Showing papers by "University of Iowa published in 1975"
01 Oct 1975
TL;DR: Graph Theory and Its Applications to Problems of Society and its Applications to Algorithms and Computer Science.
Abstract: Introductory Graph Theory with ApplicationsGraph Theory with ApplicationsResearch Topics in Graph Theory and Its ApplicationsChemical Graph TheoryMathematical Foundations and Applications of Graph EntropyGraph Theory with Applications to Engineering and Computer ScienceGraphs Theory and ApplicationsQuantitative Graph TheoryApplied Graph TheoryChemical Graph TheoryA First Course in Graph TheoryGraph TheoryGraph Theory with ApplicationsGraph Theory with ApplicationsSpectra of GraphsFuzzy Graph Theory with Applications to Human TraffickingApplications of Graph TheoryChemical Applications of Graph TheoryRecent Advancements in Graph TheoryA Textbook of Graph TheoryGraph Theory and Its Engineering ApplicationsGraph Theory, Combinatorics, and ApplicationsAdvanced Graph Theory and CombinatoricsTopics in Intersection Graph TheoryGraph Theory with Applications to Engineering and Computer ScienceGraph Theory and Its Applications, Second EditionHandbook of Research on Advanced Applications of Graph Theory in Modern SocietyGraph Theory with Applications to Algorithms and Computer ScienceGraph TheoryGraph Theory with Algorithms and its ApplicationsGraph TheoryGraph Theory with ApplicationsGraph Theory ApplicationsHandbook of Graph TheoryGraph Theory and Its Applications to Problems of SocietyBasic Graph Theory with ApplicationsTen
809 citations
667 citations
TL;DR: The results indicate that the integrity of the olivo-cerebellar system is necessary for the acquisition and retention of this form of motor learning, but that the cerebellum itself is not the seat of such learning.
Abstract: Specific chemical lesion of the rat inferior olive by intraperitoneal administration of 3-acetylpyridine prevents recuperation from motor abnormalities generated by unilateral labyrinthine lesion. Moreover, in animals that have recuperated from the balyrinthine lesion, 3-acetylpyridine produces a reversal of the symptoms within 2 hours of administration. These results indicate that the integrity of the olivo-cerebellar system is necessary for the acquisition and retention of this form of motor learning, but that the cerebellum itself is not the seat of such learning.
396 citations
TL;DR: Six hundred patients underwent diagnostic flexible fiberoptic bronchoscopy (FFB) and the two diseases most frequently encountered were bronchogenic carcinoma and bacterial infection, with an overall 69 percent diagnostic success.
386 citations
TL;DR: A rapid procedure for resolving phosphohistone from ATP and its metabolites based on the specific absorption of phosphorylated histone onto phosphocellulose paper is devised.
350 citations
TL;DR: The administration of single oral doses of delta‐9‐tetrahydrocannabinol (THC) to patients with cancer pain demonstrated a mild analgesic effect, however, THC induced side effects that would prohibit its therapeutic use including somnolence, dizziness, ataxia, and blurred vision at a dose of 20 mg.
Abstract: The administration of single oral doses of delta-9-tetrahydrocannabinol (THC) to patients with cancer pain demonstrated a mild analgesic effect. At a dose of 20 mg, however, THC induced side effects that would prohibit its therapeutic use including somnolence, dizziness, ataxia, and blurred vision. Alarming adverse reactions were also observed at this dose. THC, 10 mg, was well tolerated and, despite its sedative effect, may analgesic potential.
348 citations
TL;DR: A new neck suction device which may have significant advantages over earlier models is developed which is simple and inexpensive to construct, one model fits most adults in relative comfort, and the design of the chamber permits rapid initiation ofneck suction to preselected levels leading to stimulus-related cardiac slowing and arterial hypotension.
293 citations
TL;DR: Both diazepam and scopolamine impaired memory functions although the action of the latter drug was more pronounced and prolonged and the deficit appeared to be in the storage process leaving retrieval processes unaffected.
Abstract: The effects of intramuscular injections of diazepam (0.3 mg/kg) and scopolamine (8 Μg/kg) on memory processes and subjective moods were studied in 36 volunteers. Subjects (Ss) were tested in groups of four in a double blind procedure with treatments distributed according to a Latin square design. Lists of words were presented to Ss who were then tested with an immediate free recall test prior to drug administration. Following injection delayed free recall and recognition tests were given. Subsequently two sets of lists were presented separately and tested in the same fashion. Two of the lists in the last set were composed of words falling into distinct categories. Memory was additionally analyzed by testing immediate recall of digit sequences and employing a visual recognition test. Subjective moods were evaluated with a rating questionnaire. Both diazepam and scopolamine impaired memory functions although the action of the latter drug was more pronounced and prolonged. The deficit appeared to be in the storage process leaving retrieval processes unaffected. Scopolamine in addition interfered with organizational processes. Subjectively, scopolamine also produced a larger sedative effect than diazepam.
261 citations
TL;DR: In this article, a weak nonthermal continuum, radiated by the earth from energetic electrons in the outer radiation zone, is studied and it is shown that the frequency spectrum of the continuum radiation consists of two components, a trapped component, which is permanently trapped within the magnetosphere at frequencies below the solar wind plasma frequency, and an escaping component which propagates freely away from the earth at frequencies above the plasma frequency.
Abstract: A weak nonthermal continuum, radiated by the earth from energetic electrons in the outer radiation zone, is studied. It is shown that the frequency spectrum of the continuum radiation consists of two components, a trapped component, which is permanently trapped within the magnetosphere at frequencies below the solar wind plasma frequency, and an escaping component which propagates freely away from the earth at frequencies above the solar wind plasma frequency. Direction finding measurements and measurements of the spatial distribution of intensity for both components indicated that the continuum radiation is generated (1) in a broad region which extends through the morning and early afternoon immediately beyond the plasmapause boundary, and (2) over a broad range of latitudes, including the magnetic equator. Possible mechanisms by which this radiation is generated, including gyro-synchrotron radiation from energetic electrons in the outer radiation zone, are discussed.
255 citations
246 citations
TL;DR: A preliminary trial of oral delta-9-tetrahydrocannabinol (THC) demonstrated an analgesic effect of the drug in patients experiencing cancer pain, and pain relief significantly superior to placebo was demonstrated at high dose levels.
Abstract: A preliminary trial of oral delta-9-tetrahydrocannabinol (THC) demonstrated an analgesic effect of the drug in patients experiencing cancer pain. Placebo and 5, 10, 15, and 20 mg THC were administered double blind to ten patients. Pain relief significantly superior to placebo was demonstrated at high dose levels (15 and 20 mg). At these levels, substantial sedation and mental clouding were reported.
TL;DR: Changes in myocardial perfusion and motion may be due to transient undetected ischemia in the segments struck by the ultrasound beam, or to passive alteration of the motion of the normally perfused areas by the severe dyskinesis of the adjacent ischemic myocardium.
Abstract: In order to evaluate the relationship between regional myocardial perfusion and segmental dyskinesis, 22 open chest dogs were studied using ultrasound to register cardiac wall motion and radioactive labeled microspheres to determine myocardial perfusion. In six dogs, motion and perfusion were correlated at two levels of partial circumflex coronary artery occlusion followed by complete occlusion. A good correlation between declining myocardial perfusion of all the ischemic segments and development of aneurysmal bulging (during isometric contraction) was seen: r = minus 0.80. A similar correlation between myocardial perfusion and endocardial wall velocity (during systolic ejection) was observed: r = 0.92. In nine dogs, the effect of 45 minutes of complete coronary occlusion followed by 30 minutes of reperfusion was evaluated with respect to perfusion and motion. After coronary reperfusion myocardial perfusion of the ischemic area returned to control levels (from 32.6 +/- 3.5 to 130.3 +/- 13.3 ml/100 g/min), but aneurysmal bulging during isometric contraction persisted. Endocardial wall velocity during systolic ejection showed a variable response to reperfusion, achieving values ranging from 32% to 162% of the preocclusion levels. In seven dogs the ultrasound beam was reflected off nonischemic myocardium adjacent to areas of ischemia resulting from coronary occlusion. Despite preservation of normal myocardial perfusion in these nonischemic areas wall motion abnormalities were evident: endocardial wall velocity declined from 25.8 +/- 5.8 to 14.0 +/- 4.9 mm/sec (P less than 0.01), and aneurysmal bulging in three animals. These changes may be due to transient undetected ischemia in the segments struck by the ultrasound beam, or to passive alteration of the motion of the normally perfused areas by the severe dyskinesis of the adjacent ischemic myocardium.
TL;DR: The hypothesis of a periventricular receptor site for angiotensin is supported and it is suggested that systemically generated ang Elliotensin and angiotENSin endogenous to the brain may use the ventricular route as a means of access to the sensitive perivocentular site.
TL;DR: It is pleased to see colleagues in industry and academia adopt the M4- approach to solve difficult pharmacological and toxicological problems, and in large measure, this has been the greatest reward for efforts initially presented before the membership of the American Society of Pharmacognosy in 1973.
TL;DR: The data provide a basis for speculation on the possible difference in allocation of calories to growth and non‐growth in the two groups of normal infants.
Abstract: Fomon, S. J., Filer, L. J., Jr, Thomas, L. N., Anderson, T. A. and Nelson, S. E. (Department of Pediatrics, University Hospital, University of Iowa, Iowa City, USA). Influence of formula concentration on caloric intake and growth of normal infants. Acta Paediatr Stand, 64:172, 1975.–Fifteen fullterm female infants were enrolled in each of two feeding groups and all but one completed the proposed period of observation to age 112 days. Formulas prepared from the same ingredients (fat-free milk solids, a mixture of corn and coconut oils, lactose, vitamins and minerals) were fed ad libitum to both groups. Formula concentration was 54 kcal/100 ml for one group and 100 kcal/100 ml for the other. A limited selection of commercially prepared strained foods was permitted after 28 days of age. Weighed intakes of food were recorded for each day of study. During the interval 8 through 41 days of age, the infants fed the 54 kcal/100 ml formula consumed a considerably greater quantity of food but fewer calories than did those fed the 100 kcal/100 ml formula. Those fed the 54 kcal/100 ml formula also gained less weight. These differences between feeding groups were statistically significant. After 41 days of age, mean caloric intakes (kcal/kg/day) and rates of gain in weight were similar for the two feeding groups. The data provide a basis for speculation on the possible difference in allocation of calories to growth and non-growth in the two groups.
TL;DR: For the pioneering studies in the area of gastric emptying and motility, thanks are given to Beaumont, Marbiax, the Sala manacas (father and son), Carlson, Carlson, Al varez, Thomas, Ivy and their co-workers, and more recently Code and Daniel and their groups.
TL;DR: The use of the monkey as a model for the study of methanol poisoning is presented, and the possible use of 4-methylpyrazole in the treatment of metanol poisoning is implicit.
TL;DR: In this article, the Hawkeye-1 and IMP-8 satellites were used to locate the source region of auroral kilometric radiation, which exhibits peak intensities between about 100 kHz and 300 kHz and emits intense sporadic bursts lasting for between one half hour to several hours.
Abstract: Direction finding measurements with plasma wave experiments onboard the Hawkeye-1 and IMP-8 satellites were used to locate the source region of auroral kilometric radiation. The radiation exhibits peak intensities between about 100 kHz and 300 kHz, and emits intense sporadic bursts lasting for between one half hour to several hours. The total power emitted in this frequency range exceeds 10 to the 9th power watts at peak intensity. The occurrence of the radiation is known to be closely associated with bright auroral arcs which occur in the local evening auroral regions.
TL;DR: In various species of Ips a connection has been convincingly demonstrated between the production of these pheromones in the hindgut and either ingestion of phloem or exposure of the beetles to host plant oleoresin.
Abstract: THE aggregation pheromones of the bark beetle, Ips paraconfusus Lanier1 are expelled in the faecal pellets of male beetles feeding on the phloem of Pinus ponderosa2,3. These substances, cis-verbenol, ipsenol, and ipsdienol4, seem to originate in the hindgut5 but the precise site of their biosynthesis has not been determined. In various species of Ips a connection has been convincingly demonstrated between the production of these pheromones in the hindgut and either ingestion of phloem or exposure of the beetles to host plant oleoresin6. More specifically, exposure of individuals of certain species of Ips to myrcene can result in an increased production of ipsenol and ipsdienol7 and exposure of certain species of Dendroctonus to α–pinene results in an increased production of cis- and trans-verbenol8–10 in the hindgut. It seems therefore that a precursor–product relationship exists between certain host plant substances such as α-pinene and myrcene and the three aggregation pheromones mentioned above.
Journal Article•
TL;DR: This article reviewed consumer behavior and found that attitude change, information seeking, and brand loyalty are correlated with the concept of cognitive dissonance in consumer behavior, and they also found that consumer behavior can be categorized into three types of behaviors: positive, negative, and negative.
Abstract: Researchers in consumer behavior have attempted to relate attitude change, information seeking, and brand loyalty to the concept of cognitive dissonance. The writers review the consumer behavior li...
TL;DR: In this paper, simultaneous measurements of the electric and magnetic field spectral densities in the earth's bow shock were made by a plasma wave experiment on the Imp 6 spacecraft. The frequency range of the plasma wave detector was 20 Hz to 200 kHz.
Abstract: Simultaneous measurements were made of the electric and magnetic field spectral densities in the earth's bow shock by a plasma wave experiment on the Imp 6 spacecraft. The frequency range of the plasma wave detector was 20 Hz to 200 kHz. Electric fields were measured with high-sensitivity 100-m long dipole antennas and magnetic fields were measured with single-turn loop antennas. Two components are distinguished in the electric field spectrum in the bow shock: one component has a broad peak centered in the region 200-800 Hz, while the other component increases monotonically with decreasing frequency. The magnetic field spectrum has only one component that increases monotonically with decreasing frequency and has an upper cutoff frequency near the local electron gyrofrequency. This magnetic field turbulence is judged to be caused by whistler mode waves. The monotonic component of the electric field spectrum is thought to be the electric field spectrum of these whistler mode waves.
TL;DR: Results indicate that the covalent bond between thrombin and the inhibitor is a carboxylic ester, which supports an earlier proposal that formation of the complex includes the formation of a covalend bond.
TL;DR: In this paper, two studies were conducted to assess whether distraction has drivelike effects on task performance, and the results indicate that distraction (e.g., when momentarily suspended, performance on simple tasks was facilitated in both studies, whereas performance on the complex task used in Study 2 was still impaired.
Abstract: Two studies were conducted to assess whether distraction has drivelike effects on task performance. In both, the effects of distraction over all trials interacted significantly with the nature of the task; jlistraction tended to facilitate the performances of simple tasks and signirkantiy~impaired performance on complex tasks. Moreover, analyses focusing upon drive carryover effects generally replicated these effects; when distraction was momentarily suspended, performance on simple tasks was facilitated in both studies (compared to nondistraction controls, joint p<.OS), whereas performance on the complex task used in Study 2 was still impaired. Results of Study 2 indicate that lack of impairment on the complex task in Study 1 on such trials was due to practice effects of repeated testing. These results indicate that distraction (a) has drivelike properties and (b) does not invariably impair performance. These results are discussed in terms of recent research and theorizing in the area of social facilitation.
TL;DR: Results of the study suggest that the percentage distribution of the total force produced by the finger flexors to each individual finger bear a constant relationship regardless of wrist position.
TL;DR: Perception of direction was significantly more accurate on the left hand than on the righthanded subjects, underscoring the importance of familial background as a determinant of performances reflecting asymmetry in hemispheric function.
TL;DR: A sensitive and specific assay for formic acid in body fluids has been developed based on the reaction of formate with bacterial formate dehydrogenase coupled to a diaphorase-catalyzed reduction of the nonfluorescent dye resazurin to the fluorescent substance resorufin.