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Institution

University of Johannesburg

EducationJohannesburg, South Africa
About: University of Johannesburg is a education organization based out in Johannesburg, South Africa. It is known for research contribution in the topics: Population & Tourism. The organization has 8070 authors who have published 22749 publications receiving 329408 citations. The organization is also known as: UJ.


Papers
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Journal ArticleDOI
TL;DR: The developed Na-Alg-s-AgNPs@SiO2 nanohybrid has a potential to be used for various antibacterial applications in biotechnology and biomedical fields.

94 citations

Journal ArticleDOI
TL;DR: The dereplicated ethanolic extracts of Leonotisleonurus and Bulbine alooides showed the greatest anti-HIV potential in this study through inhibition of HIV-1 PR.

94 citations

Journal ArticleDOI
TL;DR: Findings suggest practitioner guidelines to support the mental health and wellbeing of parent carers should include addressing the parent’s self-perspective taking and skill for real time problem-solving.
Abstract: Parent carers of children with Autism Spectrum Disorder (ASD) often report increased levels of stress, depression, and anxiety. Unmet parent carer mental health needs pose a significant risk to the psychological, physical, and social well-being of the parents of the child affected by ASD and jeopardize the adaptive functioning of the family as well as the potential of the child affected by ASD. This systematic review identifies key qualities of interventions supporting the mental health of parent carers and proposes practitioner-parent carer support guidelines. A search of four databases (Medline, PubMed, PsycINFO, and Social Science Data) was conducted to identify studies that met the following criteria: (1) an intervention was delivered to parent carers of a child with ASD under the age of 18 years; (2) the research design allowed for a comparison on outcomes across groups; and (3) outcome measures of the parent carers’ mental health were used. A total of 23 studies met the inclusion criteria. A critical interpretive synthesis approach was used to produce an integrated conceptualization of the evidence. Findings suggest practitioner guidelines to support the mental health and wellbeing of parent carers should include addressing the parent’s self-perspective taking and skill for real time problem-solving.

94 citations

Journal ArticleDOI
Morad Aaboud, Alexander Kupco1, Samuel Webb2, Timo Dreyer3  +2977 moreInstitutions (217)
TL;DR: In this article, the efficiency of detecting b-hadrons was measured using a high purity sample of dileptonic top quark-antiquark pairs selected from the 36.1 fb$^{−1}$ of data collected by the ATLAS detector in 2015 and 2016 from proton-proton collisions produced by the Large Hadron Collider at a centre-of-mass energy of 13 $ TeV.
Abstract: The efficiency to identify jets containing b-hadrons (b-jets) is measured using a high purity sample of dileptonic top quark-antiquark pairs ( $ t\overline{t} $ ) selected from the 36.1 fb$^{−1}$ of data collected by the ATLAS detector in 2015 and 2016 from proton-proton collisions produced by the Large Hadron Collider at a centre-of-mass energy $ \sqrt{s}=13 $ TeV. Two methods are used to extract the efficiency from $ t\overline{t} $ events, a combinatorial likelihood approach and a tag-and-probe method. A boosted decision tree, not using b-tagging information, is used to select events in which two b-jets are present, which reduces the dominant uncertainty in the modelling of the flavour of the jets. The efficiency is extracted for jets in a transverse momentum range from 20 to 300 GeV, with data-to-simulation scale factors calculated by comparing the efficiency measured using collision data to that predicted by the simulation. The two methods give compatible results, and achieve a similar level of precision, measuring data-to-simulation scale factors close to unity with uncertainties ranging from 2% to 12% depending on the jet transverse momentum.

94 citations

Journal ArticleDOI
TL;DR: This review focuses on TGF-β and WNT signaling in cardiac fibrosis, ECM production, and myofibroblast transformation, and their mutual interaction, which have emerged as important factors involved in cardiac pathophysiology.
Abstract: Cardiac fibrosis describes the inappropriate proliferation of cardiac fibroblasts (CFs), leading to accumulation of extracellular matrix (ECM) proteins in the cardiac muscle, which is found in many pathophysiological heart conditions. A range of molecular components and cellular pathways, have been implicated in its pathogenesis. In this review, we focus on the TGF-β and WNT signaling pathways, and their mutual interaction, which have emerged as important factors involved in cardiac pathophysiology. The molecular and cellular processes involved in the initiation and progression of cardiac fibrosis are summarized. We focus on TGF-β and WNT signaling in cardiac fibrosis, ECM production, and myofibroblast transformation. Non-coding RNAs (ncRNAs) are one of the main players in the regulation of multiple pathways and cellular processes. MicroRNAs, long non-coding RNAs, and circular long non-coding RNAs can all interact with the TGF-β/WNT signaling axis to affect cardiac fibrosis. A better understanding of these processes may lead to new approaches for diagnosis and treatment of many cardiac conditions.

94 citations


Authors

Showing all 8414 results

NameH-indexPapersCitations
Vinod Kumar Gupta16571383484
Arnold B. Bakker135506103778
Trevor Vickey12887376664
Ketevi Assamagan12893477061
Diego Casadei12373369665
Michael R. Hamblin11789959533
E. Castaneda-Miranda11754556349
Xiaoming Li113193272445
Katharine Leney10845952547
M. Aurousseau10340344230
Mika Sillanpää96101944260
Sahal Yacoob8940825338
Evangelia Demerouti8523649228
Lehana Thabane8599436620
Sahal Yacoob8439935059
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023196
2022526
20213,152
20202,933
20192,706
20182,150