University of Hawaii at Manoa

About: University of Hawaii at Manoa is a education organization based out in Honolulu, Hawaii, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 13693 authors who have published 25161 publications receiving 1023924 citations.

Interannual Variability of the Asian Summer Monsoon: Contrasts between the Indian and the Western North Pacific–East Asian Monsoons*

Abstract: Analyses of 50-yr NCEP-NCAR reanalysis data reveal remarkably different interannual variability between the Indian summer monsoon (ISM) and western North Pacific summer monsoon (WNPSM) in their temporal- spatial structures, relationships to El Nino, and teleconnections with midlatitude circulations. Thus, two circulation indices are necessary, which measure the variability of the ISM and WNPSM, respectively. A weak WNPSM features suppressed convection along 108-208N and enhanced rainfall along the mei-yu/baiu front. So the WNPSM index also provides a measure for the east Asian summer monsoon. An anomalous WNPSM exhibits a prominent meridional coupling among the Australian high, cross-equatorial flows, WNP monsoon trough, WNP subtropical high, east Asian subtropical front, and Okhotsk high. The WNP monsoon has leading spectral peaks at 50 and 16 months, whereas the Indian monsoon displays a primary peak around 30 months. The WNPSM is weak during the decay of an El Nino, whereas the ISM tends to abate when an El Nino develops. Since the late 1970s, the WNPSM has become more variable, but its relationship with El Nino remained steady; in contrast, the ISM has become less variable and its linkage with El Nino has dramatically declined. These contrasting features are in part attributed to the differing processes of monsoon-ocean interaction. Also found is a teleconnection between a suppressed WNPSM and deficient summer rainfall over the Great Plains of the United States. This boreal summer teleconnection is forced by the heat source fluctuation associated with the WNPSM and appears to be established through excitation of Rossby wave trains and perturbation of the jet stream that further excites downstream optimum unstable modes.

Maturational Constraints on Language Development

Abstract: This article reviews the second language research on age-related differences, as well as first language work needed to disambiguate some of the findings. Five conclusions are drawn, (a) Both the initial rate of acquisition and the ultimate level of attainment depend in part on the age at which learning begins. (b) There are sensitive periods governing language development, first or second, during which the acquisition of different linguistic abilities is successful and after which it is irregular and incomplete. (c) The age-related loss in ability is cumulative (not a catastrophic one-time event), affecting first one linguistic domain and then another, and is not limited to phonology, (d) The deterioration in some individuals begins as early as age 6—not at puberty as is often claimed. (e) Affective, input, and current cognitive explanations for the reduced ability are inadequate. The capacity for language development is maturationally constrained, and its decline probably reflects a progressive loss of neural plasticity, itself possibly associated with increasing myelination.

C-Reactive Protein, Fibrinogen, and Cardiovascular Disease Prediction

Abstract: Background There is debate about the value of assessing levels of C-reactive protein (CRP) and other biomarkers of inflammation for the prediction of first cardiovascular events. Methods We analyzed data from 52 prospective studies that included 246,669 participants without a history of cardiovascular disease to investigate the value of adding CRP or fibrinogen levels to conventional risk factors for the prediction of cardiovascular risk. We calculated measures of discrimination and reclassification during follow-up and modeled the clinical implications of initiation of statin therapy after the assessment of CRP or fibrinogen. Results The addition of information on high-density lipoprotein cholesterol to a prognostic model for cardiovascular disease that included age, sex, smoking status, blood pressure, history of diabetes, and total cholesterol level increased the C-index, a measure of risk discrimination, by 0.0050. The further addition to this model of information on CRP or fibrinogen increased the C-index by 0.0039 and 0.0027, respectively (P = 20%) (P = 20% and for those with certain other risk factors, such as diabetes, irrespective of their 10-year predicted risk), additional targeted assessment of CRP or fibrinogen levels in the 13,199 remaining participants at intermediate risk could help prevent approximately 30 additional cardiovascular events over the course of 10 years. Conclusions In a study of people without known cardiovascular disease, we estimated that under current treatment guidelines, assessment of the CRP or fibrinogen level in people at intermediate risk for a cardiovascular event could help prevent one additional event over a period of 10 years for every 400 to 500 people screened. (Funded by the British Heart Foundation and others.)

Group Work, Interlanguage Talk,and Second Language Acquisition.

Abstract: The use of group work in classroom second language learning has long been supported by sound pedagogical arguments. Recently, however, a psycholinguistic rationale for group work has emerged from second language acquisition research on conversation between non-native speakers, or interlanguage talk. Provided careful attention is paid to the structure of tasks students work on together, the negotiation work possible in group activity makes it an attractive alternative to the teacher-led, “lockstep” mode and a viable classroom substitute for individual conversations with native speakers.