University of Johannesburg

About: University of Johannesburg is a education organization based out in Johannesburg, South Africa. It is known for research contribution in the topics: Population & Context (language use). The organization has 8070 authors who have published 22749 publications receiving 329408 citations. The organization is also known as: UJ.

Tourism and the Millennium Development Goals: perspectives beyond 2015

Abstract: As 2015 approaches, debates about the contribution to the United Nations Millennium Development Goals (UN MDGs) are growing in momentum. The aim of this review is to interrogate the potential contributions of tourism to the UN MDGs, specifically of poverty alleviation, and of how the relationship between tourism development and the UN MDGs has been framed in existing scholarship. It is argued that whilst the global tourism industry potentially can contribute to economic development goals in destination regions, its impacts are ambivalent so that there is a growing concern surrounding the local benefits of global tourism including support for realisation of the UN MDGs. To avert the risks in the Global South of tourism-led development, the industry needs to be clearly positioned as a potential tool for, not at the end of local, regional, national and global development agendas. Several promising research avenues for interrogating tourism impacts for UN MDGs are identified. Issues relating to greening of to...

Rapidity gap cross sections measured with the ATLAS detector in pp collisions at √ s =7 TeV

Abstract: Pseudorapidity gap distributions in proton-proton collisions at root s = 7 TeV are studied using a minimum bias data sample with an integrated luminosity of 7.1 mu b(-1). Cross sections are measured differentially in terms of Delta eta(F), the larger of the pseudorapidity regions extending to the limits of the ATLAS sensitivity, at eta = +/- 4.9, in which no final state particles are produced above a transverse momentum threshold p(T)(cut). The measurements span the region 0 Xp), enhanced by double dissociation (pp -> XY) where the invariant mass of the lighter of the two dissociation systems satisfies M-Y less than or similar to 7 GeV. The resulting cross section is ds sigma/d Delta eta(F) approximate to 1 mb for Delta eta(F) greater than or similar to 3. The large rapidity gap data are used to constrain the value of the Pomeron intercept appropriate to triple Regge models of soft diffraction. The cross section integrated over all gap sizes is compared with other LHC inelastic cross section measurements.

Photodynamic Therapy for Metastatic Melanoma Treatment: A Review.

Abstract: This review article is based on specifically targeted nanoparticles that have been used in the treatment of melanoma. According to the Skin Cancer Foundation, within 2017 an estimated 9730 people will die due to invasive melanoma. Conventional treatments for nonmalignant melanoma include surgery, chemotherapy, and radiation. For the treatment of metastatic melanoma, 3 therapeutic agents have been approved by the Food and Drug Administration: dacarbazine, recombinant interferon α-2b, and high-dose interleukin 2. Photodynamic therapy is an alternative therapy that activates a photosensitizer at a specific wavelength forming reactive oxygen species which in turn induces cell death; it is noninvasive with far less side effects when compared to conventional treatments. Nanoparticles are generally conjugated to photosynthetic drugs, since they are biocompatible, stabile, and durable, as well as have a high loading capacity, which improve either passive or active photosensitizer drug delivery to targeted cells. Therefore, various photosynthetic drugs and nanoparticle drug delivery systems specifically targeted for melanoma were analyzed in this review article in relation to either their passive or their active cellular uptake mechanisms in order to deduce the efficacy of photodynamic therapy treatment for metastatic melanoma which currently remains ongoing. The overall findings from this review concluded that no current photodynamic therapy studies have been performed in relation to active nanoparticle platform photosensitizer drug carrier systems for the treatment of metastatic melanoma, and so this type of research requires further investigation into developing a more efficient active nano-photosensitizer carrier smart drug that can be conjugated to specific cell surface receptors and combinative monoclonal antibodies so that a further enhanced and more efficient form of targeted photodynamic therapy for the treatment of metastatic melanoma can be established.

Standing on the shoulders of giants : notes on early positive psychology (psychofortology)

Abstract: Psychofortology is an alternative designation for positive psychology, and fortology (Latin fortis = strong) an antonym for pathology. The strengths paradigm has ancient origins. In this article br...