Institution
University of Houston
Education•Houston, Texas, United States•
About: University of Houston is a education organization based out in Houston, Texas, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 23074 authors who have published 53903 publications receiving 1641968 citations.
Topics: Population, Poison control, Anxiety, Context (language use), Catalysis
Papers published on a yearly basis
Papers
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TL;DR: These five groups of subjects demonstrated no differences on demographic characteristics but significantly differed on Alcohol Use Inventory subscales, a temptation to drink and abstinence self-efficacy measure as well as several outcome variables.
683 citations
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TL;DR: The increasing incidence of ciprofloxacin resistance among gram-negative bacilli that has occurred coincident with increased use of fluoroquinolones will be necessary to limit this downward trend.
Abstract: ContextPrevious surveillance studies have documented increasing rates of antimicrobial
resistance in US intensive care units (ICUs) in the early 1990s.ObjectivesTo assess national rates of antimicrobial resistance among gram-negative
aerobic isolates recovered from ICU patients and to compare these rates to
antimicrobial use.Design and SettingParticipating institutions, representing a total of 43 US states plus
the District of Columbia, provided antibiotic susceptibility results for 35 790
nonduplicate gram-negative aerobic isolates recovered from ICU patients between
1994 and 2000.Main Outcome MeasuresEach institution tested approximately 100 consecutive gram-negative
aerobic isolates recovered from ICU patients. Organisms were identified to
the species level. Susceptibility tests were performed, and national fluoroquinolone
consumption data were obtained.ResultsThe activity of most antimicrobial agents against gram-negative aerobic
isolates showed an absolute decrease of 6% or less over the study period.
The overall susceptibility to ciprofloxacin decreased steadily from 86% in
1994 to 76% in 2000 and was significantly associated with increased national
use of fluoroquinolones.ConclusionsThis study documents the increasing incidence of ciprofloxacin resistance
among gram-negative bacilli that has occurred coincident with increased use
of fluoroquinolones. More judicious use of fluoroquinolones will be necessary
to limit this downward trend.
679 citations
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Joint Genome Institute1, University of California, Berkeley2, National Institute for Medical Research3, Genetic Information Research Institute4, National Institutes of Health5, Rice University6, University of California, Irvine7, University of Manchester8, Los Alamos National Laboratory9, United States Department of Health and Human Services10, Washington University in St. Louis11, Okinawa Institute of Science and Technology12, St. Jude Children's Research Hospital13, Nara Institute of Science and Technology14, University of Maryland, Baltimore15, University of Évry Val d'Essonne16, University of Rochester Medical Center17, University of Houston18, University of Calgary19, Cincinnati Children's Hospital Medical Center20, Yale University21
TL;DR: The western clawed frog Xenopus tropicalis is an important model for vertebrate development that combines experimental advantages of the African clawed frogs Xenopus laevis with more tractable genetics.
Abstract: The western clawed frog Xenopus tropicalis is an important model for vertebrate development that combines experimental advantages of the African clawed frog Xenopus laevis with more tractable genetics. Here we present a draft genome sequence assembly of X. tropicalis. This genome encodes more than 20,000 protein-coding genes, including orthologs of at least 1700 human disease genes. Over 1 million expressed sequence tags validated the annotation. More than one-third of the genome consists of transposable elements, with unusually prevalent DNA transposons. Like that of other tetrapods, the genome of X. tropicalis contains gene deserts enriched for conserved noncoding elements. The genome exhibits substantial shared synteny with human and chicken over major parts of large chromosomes, broken by lineage-specific chromosome fusions and fissions, mainly in the mammalian lineage.
679 citations
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TL;DR: In this article, a model of cross-functional project groups was developed and hypotheses were tested in a study of 93 research and new product development groups from four companies, and the results showed that functio...
Abstract: A model of cross-functional project groups was developed and hypotheses were tested in a study of 93 research and new product development groups from four companies. The results showed that functio...
676 citations
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TL;DR: This review is a discussion of the relevance of cerebral oxidative stress to impairment of emotional and mental well-being in neuropsychiatric disorders, including anxiety disorders and depression.
Abstract: Biochemical integrity of the brain is vital for normal functioning of the central nervous system (CNS). One of the factors contributing to cerebral biochemical impairment is a chemical process called oxidative stress. Oxidative stress occurs upon excessive free radical production resulting from an insufficiency of the counteracting antioxidant response system. The brain, with its high oxygen consumption and lipid-rich content, is highly susceptible to oxidative stress. Therefore, oxidative stress–induced damage to the brain has a strong potential to negatively impact normal CNS functions. Although oxidative stress has historically been considered to be involved mainly in neurodegenerative disorders such as Alzheimer disease, Huntington disease, and Parkinson disease, its involvement in neuropsychiatric disorders, including anxiety disorders and depression, is beginning to be recognized. This review is a discussion of the relevance of cerebral oxidative stress to impairment of emotional and mental well-being.
674 citations
Authors
Showing all 23345 results
Name | H-index | Papers | Citations |
---|---|---|---|
Matthew Meyerson | 194 | 553 | 243726 |
Gad Getz | 189 | 520 | 247560 |
Eric Boerwinkle | 183 | 1321 | 170971 |
Pulickel M. Ajayan | 176 | 1223 | 136241 |
Zhenan Bao | 169 | 865 | 106571 |
Marc Weber | 167 | 2716 | 153502 |
Steven N. Blair | 165 | 879 | 132929 |
Martin Karplus | 163 | 831 | 138492 |
Dongyuan Zhao | 160 | 872 | 106451 |
Xiang Zhang | 154 | 1733 | 117576 |
Jan-Åke Gustafsson | 147 | 1058 | 98804 |
James M. Tour | 143 | 859 | 91364 |
Guanrong Chen | 141 | 1652 | 92218 |
Naomi J. Halas | 140 | 435 | 82040 |
Antonios G. Mikos | 138 | 694 | 70204 |