University of Kentucky

About: University of Kentucky is a education organization based out in Lexington, Kentucky, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 43933 authors who have published 92195 publications receiving 3256087 citations. The organization is also known as: UK.

Volunteered Geographic Information and Crowdsourcing Disaster Relief: A Case Study of the Haitian Earthquake

Abstract: This paper outlines the ways in which information technologies (ITs) were used in the Haiti relief effort, especially with respect to web-based mapping services. Although there were numerous ways in which this took place, this paper focuses on four in particular: CrisisCamp Haiti, OpenStreetMap, Ushahidi, and GeoCommons. This analysis demonstrates that ITs were a key means through which individuals could make a tangible difference in the work of relief and aid agencies without actually being physically present in Haiti. While not without problems, this effort nevertheless represents a remarkable example of the power and crowdsourced online mapping and the potential for new avenues of interaction between physically distant places that vary tremendously.

Function and Regulation of Yeast Hexose Transporters

Abstract: Glucose, the most abundant monosaccharide in nature, is the principal carbon and energy source for nearly all cells. The first, and rate-limiting, step of glucose metabolism is its transport across the plasma membrane. In cells of many organisms glucose ensures its own efficient metabolism by serving as an environmental stimulus that regulates the quantity, types, and activity of glucose transporters, both at the transcriptional and posttranslational levels. This is most apparent in the baker’s yeast Saccharomyces cerevisiae, which has 20 genes encoding known or likely glucose transporters, each of which is known or likely to have a different affinity for glucose. The expression and function of most of these HXT genes is regulated by different levels of glucose. This review focuses on the mechanisms S. cerevisiae and a few other fungal species utilize for sensing the level of glucose and transmitting this information to the nucleus to alter HXT gene expression. One mechanism represses transcription of some HXT genes when glucose levels are high and works through the Mig1 transcriptional repressor, whose function is regulated by the Snf1-Snf4 protein kinase and Reg1-Glc7 protein phosphatase. Another pathway induces HXT expression in response to glucose and employs the Rgt1 transcriptional repressor, a ubiquitin ligase protein complex (SCFGrr1) that regulates Rgt1 function, and two glucose sensors in the membrane (Snf3 and Rgt2) that bind glucose and generate the intracellular signal to which Rgt1 responds. These two regulatory pathways collaborate with other, less well-understood, pathways to ensure that yeast cells express the glucose transporters best suited for the amount of glucose available.

Aggression and Antisocial Behavior in Youth

Abstract: This chapter reviews the literatures on the normative development of antisocial behavior and how individual differences in antisocial behavior develop across the life span. The literature can be integrated with a model that includes biological (genetic, neural, and temperament) and socialization (parenting, peer, academic, and neighborhood) factors in antisocial development. These factors operate as main effects that cumulate, interaction effects that moderate each other, and developmental processes that mediate each other and transact across time. Social information processing factors (e.g., selective attention, hostile attributional bias, incompetent social problem-solving skills, and response evaluation biases) have been found to mediate these effects. Interventions that address these factors have proven partially successful in preventing antisocial development and may be targets for future efforts. Keywords: biological factors; individual differences; intervention; normative development; social information processing; socialization factors

Antecedents to Customer Expectations for Service Recovery

Abstract: Selected antecedents of customers’ service recovery expectations are considered in this study. A conceptual model is proposed in which customer perceptions of service quality, customer satisfaction, and customer organizational commitment function as antecedents to service recovery expectations. The proposed model was tested with covariance structure analysis. The results support the hypothesized relationships, suggesting that service quality and customer organizational commitment have direct effects on customer service recovery expectations and that customer satisfaction has an indirect effect on service recovery expectations.

A Resource‐Based View of Strategic IT Alignment: How Knowledge Sharing Creates Competitive Advantage

Abstract: A critical decision problem for top management, and the focus of this study, is whether the CEO (chief executive officer) and CIO (chief information officer) should commit their time to formal planning with the expectation of producing an information technology (IT)-based competitive advantage. Using the perspective of the resource-based view, a model is presented that examines how strategic IT alignment can produce enhanced organizational strategies that yield competitive advantage. One hundred sixty-one CIOs provided data using a postal survey. Results supported seven of the eight hypotheses. They showed that information intensity is an important antecedent to strategic IT alignment, that strategic IT alignment is best explained by multiple constructs which operationalize both process and content measures, and that alignment between the IT plan and the business plan is significantly related to the use of IT for competitive advantage. Study results raise questions about the effect of CEO participation, which appears to be the weak link in the process, and also about the perception of the CIO on the importance of CEO involvement. The paper contributes to our understanding of how knowledge sharing in the alignment process contributes to the creation of superior organizational strategies, provides a framework of the alignment-performance relationship, and furnishes several new constructs.