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Institution

University of Kentucky

EducationLexington, Kentucky, United States
About: University of Kentucky is a education organization based out in Lexington, Kentucky, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 43933 authors who have published 92195 publications receiving 3256087 citations. The organization is also known as: UK.


Papers
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Journal Article
TL;DR: Cloud as discussed by the authors models the ionization, chemical, and thermal state of material that may be exposed to an external radiation field or other source of heating, and predicts observables such as emission and absorption spectra.
Abstract: This is a summary of the 2013 release of the plasma simulation code Cloudy. Cloudy models the ionization, chemical, and thermal state of material that may be exposed to an external radiation field or other source of heating, and predicts observables such as emission and absorption spectra. It works in terms of elementary processes, so is not limited to any particular temperature or density regime. This paper summarizes advances made since the last major review in 1998. Much of the recent development has emphasized dusty molecular environments, improvements to the ionization/chemistry solvers, and how atomic and molecular data are used. We present two types of simulations to demonstrate the capability of the code. We consider a molecular cloud irradiated by an X-ray source such as an active nucleus and show how treating EUV recombination lines and the full SED affects the observed spectrum. A second example illustrates the very wide range of particle and radiation density that can be considered.

497 citations

Journal ArticleDOI
TL;DR: The results suggest that AD pathogenesis may involve the activation of oxidant-producing inflammatory enzyme systems, including nitric oxide synthase, as well as peroxynitrite scavenger systems.
Abstract: HPLC with electrochemical array detection (HPLC-ECD) was used to quantify 3,3'-dityrosine (diTyr) and 3-nitrotyrosine (3-NO2-Tyr) in four regions of the human brain that are differentially affected in Alzheimer's disease (AD). DiTyr and 3-NO2-Tyr levels were elevated consistently in the hippocampus and neocortical regions of the AD brain and in ventricular cerebrospinal fluid (VF), reaching quantities five- to eightfold greater than mean concentrations in brain and VF of cognitively normal subjects. Uric acid, a proposed peroxynitrite scavenger, was decreased globally in the AD brain and VF. The results suggest that AD pathogenesis may involve the activation of oxidant-producing inflammatory enzyme systems, including nitric oxide synthase.

497 citations

Journal ArticleDOI
TL;DR: Pre-emptive morphine infusions did not reduce the frequency of severe IVH, PVL, or death in ventilated preterm neonates, but intermittent boluses of open-label morphine were associated with an increased rate of the composite outcome.

497 citations

Journal ArticleDOI
Abstract: The agricultural household's discrete decision of whether to participate in coarse grain markets is separated here from the continuous decision of how much to sell or buy, conditional on participation. Failure to participate in markets results from high fixed transactions costs. A selectivity model endogenously switches households into alternative market participation states, correcting for bias caused by the exclusion of unobservable variables affecting both discrete and continuous decisions. Improved market information increases the probability of participation by sellers, while access to cereals-processing technology increases quantities transacted by both sellers and buyers, conditional on participation.

496 citations

Journal ArticleDOI
TL;DR: In this paper, the mean square error of prediction is proposed as a criterion for selecting variables, which utilizes the values of the predictor variables associated with the future observation and the magnitude of the estimated variance.
Abstract: The mean square error of prediction is proposed as a criterion for selecting variables. This criterion utilizes the values of the predictor variables associated with the future observation and the magnitude of the estimated variance. Mean square error is believed to be more meaningful than the commonly used criterion, the residual sum of squares.

496 citations


Authors

Showing all 44305 results

NameH-indexPapersCitations
Mark P. Mattson200980138033
Carlo M. Croce1981135189007
Charles A. Dinarello1901058139668
Richard A. Gibbs172889249708
Gang Chen1673372149819
David A. Bennett1671142109844
Carl W. Cotman165809105323
Rodney S. Ruoff164666194902
David Tilman158340149473
David Cella1561258106402
Richard E. Smalley153494111117
Deepak L. Bhatt1491973114652
Kevin Murphy146728120475
Jian Yang1421818111166
Thomas J. Smith1401775113919
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023108
2022532
20214,329
20204,216
20193,965
20183,605