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Institution

University of Iceland

EducationReykjavik, Suðurnes, Iceland
About: University of Iceland is a education organization based out in Reykjavik, Suðurnes, Iceland. It is known for research contribution in the topics: Population & Genome-wide association study. The organization has 5423 authors who have published 16199 publications receiving 694762 citations. The organization is also known as: Háskóli Íslands.


Papers
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Journal ArticleDOI
TL;DR: The hypothesis that autoimmune mechanisms may contribute to the pathogenesis of IgAD is supported, after a genome-wide association study in 430 affected individuals from Sweden and Iceland and 1,090 ethnically matched controls.
Abstract: Lennart Hammarstrom, Tim Behrens and colleagues report the results of a genome wide association study of selective immunoglobulin A deficiency, the most common form of primary immunodeficiency in humans. They validated previously known HLA haplotype associations and identified a new risk variant in IFIH1.

145 citations

Journal ArticleDOI
TL;DR: This work describes a community-driven effort, in which more than 20 experts in S. Typhimurium biology and systems biology collaborated to reconcile and expand the S.Typhonium BiGG knowledge-base, and uses the consensus MR to identify potential multi-target drug therapy approaches.
Abstract: Background: Metabolic reconstructions (MRs) are common denominators in systems biology and represent biochemical, genetic, and genomic (BiGG) knowledge-bases for target organisms by capturing currently available information in a consistent, structured manner. Salmonella enterica subspecies I serovar Typhimurium is a human pathogen, causes various diseases and its increasing antibiotic resistance poses a public health problem. Results: Here, we describe a community-driven effort, in which more than 20 experts in S. Typhimurium biology and systems biology collaborated to reconcile and expand the S. Typhimurium BiGG knowledge-base. The consensus MR was obtained starting from two independently developed MRs for S. Typhimurium. Key results of this reconstruction jamboree include i) development and implementation of a community-based workflow for MR annotation and reconciliation; ii) incorporation of thermodynamic information; and iii) use of the consensus MR to identify potential multi-target drug therapy approaches. Conclusion: Taken together, with the growing number of parallel MRs a structured, community-driven approach will be necessary to maximize quality while increasing adoption of MRs in experimental design and interpretation.

145 citations

Journal ArticleDOI
TL;DR: In this paper, the authors analyse the structuring of time among academic employees in Iceland, how they organize and reconcile their work and family life and whether gender is a defining factor in this context.
Abstract: In the article we analyse the structuring of time among academic employees in Iceland, how they organize and reconcile their work and family life and whether gender is a defining factor in this context. Our analysis shows clear gender differences in time use. Although flexible working hours help academic parents to organize their working day and fulfil the ever-changing needs of family members, the women, rather than men interviewed, seem to be stuck with the responsibility of domestic and caring issues because of this very same flexibility. It seems to remove, for more women than for men, the possibility of going home early or not being on call. The flexibility and the gendered time use seem thus to reproduce traditional power relations between women and men and the gender segregated division in the homes.

145 citations

Journal ArticleDOI
TL;DR: Growth results were improved under the less expensive light of 660 nm LEDs, and illumination was augmented by optimization at systematic level, providing for a biomass productivity of up to 2.11 gDCW/L/day, the best results ever reported.

144 citations

Journal ArticleDOI
TL;DR: The ITEX control data were used to test the phenological responses to background temperature variation across sites spanning latitudinal and moisture gradients and showed mixed responses, pointing to a complex suite of changes in plant communities and ecosystem function in high latitudes and elevations as the climate warms.
Abstract: The rapidly warming temperatures in high-latitude and alpine regions have the potential to alter the phenology of Arctic and alpine plants, affecting processes ranging from food webs to ecosystem trace gas fluxes The International Tundra Experiment (ITEX) was initiated in 1990 to evaluate the effects of expected rapid changes in temperature on tundra plant phenology, growth and community changes using experimental warming Here, we used the ITEX control data to test the phenological responses to background temperature variation across sites spanning latitudinal and moisture gradients The dataset overall did not show an advance in phenology; instead, temperature variability during the years sampled and an absence of warming at some sites resulted in mixed responses Phenological transitions of high Arctic plants clearly occurred at lower heat sum thresholds than those of low Arctic and alpine plants However, sensitivity to temperature change was similar among plants from the different climate zones Plants of different communities and growth forms differed for some phenological responses Heat sums associated with flowering and greening appear to have increased over time These results point to a complex suite of changes in plant communities and ecosystem function in high latitudes and elevations as the climate warms

144 citations


Authors

Showing all 5561 results

NameH-indexPapersCitations
Albert Hofman2672530321405
Kari Stefansson206794174819
Ronald Klein1941305149140
Eric Boerwinkle1831321170971
Unnur Thorsteinsdottir167444121009
Vilmundur Gudnason159837123802
Hakon Hakonarson152968101604
Bernhard O. Palsson14783185051
Andrew T. Hattersley146768106949
Fernando Rivadeneira14662886582
Rattan Lal140138387691
Jonathan G. Seidman13756389782
Christine E. Seidman13451967895
Augustine Kong13423789818
Timothy M. Frayling133500100344
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202377
2022209
20211,222
20201,118
20191,140
20181,070