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Showing papers by "University of Jena published in 1976"


Journal ArticleDOI
01 Dec 1976-Drugs
TL;DR: It is recommended that bleeding disturbances under hormonal steroid contraception in a previously regular cycle be regarded as loss of reliability; they should be remedied and taken as a sign to search for uncontrolled drug taking.
Abstract: On the basis of well documented biochemical and pharmacological data about the influence of drug mediated enzyme induction on the biotransformation of natural and synthetic sex steroids, practical consequences for hormonal steroid contraception are described and discussed. Clinical reports dealing with this problem are still sparse.

40 citations


Journal ArticleDOI
TL;DR: In this article, the Poynting vector of a plane electromagnetic wave diffracted by the gravitational field of a large spherical body (large compared to its Schwarzschild radius) is given.
Abstract: This paper gives the Poynting vector of a plane electromagnetic wave diffracted by the gravitational field of a large spherical body (large compared to its Schwarzschild radius) and shows in detail how this body works as a gravitational lens. The most interesting results are (1) an extreme amplification of intensity near to the axis of symmetry in the far field behind the body, with a factor of 10 times the Schwarzschild radius divided by the wavelength of the light, and (2) the appearance of double images, differing in shape and position from the predictions of geometrical optics.

32 citations



Journal ArticleDOI
J. Härtwig1
TL;DR: In this paper, the authors examined the X-ray diffraction phenomena for an extremely asymmetric Laue case with two reciprocal lattice points on the Ewald sphere and a little angle between the crystal surface and the diffracted beam exactly fulfilling the Bragg condition.
Abstract: X-ray diffraction phenomena are examined for an extremely asymmetric Laue case with two reciprocal lattice points on the Ewald sphere and a little angle between the crystal surface and the diffracted beam exactly fulfilling the Bragg condition. The results received by means of a modified theory are compared with the conventional theory. Contradictions in the papers published up to now are discussed. Es werden Interferenzphanomene von Rontgenstrahlen fur einen stark asymmetrischen Lauefall mit zwei reziproken Gitterpunkten auf der Ausbreitungskugel und einem kleinen Winkel zwischen Kristalloberflache und den abgebeugten, streng die Braggbedingung erfullenden Strahl untersucht. Die nach einer modifizierten Theorie gewonnenen Ergebnisse werden mit den nach der konventionellen Theorie gewonnenen verglichen. Widerspruche in bisher erschienenen Arbeiten werden diskutiert.

24 citations


Journal ArticleDOI
TL;DR: In this paper, an electron-microscopic study of 9 nasopharyngeal angiofibromas was performed in order to elucidate the ultrastructural characteristics.
Abstract: An electron-microscopic study of 9 nasopharyngeal angiofibromas was performed in order to elucidate the ultrastructural characteristics. Stromal fibroblasts and proliferating cells of the microvasculature were found. The stromal fibroblasts were subdivided into 3 different groups: (1) “classical” fibroblasts, (2) fibroblasts with histiocytelike features, and (3) fibroblasts with myoid features. By proliferation the cells of the capillary vessels change into stromal cells. A particular pattern of nuclei and dense intranuclear granules is only found in stromal fibroblasts. Consequently fibroblasts as well as cells of the microvasculature contribute to the pool of tumor cells.

23 citations


Journal ArticleDOI
M. Adam1, R. Vitášek1, Z. Deyl1, G. Felsch1, J. Musilová1, Z. Olšovská1 
TL;DR: It has been proved that collagen from rheumatoid patients contains a distinctly higher proportion of insoluble fraction resistant to heat solubilization, and the finding that r heumatoid skin and nodules contain a higherportion of collagen type III is found.

20 citations


Journal ArticleDOI
TL;DR: Investigations in regenerating tendon tissue of rats and guinea pigs showed proof of the great plasticity of fibroblasts which function as stem cells in connective tissue regeneration, and led to the conclusion, that a part of fibrablasts in the proliferating connectives during tendon repair may derive from pericytes.

16 citations


Journal ArticleDOI
D. Linke1, I. Böckel1
TL;DR: In this article, the formation and properties of the glasses in the system Ge-Sb-S are described, and the limits of the glass-forming region correspond approximately to the lines joining GeS, GeS3 and Sb2S3 in the composition diagram.
Abstract: Die Glasbildung im System Ge–Sb–S und die Eigenschaften der Glaser werden beschrieben. Der Glasbildungsbereich wird im Konzentrationsdreieck etwa durch die Geraden GeS–Sb2S3 und GeS3–Sb2S3 begrenzt; bei hoheren Schwefel- bzw. Antimongehalten werden ausgedehnte Gebiete mit Mikro- und Makrophasentrennung beobachtet. Die Dichten der Glaser steigen proportional zur mittleren Molmasse der Formeleinheit. Die Transformationstemperaturen liegen bei 200 bis 350°C, die Mikroharten zwischen 150 und 300 kp/mm2. Beide Grosen lassen sich mit den naherungsweise errechneten Atomisierungsenthalpien der Glaser korrelieren. Correlations between Properties of Chalcogenide Glasses. I. The System Germanium—Antimony—Sulphur Glass formation and properties of the glasses in the system Ge–Sb–S are described. The limits of the glass-forming region correspond approximately to the lines joining GeS, GeS3 and Sb2S3 in the composition diagram. The results indicate two regions of liquid immiscibility, both at high sulphur and high antimony contents. The densities increase linearly with the average molecular weights per formula-unit of the glasses. Glass transition temperatures are in the range from 200 to 350°C, and values of Vickers hardness between 150 and 300 kp/mm2 have been measured. Both properties are in a linear relationship with the approximate values for the atomization energies of the glasses.

15 citations


Journal ArticleDOI
TL;DR: In this article, the retention indices of bicyclo[n.m.0]alkanes with 6−13 carbon atoms have been determined by gas-solid chromatography (GSC) on a column packed with graphitized thermal carbon black (GTR) and by gas liquid chromatography on glass capillaries coated with squalane (S), and Ucon 50 HB 280X polar, respectively.

15 citations


Journal ArticleDOI
I. Wenz1, Wolfgang Loesche1, U. Till1, Henning Petermann1, Anton Horn1 
TL;DR: The anion-exchange chromatography of commercial NADH using a potassium bicarbonate solution as eluent yields highly pure NADH with good stability and 12 compounds are also separated which act as dehydrogenase inhibitors.

14 citations


Journal ArticleDOI
TL;DR: In this article, the processes which influence the decomposition of 4MgCO 3 ·-Mg(OH) 2 · 4H 2 O, could be determined by systematical variation of the analytical parameters.

Journal ArticleDOI
N. Höser1, R. Dargel1
TL;DR: Evidence is provided for respiration-dependent stimulation by inorganic phosphate of Mg2’ release from rat liver mitochondria and the results suggest this effect might be due to a concerted action of in organic phosphate and endogenous Ca” on the mitochondrial structure.

Book ChapterDOI
01 Jan 1976
TL;DR: In this article, calculations of the Ca-oxalate activity product, TT, are reported together with experimental results, and the system under regard and computed results are described in Fig. 1.
Abstract: Calculations of complex-chemical equilibria from total component concentrations, pH and equilibrium constants have proved to be very usefull to determine activity products of the ionized components of stone-forming salts (1–4). In the present paper, calculations of the Ca-oxalate activity product, TT, are reported together with experimental results. Perrins algorithm for chemical equilibrium calculations (5) has been included into a program which allows for the dependence of the activity coefficients an ionic strength according to the Davies-equation (4). The system under regard and computed results are described in Fig. 1. (A more detailed description will be given in a forthcoming paper (6)).

Book ChapterDOI
01 Jan 1976
TL;DR: In the GDR, X-ray diffraction has been developed as a standardized method for semi-quantitative stone analysis and this is performed in special district-controlled laboratories.
Abstract: The analysis of stones is essential in the study of the genesis and treatment of urolithiasis. However, qualitative chemical analysis of the stone components is not sufficient for this purpose. In the GDR, X-ray diffraction has been developed as a standardized method for semi-quantitative stone analysis. This is performed in special district-controlled laboratories. Each stone is analysed in its entirety or more thoroughly in terms of its nucleus and shells.

Journal ArticleDOI
TL;DR: In this article, the critical temperature Tc is determined as a function of the film thickness and the dependence of the critical magnetic field Hc∥ and Hc⟂ on the reduced temperature is measured.
Abstract: Studies on superconducting thin films of vanadium for determining the influence of production parameters are performed. The critical temperature Tc is determined as a function of the film thickness and the dependence of the critical magnetic field Hc∥ and Hc⟂ on the reduced temperature is measured. Moreover the dependence of the critical magnetic field and the critical current density on the angle are measured and the film constants λ, ξ, and x are determined. The experimental values are compared with values, which are calculated from the Ginsburg-Landau theory.

Journal ArticleDOI
TL;DR: In this article, the synthesis of [5-tyrosine, 6-glycine]-, [8-tyr, 6Gly], [5.8-di-tric, 6gly]-bradykinin, and the C-terminal partial sequences are described.
Abstract: Es wird die Synthese von [5-Tyr, 6-Gly]-, [8-Tyr, 6-Gly]-, [5.8-Di-Tyr, 6-Gly]-Bradykinin und der C-terminalen Partialsequenzen beschrieben. Die Bradykininanaloga werden mit dem Dansylrest und einem Iminoxylradikal-Spinmarker substituiert. Peptides. XXV. Synthesis of Bradykinin Analogues and Partial Sequences with Tyrosine for Electron Spin Resonance and Fluorescence Studies The syntheses of [5-tyrosine, 6-glycine]-, [8-tyrosine, 6-glycine]-, [5,8-Di-tyrosine, 6-glycine]-bradykinin, and the C-terminal partial sequences are described. The analogues have been labelled with the dansyl group or an aminoxyl radical, respectively.


Book ChapterDOI
01 Jan 1976
TL;DR: By statistical evaluation of 17, 000 urolith analyses, 63% were found to consist essentially of calcium oxalate as discussed by the authors, and 74% of these correspond to the monohydrate and only 26 % to the thermo-dynamically unstable dihydrate.
Abstract: By statistical evaluation of 17 000 urolith analyses 63% were shown to consist essentially of calcium oxalate. 74 % of these correspond to the monohydrate and only 26 % to the thermo-dynamically unstable dihydrate. On the other hand, according to previous studies it is to be expected that weddellite represents the primary phase in the formation of oxalate stones. This corresponds to the observation that in the concretions of oxalate stone patients nearly exclusively crystals of weddellite are detected.

Journal ArticleDOI
TL;DR: In this article, Messungen der longitudinalen 13 C-Relaxationszeiten protonierter Kohlenstoffatome in monosubstituierten Diphenylen beschrieben.

Journal ArticleDOI
TL;DR: The gold-labeled Anti-A Hel could be used succesfully for labeling of A antigen sites of human A 1 B erythrocytes as demonstrated in thin sections and immuno freeze-etching.

Journal ArticleDOI
TL;DR: In this paper, the highest radioactivity of the isolated macrolid antibiotic was found in isobutyric acid which is esterified with mycarose, a precursor of isovaleric acid.


Journal ArticleDOI
TL;DR: A two-step affinity technique is described for light microscopic demonstration of the Concanavalin A, Agaricus bisporus lectin and Ricinus communis lectin binding sites by means of various FITC-labeled human and rabbit serum protein fractions basing on their carbohydrate content.
Abstract: A two-step affinity technique is described for light microscopic demonstration of the Concanavalin A, Agaricus bisporus lectin and Ricinus communis lectin binding sites by means of various FITC-labeled human and rabbit serum protein fractions. Experiments for the visualization of the Lens culinaris lectin and the Pisum sativum lectin binding sites gaves negative results. The technique consist of two reaction steps which involve the incubation of tissue sections in the lectins followed by the visualization of receptor-bound lectins with FITC-labeled serum protein fractions basing on their carbohydrate content. The specificity of the technique could be demonstrated by the addition of the hapten or by incubation in the FITC-labeled serum protein fractions only. In contrast to the direct or indirect staining methods only very small amounts of purified lectins are necessary.

Journal ArticleDOI
TL;DR: In this paper, a radikalischen Losungspolymerisation of the system p-Vinylbenzolboronsaure-bis(trimethylsilyl)-ester (1b) (M1)/Styrol wurden with Hilfe von Boranalysen ermittelt.
Abstract: Die Copolymerisationsparameter der radikalischen Losungspolymerisation der Systeme p-Vinylbenzolboronsaure (1a) (M1)/Styrol bzw. p-Vinylbenzolboronsaure-bis(trimethylsilyl)-ester (1b) (M1)/Styrol wurden mit Hilfe von Boranalysen ermittelt: 1a: r1=0,28±0,06 und r2=0,83±0,04 1b: r1=0,28±0,10 und r2=0,87±0,08 Durch Abspaltung der Trimethylsilyl-Gruppen lassen sich die 1b/Styrol-Copolymere leicht in 1a/Styrol-Copolymere uberfuhren. Von einigen Copolymeren wurden Lithium-, Natrium- und Kaliumsalze hergestellt. Die Losungsviskositaten der polymeren Boronsauren in Benzol/Methanol-Gemischen und in Dimethylsulfoxid (DMSO) hangen deutlich vom Boronsauregehalt ab. In Benzol/Methanol-Gemischen kann die Vorzugssolvatation der Boronsauregruppen durch Methanol nachgewiesen werden. Die Einfuhrung von Boronsauregruppen in Polystyrol ist mit einem Anstieg der Glasubergangstemperatur verbunden. Torsionsschwingungsmessungen zeigen, das sich beim Schmelzpressen der Polymeren Vernetzungen ausbilden, bei denen es sich um Boronsaureanhydridstrukturen handelt. Diese Vernetzungen konnen durch protische Losungsmittel gespalten werden. The reactivity ratios of the radical solution copolymerization for the systems p-vinylbenzeneboronic acid (1a) (M1)/styrene, resp. bis(trimethylsilyl) p-vinylbenzeneboronate (1b) (M1)/styrene were determined by means of boron analyses: 1a: r1=0,28±0,06 and r2=0,83±0,04 1b: r1=0,28±0,10 and r2=0,87±0,08 By cleavage of the trimethylsilyl groups, the 1b /styrene copolymers are smoothly transformed into 1a /styrene copolymers. The lithium, sodium, and potassium salts of some copolymers were prepared. The solution viscosities of the polymeric boronic acids in benzene/methanol mixtures and in dimethyl sulfoxide (DMSO) markedly depend on the boronic acid content. In benzene/methanol mixtures the preferential solvatation of the boronic acid groups by methanol can be ascertained. Further, the introduction of boronic acid groups in polystyr-enecorresponds with an increase of theglass transition temperature. The torsion pendulum measurements show that the pressure-molding of the polymers causes the formation of crosslinks, which are boronic acid anhydrides. These crosslinks can be cleaved by protic solvents.

Journal ArticleDOI
TL;DR: The pH-value and lactate concentration in connection with cell density proved to be important factors in the modification of the MPS distribution pattern.


Journal ArticleDOI
Egon Uhlig1, D. Linke1
TL;DR: In this paper, the influence of the solvatation of substituted 2,3-butanediones and their corresponding cations and anions may be described by the protonation constants cK 1n of their conjugated bases.
Abstract: Die Oxime und Dioxime der substituierten Butandione-(2,3) und die von ihnen abgeleiteten Kationen und Anionen lassen sich als Neutral-, Pseudoneutral- und Anionsauren klassifizieren. Ihre elektrolytische Dissoziation kann durch die Protonierungskonstanten cK1n der konjugierten Basen beschrieben werden. In Dioxan-Wasser-Mischungen steigen mit zunehmendem Dioxan-Gehalt die cK1n-Werte bei den Neutral- und Anionsauren stark, bei den Pseudoneutralsauren schwach an. Der Gang wird auf den Einflus der Dielektrizitatskonstante und auf die Anderung der Solvatation der Sauren und ihrer konjugierten Basen mit der Losungsmittelzusammensetzung zuruckgefuhrt. Die 1-Amino-butandion-(2,3)-oxime-(2) und die 1-Aminobutandioxime-(2,3) existieren in einer inneren Ammonium-oximat- und in einer Amin-oxim-Form. Die Verschiebung des Tautomeriegleichgewichtes nach der Seite der Amin-oxim-Form mit steigendem Dioxangehalt des Losungsmittels erklart den anomalen Gang in den cK1n-Werten dieser Verbindungen. On the Influence of the Solvent on the Acidity of Substituted 2,3-Butanedione Oximes The oximes and dioximes of substituted 2,3-butanediones and their corresponding cations and anions may be classified as neutral, pseudo-neutral, and anion acids. Their electrolytic dissociation may be described by the protonation constants cK1n of their conjugated bases. In dioxane-water mixtures with an increasing content of dioxane a strong increase of cK1n is observed for neutral and anion acids, but only a slight one for the pseudo-neutral acids. The change of cK1n is attributed to the influence of the dielectric constant and to differences in the solvatation of the acids and of their conjugated bases in mixtures with a different content of dioxane. In the case of the 1-amino-2,3-butanedione 2-oximes and of the 1-amino-2,3-butanedione dioximes, two tautomeric species are observed, the ammonium-oximates and the amine-oximes. The shift of the tautomery equilibrium to the amineoxime in solutions with a high content of dioxane causes an abnormal dependence of cK1n on the composition of the solvent.


Journal ArticleDOI
TL;DR: After repeated THAM administrations to rats of different ages, an enhancement of THAM accumulation in renal cortical slices was observed, except in newborns, which can be interpreted as a specific substrate stimulation of the organic base transport system.
Abstract: After repeated THAM administrations to rats of different ages, an enhancement of THAM accumulation in renal cortical slices was observed, except in newborns. This effect can be interpreted as a specific substrate stimulation of the organic base transport system.

Journal ArticleDOI
TL;DR: Alcian Blue proved to be a hemagglutinin specific for negatively charged receptors and provides indirect evidence for the spatial arrangement of erythrocyte receptor sites.