Institution
University of Iceland
Education•Reykjavik, Suðurnes, Iceland•
About: University of Iceland is a education organization based out in Reykjavik, Suðurnes, Iceland. It is known for research contribution in the topics: Population & Genome-wide association study. The organization has 5423 authors who have published 16199 publications receiving 694762 citations. The organization is also known as: Háskóli Íslands.
Papers published on a yearly basis
Papers
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TL;DR: The hypothesis that autoimmune mechanisms may contribute to the pathogenesis of IgAD is supported, after a genome-wide association study in 430 affected individuals from Sweden and Iceland and 1,090 ethnically matched controls.
Abstract: Lennart Hammarstrom, Tim Behrens and colleagues report the results of a genome wide association study of selective immunoglobulin A deficiency, the most common form of primary immunodeficiency in humans. They validated previously known HLA haplotype associations and identified a new risk variant in IFIH1.
145 citations
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University of Iceland1, University of California, San Diego2, University of Basel3, Donald Danforth Plant Science Center4, Braunschweig University of Technology5, National Health Research Institutes6, Katholieke Universiteit Leuven7, École Polytechnique Fédérale de Lausanne8, Icahn School of Medicine at Mount Sinai9, University of Wisconsin-Madison10, Technical University of Dortmund11, University of Manchester12, Pacific Northwest National Laboratory13
TL;DR: This work describes a community-driven effort, in which more than 20 experts in S. Typhimurium biology and systems biology collaborated to reconcile and expand the S.Typhonium BiGG knowledge-base, and uses the consensus MR to identify potential multi-target drug therapy approaches.
Abstract: Background: Metabolic reconstructions (MRs) are common denominators in systems biology and represent biochemical, genetic, and genomic (BiGG) knowledge-bases for target organisms by capturing currently available information in a consistent, structured manner. Salmonella enterica subspecies I serovar Typhimurium is a human pathogen, causes various diseases and its increasing antibiotic resistance poses a public health problem. Results: Here, we describe a community-driven effort, in which more than 20 experts in S. Typhimurium biology and systems biology collaborated to reconcile and expand the S. Typhimurium BiGG knowledge-base. The consensus MR was obtained starting from two independently developed MRs for S. Typhimurium. Key results of this reconstruction jamboree include i) development and implementation of a community-based workflow for MR annotation and reconciliation; ii) incorporation of thermodynamic information; and iii) use of the consensus MR to identify potential multi-target drug therapy approaches. Conclusion: Taken together, with the growing number of parallel MRs a structured, community-driven approach will be necessary to maximize quality while increasing adoption of MRs in experimental design and interpretation.
145 citations
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TL;DR: In this paper, the authors analyse the structuring of time among academic employees in Iceland, how they organize and reconcile their work and family life and whether gender is a defining factor in this context.
Abstract: In the article we analyse the structuring of time among academic employees in Iceland, how they organize and reconcile their work and family life and whether gender is a defining factor in this context. Our analysis shows clear gender differences in time use. Although flexible working hours help academic parents to organize their working day and fulfil the ever-changing needs of family members, the women, rather than men interviewed, seem to be stuck with the responsibility of domestic and caring issues because of this very same flexibility. It seems to remove, for more women than for men, the possibility of going home early or not being on call. The flexibility and the gendered time use seem thus to reproduce traditional power relations between women and men and the gender segregated division in the homes.
145 citations
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TL;DR: Growth results were improved under the less expensive light of 660 nm LEDs, and illumination was augmented by optimization at systematic level, providing for a biomass productivity of up to 2.11 gDCW/L/day, the best results ever reported.
144 citations
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Florida International University1, National Ecological Observatory Network2, Grand Valley State University3, University of Notre Dame4, University of Alaska Fairbanks5, American Museum of Natural History6, University of British Columbia7, Aarhus University8, University of Melbourne9, University Centre in Svalbard10, University of Iceland11, Norwegian University of Life Sciences12, Colorado State University13, University of Gothenburg14, Marine Biological Laboratory15, La Trobe University16, University of Alaska Anchorage17
TL;DR: The ITEX control data were used to test the phenological responses to background temperature variation across sites spanning latitudinal and moisture gradients and showed mixed responses, pointing to a complex suite of changes in plant communities and ecosystem function in high latitudes and elevations as the climate warms.
Abstract: The rapidly warming temperatures in high-latitude and alpine regions have the potential to alter the phenology of Arctic and alpine plants, affecting processes ranging from food webs to ecosystem trace gas fluxes The International Tundra Experiment (ITEX) was initiated in 1990 to evaluate the effects of expected rapid changes in temperature on tundra plant phenology, growth and community changes using experimental warming Here, we used the ITEX control data to test the phenological responses to background temperature variation across sites spanning latitudinal and moisture gradients The dataset overall did not show an advance in phenology; instead, temperature variability during the years sampled and an absence of warming at some sites resulted in mixed responses Phenological transitions of high Arctic plants clearly occurred at lower heat sum thresholds than those of low Arctic and alpine plants However, sensitivity to temperature change was similar among plants from the different climate zones Plants of different communities and growth forms differed for some phenological responses Heat sums associated with flowering and greening appear to have increased over time These results point to a complex suite of changes in plant communities and ecosystem function in high latitudes and elevations as the climate warms
144 citations
Authors
Showing all 5561 results
Name | H-index | Papers | Citations |
---|---|---|---|
Albert Hofman | 267 | 2530 | 321405 |
Kari Stefansson | 206 | 794 | 174819 |
Ronald Klein | 194 | 1305 | 149140 |
Eric Boerwinkle | 183 | 1321 | 170971 |
Unnur Thorsteinsdottir | 167 | 444 | 121009 |
Vilmundur Gudnason | 159 | 837 | 123802 |
Hakon Hakonarson | 152 | 968 | 101604 |
Bernhard O. Palsson | 147 | 831 | 85051 |
Andrew T. Hattersley | 146 | 768 | 106949 |
Fernando Rivadeneira | 146 | 628 | 86582 |
Rattan Lal | 140 | 1383 | 87691 |
Jonathan G. Seidman | 137 | 563 | 89782 |
Christine E. Seidman | 134 | 519 | 67895 |
Augustine Kong | 134 | 237 | 89818 |
Timothy M. Frayling | 133 | 500 | 100344 |