University of Houston

About: University of Houston is a education organization based out in Houston, Texas, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 23074 authors who have published 53903 publications receiving 1641968 citations.

Economic Conditions and the Presidential Vote

Abstract: This analysis demonstrates that the relative growth of per capita income change is an important determinant of post-World War II presidential election outcomes. Per capita income change is even a better predictor of presidential election outcomes than the electorate's relative attraction to the Democratic and Republican candidates as calibrated in National Election Study surveys. The significance of this finding is discussed.

Strangeness in nuclear physics

Abstract: Extensions of nuclear physics to the strange sector are reviewed, covering data and models of Λ and other hypernuclei, multistrange matter, and antikaon bound states and condensation. Past achievements are highlighted, present unresolved problems are discussed, and future directions are outlined.

Solvation and hydration of proteins and nucleic acids: a theoretical view of simulation and experiment.

Abstract: Many theoretical, computational, and experimental techniques recently have been successfully used for description of the solvent distribution around macromolecules. In this Account, we consider recent developments in the areas of protein and nucleic acid solvation and hydration as seen by experiment, theory, and simulations. We find that in most cases not only the general phenomena of solvation but even local hydration patterns are more accurately discussed in the context of water distributions rather than individual molecules of water. While a few localized or highresidency waters are often associated with macromolecules in solution (or crystals from aqueous liquors), these are readily and accurately included in this more general description. The goal of this Account is to review the theoretical models used for the description of the interfacial solvent structure on the border near DNA and protein molecules. In particular, we hope to highlight the progress in this field over the past five years with a focus on comparison of simulation and experimental results.

Rodent model of nicotine abstinence syndrome.

Abstract: Few animals models are currently in use for the recognized clinical problem of nicotine dependence and abstinence. This study introduces a rapid and convenient model using the rat. Sixteen male rats were rendered nicotine dependent by 7 days of continuous subcutaneous infusion of either 3 mg/kg/day (n = 8) or 9 mg/kg/day (n = 8) nicotine tartrate salt; 8 control rats were infused with saline alone. Rats were observed for 15 min before, during, and after the drug infusion period using a tally sheet modified from a standard checklist of opiate abstinence signs. There were few signs observed in any group at baseline and at the end of the infusion period. However, nicotine-infused rats showed a significant, dose-related increase over the control group at 16 h after the end of infusion, largely subsiding by 40 h. The most frequently observed signs during withdrawals included: teeth-chattering/chews, writhes/gasps, ptosis, tremors/shakes, and yawns. A significant drop in locomotor activity and increase in weight gain following termination of nicotine infusion provided additional evidence of an abstinence syndrome. This syndrome was alleviated by SC administration of 0.4 mg/kg nicotine tartrate.