users and cigarette-only users were highest on risk status (elevated on risk factors and lower on protective factors) compared with other groups. E-cigarette only users were higher on risk status than nonusers but lower than dual users. E-cigarette only users and dual users more often perceived e-cigarettes as healthier than cigarettes compared with nonusers. CONCLUSIONS: This study reports a US adolescent sample with one of the largest prevalence rates of e-cigarette only use in the existing literature. Dual use also had a substantial prevalence. The fact that e-cigarette only users were intermediate in risk status between nonusers and dual users raises the possibility that e-cigarettes are recruiting medium-risk adolescents, who otherwise would be less susceptible to tobacco product use.

Open science resources for the discovery and analysis of Tara Oceans data.

Abstract: The Tara Oceans expedition (2009–2013) sampled contrasting ecosystems of the world oceans, collecting environmental data and plankton, from viruses to metazoans, for later analysis using modern sequencing and state-of-the-art imaging technologies. It surveyed 210 ecosystems in 20 biogeographic provinces, collecting over 35,000 samples of seawater and plankton. The interpretation of such an extensive collection of samples in their ecological context requires means to explore, assess and access raw and validated data sets. To address this challenge, the Tara Oceans Consortium offers open science resources, including the use of open access archives for nucleotides (ENA) and for environmental, biogeochemical, taxonomic and morphological data (PANGAEA), and the development of on line discovery tools and collaborative annotation tools for sequences and images. Here, we present an overview of Tara Oceans Data, and we provide detailed registries (data sets) of all campaigns (from port-to-port), stations and sampling events.

Crucial Role of Lateral Size for Graphene Oxide in Activating Macrophages and Stimulating Pro-inflammatory Responses in Cells and Animals

Abstract: Graphene oxide (GO) is increasingly used in biomedical applications because it possesses not only the unique properties of graphene including large surface area and flexibility but also hydrophilicity and dispersibility in aqueous solutions. However, there are conflicting results on its biocompatibility and biosafety partially due to large variations in physicochemical properties of GO, and the role of these properties including lateral size in the biological or toxicological effects of GO is still unclear. In this study, we focused on the role of lateral size by preparing a panel of GO samples with differential lateral sizes using the same starting material. We found that, in comparison to its smaller counterpart, larger GO showed a stronger adsorption onto the plasma membrane with less phagocytosis, which elicited more robust interaction with toll-like receptors and more potent activation of NF-κB pathways. By contrast, smaller GO sheets were more likely taken up by cells. As a result, larger GO promoted greater M1 polarization, associated with enhanced production of inflammatory cytokines and recruitment of immune cells. The in vitro results correlated well with local and systemic inflammatory responses after GO administration into the abdominal cavity, lung, or bloodstream through the tail vein. Together, our study delineated the size-dependent M1 induction of macrophages and pro-inflammatory responses of GO in vitro and in vivo. Our data also unearthed the detailed mechanism underlying these effects: a size-dependent interaction between GO and the plasma membrane.

Optimal Ancient DNA Yields from the Inner Ear Part of the Human Petrous Bone.

Abstract: The invention and development of next or second generation sequencing methods has resulted in a dramatic transformation of ancient DNA research and allowed shotgun sequencing of entire genomes from fossil specimens. However, although there are exceptions, most fossil specimens contain only low (~ 1% or less) percentages of endogenous DNA. The only skeletal element for which a systematically higher endogenous DNA content compared to other skeletal elements has been shown is the petrous part of the temporal bone. In this study we investigate whether (a) different parts of the petrous bone of archaeological human specimens give different percentages of endogenous DNA yields, (b) there are significant differences in average DNA read lengths, damage patterns and total DNA concentration, and (c) it is possible to obtain endogenous ancient DNA from petrous bones from hot environments. We carried out intra-petrous comparisons for ten petrous bones from specimens from Holocene archaeological contexts across Eurasia dated between 10,000-1,800 calibrated years before present (cal. BP). We obtained shotgun DNA sequences from three distinct areas within the petrous: a spongy part of trabecular bone (part A), the dense part of cortical bone encircling the osseous inner ear, or otic capsule (part B), and the dense part within the otic capsule (part C). Our results confirm that dense bone parts of the petrous bone can provide high endogenous aDNA yields and indicate that endogenous DNA fractions for part C can exceed those obtained for part B by up to 65-fold and those from part A by up to 177-fold, while total endogenous DNA concentrations are up to 126-fold and 109-fold higher for these comparisons. Our results also show that while endogenous yields from part C were lower than 1% for samples from hot (both arid and humid) parts, the DNA damage patterns indicate that at least some of the reads originate from ancient DNA molecules, potentially enabling ancient DNA analyses of samples from hot regions that are otherwise not amenable to ancient DNA analyses.

A Three-Dimensional Map of Milky-Way Dust

Abstract: We present a three-dimensional map of interstellar dust reddening, covering three-quarters of the sky out to a distance of several kiloparsecs, based on Pan-STARRS 1 and 2MASS photometry. The map reveals a wealth of detailed structure, from filaments to large cloud complexes. The map has a hybrid angular resolution, with most of the map at an angular resolution of 3.4' to 13.7', and a maximum distance resolution of ~25%. The three-dimensional distribution of dust is determined in a fully probabilistic framework, yielding the uncertainty in the reddening distribution along each line of sight, as well as stellar distances, reddenings and classifications for 800 million stars detected by Pan-STARRS 1. We demonstrate the consistency of our reddening estimates with those of two-dimensional emission-based maps of dust reddening. In particular, we find agreement with the Planck 353 GHz optical depth-based reddening map to within 0.05 mag in E(B-V) to a depth of 0.5 mag, and explore systematics at reddenings less than E(B-V) ~ 0.08 mag. We validate our per-star reddening estimates by comparison with reddening estimates for stars with both SDSS photometry and SEGUE spectral classifications, finding per-star agreement to within 0.1 mag out to a stellar E(B-V) of 1 mag. We compare our map to two existing three-dimensional dust maps, by Marshall et al. (2006) and Lallement et al. (2013), demonstrating our finer angular resolution, and better distance resolution compared to the former within ~3 kpc. The map can be queried or downloaded at this http URL. We expect the three-dimensional reddening map presented here to find a wide range of uses, among them correcting for reddening and extinction for objects embedded in the plane of the Galaxy, studies of Galactic structure, calibration of future emission-based dust maps and determining distances to objects of known reddening.

Epoxy toughening with low graphene loading

Abstract: The toughening effects of graphene and graphene-derived materials on thermosetting epoxies are investigated. Graphene materials with various structures and surface functional groups are incorporated into an epoxy resin by in situ polymerization. Graphene oxide (GO) and GO modified with amine-terminated poly(butadiene-acrylonitrile) (ATBN) are chosen to improve the dispersion of graphene nanosheets in epoxy and increase their interfacial adhesion. An impressive toughening effect is observed with less than 0.1 wt% graphene. A maximum in toughness at loadings as small as 0.02 wt% or 0.04 wt% is observed for all four types of graphene studied. An epoxy nanocomposite with ATBN-modified GO shows a 1.5-fold improvement in fracture toughness and a corresponding 2.4-fold improvement in fracture energy at 0.04 wt% of graphene loading. At such low loadings, these graphene-type materials become economically feasible components of nanocomposites. A microcrack mechanism is proposed based on microscopy of the fracture surfaces. Due to the stress concentration by graphene nanosheets, microcracks may be formed to absorb the fracture energy. However, above a certain graphene concentration, the coalescence of microcracks appears to facilitate crack propagation, lowering the fracture toughness. Crack defl ection and pinning likely contribute to the slow increase in fracture toughness at higher loadings.

Spitzer Secondary Eclipses of the Dense, Modestly-irradiated, Giant Exoplanet HAT-P-20b Using Pixel-Level Decorrelation

Abstract: HAT-P-20b is a giant metal-rich exoplanet orbiting a metal-rich star. We analyze two secondary eclipses of the planet in each of the 3.6 and 4.5 μm bands of Warm Spitzer. We have developed a simple, powerful, and radically different method to correct the intra-pixel effect for Warm Spitzer data, which we call pixel-level decorrelation (PLD). PLD corrects the intra-pixel effect very effectively, but without explicitly using—or even measuring—the fluctuations in the apparent position of the stellar image. We illustrate and validate PLD using synthetic and real data and comparing the results to previous analyses. PLD can significantly reduce or eliminate red noise in Spitzer secondary eclipse photometry, even for eclipses that have proven to be intractable using other methods. Our successful PLD analysis of four HAT-P-20b eclipses shows a best-fit blackbody temperature of 1134 ± 29 K, indicating inefficient longitudinal transfer of heat, but lacking evidence for strong molecular absorption. We find sufficient evidence for variability in the 4.5 μm band that the eclipses should be monitored at that wavelength by Spitzer, and this planet should be a high priority for James Webb Space Telescope spectroscopy. All four eclipses occur about 35 minutes after orbital phase 0.5, indicating a slightly eccentric orbit. A joint fit of the eclipse and transit times with extant RV data yields e cos ω = 0.01352^(+0.00054)_(-0.00057) and establishes the small eccentricity of the orbit to high statistical confidence. HAT-P-20b is another excellent candidate for orbital evolution via Kozai migration or other three-body mechanisms.

Defining Successful Aging: A Tangible or Elusive Concept?

Abstract: Purpose of the Study: Everyone w ants to age successfully; however, the definition and criteria of successful aging remain vague for laypersons, researchers, and policymakers in spite of decades of research on the topic. This paper highlights work of scholars who made significant theoretical contributions to the topic. Design and Methods: A thorough review and evaluation of the literature on successful aging was undertaken. Results: Our review includes early gerontological definitions of successful aging and related concepts. Historical perspectives reach back to philosophical and religious texts, and more recent approaches have focused on both process- and outcomeoriented models of successful aging. We elaborate on Baltes and Baltes’ theory of selective optimization with compensation [Baltes, P. B., & Baltes, M. M. (1990a). Psychological perspectives on successful aging: The model of selective optimization with compensation. In P. B. Baltes & M. M. Baltes (Eds.), Successful aging: Perspectives from the behavioral sciences (pp. 1–34). United Kingdom: Cambridge University Press], Kahana and Kahana’s preventive and corrective proactivity model [Kahana, E., & Kahana, B. (1996). Conceptual and empirical advances in understanding aging well through proactive adaptation. In V. Bengtson (Ed.), Adulthood and aging: Research on continuities and discontinuities (pp. 18–40). New York: Springer], and Rowe and Kahn’s model of successful aging [Rowe, J. W., & Kahn, R. L. (1998). Successful aging. New York: Pantheon Books], outlining their commonalities and differences. Additional views on successful aging emphasize subjective versus objective perceptions of successful aging and relate successful aging to studies on healthy and exceptional longevity.

Towards predictive understanding of regional climate change

Abstract: This Review considers recent advances in our understanding of regional climate change, critically discusses outstanding issues, and recommends targets for future research. Regional information on climate change is urgently needed but often deemed unreliable. To achieve credible regional climate projections, it is essential to understand underlying physical processes, reduce model biases and evaluate their impact on projections, and adequately account for internal variability. In the tropics, where atmospheric internal variability is small compared with the forced change, advancing our understanding of the coupling between long-term changes in upper-ocean temperature and the atmospheric circulation will help most to narrow the uncertainty. In the extratropics, relatively large internal variability introduces substantial uncertainty, while exacerbating risks associated with extreme events. Large ensemble simulations are essential to estimate the probabilistic distribution of climate change on regional scales. Regional models inherit atmospheric circulation uncertainty from global models and do not automatically solve the problem of regional climate change. We conclude that the current priority is to understand and reduce uncertainties on scales greater than 100 km to aid assessments at finer scales.

How to Constrain Your M Dwarf: measuring effective temperature, bolometric luminosity, mass, and radius

Abstract: Precise and accurate parameters for late-type (late K and M) dwarf stars are important for characterization of any orbiting planets, but such determinations have been hampered by these stars' complex spectra and dissimilarity to the Sun. We exploit an empirically calibrated method to estimate spectroscopic effective temperature ($T_{\rm{eff}}$) and the Stefan-Boltzmann law to determine radii of 183 nearby K7-M7 single stars with a precision of 2-5%. Our improved stellar parameters enable us to develop model-independent relations between $T_{\rm{eff}}$ or absolute magnitude and radius, as well as between color and $T_{\rm{eff}}$. The derived $T_{\rm{eff}}$-radius relation depends strongly on [Fe/H], as predicted by theory. The relation between absolute $K_S$ magnitude and radius can predict radii accurate to $\simeq$3%. We derive bolometric corrections to the $VR_CI_CgrizJHK_S$ and Gaia passbands as a function of color, accurate to 1-3%. We confront the reliability of predictions from Dartmouth stellar evolution models using a Markov Chain Monte Carlo to find the values of unobservable model parameters (mass, age) that best reproduce the observed effective temperature and bolometric flux while satisfying constraints on distance and metallicity as Bayesian priors. With the inferred masses we derive a semi-empirical mass-absolute magnitude relation with a scatter of 2% in mass. The best-agreement models over-predict stellar $T_{\rm{eff}}$s by an average of 2.2% and under-predict stellar radii by 4.6%, similar to differences with values from low-mass eclipsing binaries. These differences are not correlated with metallicity, mass, or indicators of activity, suggesting issues with the underlying model assumptions e.g., opacities or convective mixing length.

A rocky planet transiting a nearby low-mass star

Abstract: M-dwarf stars--hydrogen-burning stars that are smaller than 60 per cent of the size of the Sun--are the most common class of star in our Galaxy and outnumber Sun-like stars by a ratio of 12:1. Recent results have shown that M dwarfs host Earth-sized planets in great numbers: the average number of M-dwarf planets that are between 0.5 to 1.5 times the size of Earth is at least 1.4 per star. The nearest such planets known to transit their star are 39 parsecs away, too distant for detailed follow-up observations to measure the planetary masses or to study their atmospheres. Here we report observations of GJ 1132b, a planet with a size of 1.2 Earth radii that is transiting a small star 12 parsecs away. Our Doppler mass measurement of GJ 1132b yields a density consistent with an Earth-like bulk composition, similar to the compositions of the six known exoplanets with masses less than six times that of the Earth and precisely measured densities. Receiving 19 times more stellar radiation than the Earth, the planet is too hot to be habitable but is cool enough to support a substantial atmosphere, one that has probably been considerably depleted of hydrogen. Because the host star is nearby and only 21 per cent the radius of the Sun, existing and upcoming telescopes will be able to observe the composition and dynamics of the planetary atmosphere.

Strong water isotopic anomalies in the martian atmosphere: probing current and ancient reservoirs.

Abstract: We measured maps of atmospheric water (H2O) and its deuterated form (HDO) across the martian globe, showing strong isotopic anomalies and a significant high deuterium/hydrogen (D/H) enrichment indicative of great water loss. The maps sample the evolution of sublimation from the north polar cap, revealing that the released water has a representative D/H value enriched by a factor of about 7 relative to Earth's ocean [Vienna standard mean ocean water (VSMOW)]. Certain basins and orographic depressions show even higher enrichment, whereas high-altitude regions show much lower values (1 to 3 VSMOW). Our atmospheric maps indicate that water ice in the polar reservoirs is enriched in deuterium to at least 8 VSMOW, which would mean that early Mars (4.5 billion years ago) had a global equivalent water layer at least 137 meters deep.

Seven-year efficacy and safety of treatment with tenofovir disoproxil fumarate for chronic hepatitis B virus infection.

Abstract: Background Long-term tenofovir disoproxil fumarate (TDF) treatment for chronic hepatitis B (CHB) is associated with sustained viral suppression and regression of fibrosis and cirrhosis at year 5 (240 weeks) and no TDF resistance through 6 years (288 weeks).

SAGITTARIUS II, DRACO II and LAEVENS 3: THREE NEW MILKY WAY SATELLITES DISCOVERED in the PAN-STARRS 1 3π SURVEY

Abstract: We present the discovery of three new Milky Way satellites from our search for compact stellar overdensities in the photometric catalog of the Panoramic Survey Telescope and Rapid Response System 1 (Pan-STARRS 1, or PS1) 3π survey. The first satellite, Laevens 3, is located at a heliocentric distance of d = 67 ± 3 kpc. With a total magnitude of MV = −4.4 ± 0.3 and a half-light radius of rh = 7 ± 2 pc, its properties resemble those of outer halo globular clusters. The second system, Draco II/Laevens 4, is a closer and fainter satellite (d ~ 20 kpc, MV = −2.9 ± 0.8), whose uncertain size (${r}_{h}={19}_{-6}^{+8}\;\mathrm{pc}$) renders its classification difficult without kinematic information; it could either be a faint and extended globular cluster or a faint and compact dwarf galaxy. The third satellite, Sagittarius II/Laevens 5 (Sgr II), has an ambiguous nature, as it is either the most compact dwarf galaxy or the most extended globular cluster in its luminosity range (${r}_{h}={37}_{-8}^{+9}\;\mathrm{pc}$ and MV = −5.2 ± 0.4). At a heliocentric distance of 67 ± 5 kpc, this satellite lies intriguingly close to the expected location of the trailing arm of the Sagittarius stellar stream behind the Sagittarius dwarf spheroidal galaxy (Sgr dSph). If confirmed through spectroscopic follow up, this connection would locate this part of the trailing arm of the Sagittarius stellar stream that has so far gone undetected. It would further suggest that Sgr II was brought into the Milky Way halo as a satellite of the Sgr dSph.

A multinational examination of weight bias: Predictors of anti-fat attitudes across four countries

Abstract: A multinational examination of weight bias: predictors of anti-fat attitudes across four countries

FOXO3: A Major Gene for Human Longevity--A Mini-Review.

Abstract: Background: The gene FOXO3 , encoding the transcription factor forkhead box O-3 (FoxO3), is one of only two for which genetic polymorphisms have

Extending the context of service: from encounters to ecosystems

Abstract: Purpose – The purpose of this paper is to extend conceptually the context of service beyond service encounters and servicescapes by applying a service-ecosystem approach to context and experiential view on value. Design/methodology/approach – We develop a conceptual framework of an extended service context that is based on an S-D logic, service-ecosystems view. Findings – The service ecosystem approach proposed here contributes to the advancement of “services” marketing research by extending the context of service in two ways: its emphasis on service as the basis of all exchange allows the consideration of all instances of value-in-use, in-context, to be considered as a service experience; its conceptualization of context broadens the time/place dimensions that conventionally restrain research in service encounters and servicescapes beyond physical, social, symbolic and relational dimensions to consider the multiplicity of institutions across a wider socio-historic space. Research limitations/implications...