Institution
University of Ioannina
Education•Ioannina, Greece•
About: University of Ioannina is a education organization based out in Ioannina, Greece. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 7654 authors who have published 20594 publications receiving 671560 citations. The organization is also known as: Panepistimio Ioanninon.
Papers published on a yearly basis
Papers
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TL;DR: This work suggests that network meta-regression is employed to account for small-study effects in a set of related meta-analyses and describes the methods by re-analysing two published networks.
Abstract: Suggested methods for exploring the presence of small-study effects in a meta-analysis and the possibility of publication bias are associated with important limitations. When a meta-analysis comprises only a few studies, funnel plots are difficult to interpret, and regression-based approaches to test and account for small-study effects have low power. Assuming that the cause of funnel plot asymmetry is likely to affect an entire research field rather than only a particular comparison of interventions, we suggest that network meta-regression is employed to account for small-study effects in a set of related meta-analyses. We present several possible models for the direction and distribution of small-study effects and we describe the methods by re-analysing two published networks. Copyright © 2012 John Wiley & Sons, Ltd.
312 citations
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TL;DR: It is demonstrated that the method detects both fades and abrupt cuts with high accuracy and it is shown that it captures satisfactorily the visual content of the shot.
Abstract: New methods for detecting shot boundaries in video sequences and for extracting key frames using metrics based on information theory are proposed. The method for shot boundary detection relies on the mutual information (MI) and the joint entropy (JE) between the frames. It can detect cuts, fade-ins and fade-outs. The detection technique was tested on the TRECVID2003 video test set having different types of shots and containing significant object and camera motion inside the shots. It is demonstrated that the method detects both fades and abrupt cuts with high accuracy. The information theory measure provides us with better results because it exploits the inter-frame information in a more compact way than frame subtraction. It was also successfully compared to other methods published in literature. The method for key frame extraction uses MI as well. We show that it captures satisfactorily the visual content of the shot.
311 citations
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TL;DR: ESR1 is a susceptibility gene for fractures, and XbaI determines fracture risk by mechanisms independent of BMD, which demonstrates the value of adequately powered studies with standardized genotyping and clinical outcomes in defining effects of common genetic variants on complex diseases.
Abstract: 2orless.Conversely,wefoundsignificantreductions in fracture risk. In women homozygous for the absence of an XbaI recognition site, the adjusted odds of all fractures were reduced by 19% (odds ratio, 0.81 [95% CI, 0.710.93]; P=.002) and vertebral fractures by 35% (odds ratio, 0.65 [95% CI, 0.49-0.87]; P=.003). Effects on fractures were independent of BMD and unaltered in adjusted analyses. No significant effects on fracture risk were seen for PvuII and TA repeats. Conclusions ESR1 is a susceptibility gene for fractures, and XbaI determines fracture risk by mechanisms independent of BMD. Our study demonstrates the value of adequately powered studies with standardized genotyping and clinical outcomes in defining effects of common genetic variants on complex diseases.
311 citations
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TL;DR: The EuroCTO Club’s aim is to provide a platform for the development of a new generation of interpreters and interpreters for the 21st Century.
Abstract: Georgios Sianos1*, MD, PhD, FESC; Gerald S. Werner2, MD, PhD, FESC, FACC, FSCI; Alfredo R. Galassi3, MD, FESC, FACC, FSCAI; Michail I. Papafaklis4, MD, PhD; Javier Escaned5, MD, PhD, FESC; David Hildick-Smith6, MD, FESC; Evald Hoj Christiansen7, MD, PhD; Anthony Gershlick8, MD, FRCP, FESC; Mauro Carlino9, MD, FESC; Angelos Karlas1, MD; Nikolaos V. Konstantinidis1, MD; Salvatore D. Tomasello3, MD; Carlo Di Mario10, MD, PhD, FRCP, FESC; Nicolaus Reifart11, MD, PhD, FESC for the EuroCTO Club
310 citations
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TL;DR: In many countries, a low proportion of patients with RA exercise is reported, which may alert rheumatologists to motivate their patients to increasePhysical inactivity is associated with decreased morbidity and mortality.
Abstract: Objective
Regular physical activity is associated with decreased morbidity and mortality. Traditionally, patients with rheumatoid arthritis (RA) have been advised to limit physical exercise. We studied the prevalence of physical activity and associations with demographic and disease-related variables in patients with RA from 21 countries.
Methods
The Questionnaires in Standard Monitoring of Patients with Rheumatoid Arthritis (QUEST-RA) is a cross-sectional study that includes a self-report questionnaire and clinical assessment of nonselected consecutive outpatients with RA who are receiving usual clinical care. Frequency of physical exercise (≥30 minutes with at least some shortness of breath, sweating) is queried with 4 response options: ≥3 times weekly, 1–2 times weekly, 1–2 times monthly, and no exercise.
Results
Between January 2005 and April 2007, a total of 5,235 patients from 58 sites in 21 countries were enrolled in QUEST-RA: 79% were women, >90% were white, mean age was 57 years, and mean disease duration was 11.6 years. Only 13.8% of all patients reported physical exercise ≥3 times weekly. The majority of the patients were physically inactive with no regular weekly exercise: >80% in 7 countries, 60–80% in 12 countries, and 45% and 29% in 2 countries, respectively. Physical inactivity was associated with female sex, older age, lower education, obesity, comorbidity, low functional capacity, and higher levels of disease activity, pain, and fatigue.
Conclusion
In many countries, a low proportion of patients with RA exercise. These data may alert rheumatologists to motivate their patients to increase physical activity levels.
310 citations
Authors
Showing all 7724 results
Name | H-index | Papers | Citations |
---|---|---|---|
John P. A. Ioannidis | 185 | 1311 | 193612 |
Kay-Tee Khaw | 174 | 1389 | 138782 |
Elio Riboli | 158 | 1136 | 110499 |
Mercouri G. Kanatzidis | 152 | 1854 | 113022 |
Dimitrios Trichopoulos | 135 | 818 | 84992 |
Gyorgy Vesztergombi | 133 | 1444 | 94821 |
Niki Saoulidou | 132 | 1065 | 81154 |
Apostolos Panagiotou | 132 | 1370 | 88647 |
Ioannis Evangelou | 131 | 1225 | 82178 |
Ioannis Papadopoulos | 129 | 1201 | 85576 |
Nikolaos Manthos | 129 | 1256 | 81865 |
Panagiotis Kokkas | 128 | 1234 | 81051 |
Costas Foudas | 128 | 1112 | 83048 |
Zoltan Szillasi | 128 | 1214 | 84392 |
Matthias Schröder | 126 | 1421 | 82990 |