University of Konstanz

About: University of Konstanz is a education organization based out in Konstanz, Baden-Württemberg, Germany. It is known for research contribution in the topics: Population & Visualization. The organization has 12115 authors who have published 27401 publications receiving 951162 citations. The organization is also known as: University of Constance & Universität Konstanz.

New treatments in neurorehabilitation founded on basic research

Abstract: Recent discoveries about how the central nervous system responds to injury and how patients reacquire lost behaviours by training have yielded promising new therapies for neurorehabilitation. Until recently, this field had been largely static, but the current melding of basic behavioural science with neuroscience promises entirely new approaches to improving behavioural, perceptual and cognitive capabilities after neurological damage. Studies of phenomena such as cortical reorganization after a lesion, central nervous system repair, and the substantial enhancement of extremity use and linguistic function by behavioural therapy, support this emerging view. The ongoing changes in rehabilitation strategies might well amount to an impending paradigm shift in this field.

k.p theory for two-dimensional transition metal dichalcogenide semiconductors

Abstract: We present $\mathbf{k}\cdotp\mathbf{p}$ Hamiltonians parametrised by {\it ab initio} density functional theory calculations to describe the dispersion of the valence and conduction bands at their extrema (the $K$, $Q$, $\Gamma$, and $M$ points of the hexagonal Brillouin zone) in atomic crystals of semiconducting monolayer transition metal dichalcogenides. We review the parametrisation of the essential parts of the $\mathbf{k}\cdotp\mathbf{p}$ Hamiltonians for MoS$_2$, MoSe$_2$, WS$_2$, and WSe$_2$, including the spin-splitting and spin-polarisation of the bands, and we discuss the vibrational properties of these materials. We then use $\mathbf{k}\cdotp\mathbf{p}$ theory to analyse optical transitions in two-dimensional transition metal dichalcogenides over a broad spectral range that covers the Van Hove singularities in the band structure (the $M$ points). We also discuss the visualisation of scanning tunnelling microscopy maps.

Job characteristics and off-job activities as predictors of need for recovery, well-being, and fatigue.

Abstract: Two empirical studies examined need for recovery (i.e., a person's desire to be temporarily relieved from demands in order to restore his or her resources) as a mediator in the relationship between poor job characteristics (high job demands, low job control) and high off-job demands, on the one hand, and fatigue and poor individual well-being, on the other hand. Multilevel data from a daily survey study in the health service sector (Study 1) showed that high job demands, low job control, and unfavorable off-job activities predicted a high need for recovery. Need for recovery in turn was negatively related to individual well-being. A large-scale survey with a representative sample of the Dutch working population (Study 2) confirmed these findings for fatigue. In both studies, need for recovery mediated the effects of job characteristics and off-job activities on fatigue and poor well-being, respectively.

Toll-Like Receptor 2 Suppresses Immunity against Candida albicans through Induction of IL-10 and Regulatory T Cells

Abstract: Toll-like receptor (TLR) 2 and TLR4 play a pivotal role in recognition of Candida albicans. We demonstrate that TLR2(-/-) mice are more resistant to disseminated Candida infection, and this is associated with increased chemotaxis and enhanced candidacidal capacity of TLR2(-/-) macrophages. Although production of the proinflammatory cytokines TNF, IL-1alpha, and IL-1beta is normal, IL-10 release is severely impaired in the TLR2(-/-) mice. This is accompanied by a 50% decrease in the CD4+CD25+ regulatory T (Treg) cell population in TLR2(-/-) mice. In vitro studies confirmed that enhanced survival of Treg cells was induced by TLR2 agonists. The deleterious role of Treg cells on the innate immune response during disseminated candidiasis was underscored by the improved resistance to this infection after depletion of Treg cells. In conclusion, C. albicans induces immunosuppression through TLR2-derived signals that mediate increased IL-10 production and survival of Treg cells. This represents a novel mechanism in the pathogenesis of fungal infections.

Transactional Information Systems: Theory, Algorithms, and the Practice of Concurrency Control and Recovery

Abstract: Transactional Information Systems is the long-awaited, comprehensive work from leading scientists in the transaction processing field. Weikum and Vossen begin with a broad look at the role of transactional technology in today's economic and scientific endeavors, then delve into critical issues faced by all practitioners, presenting today's most effective techniques for controlling concurrent access by multiple clients, recovering from system failures, and coordinating distributed transactions. The authors emphasize formal models that are easily applied across fields, that promise to remain valid as current technologies evolve, and that lend themselves to generalization and extension in the development of new classes of network-centric, functionally rich applications. This book's purpose and achievement is the presentation of the foundations of transactional systems as well as the practical aspects of the field what will help you meet today's challenges. * Provides the most advanced coverage of the topic available anywhere--along with the database background required for you to make full use of this material. * Explores transaction processing both generically as a broadly applicable set of information technology practices and specifically as a group of techniques for meeting the goals of your enterprise. * Contains information essential to developers of Web-based e-Commerce functionality--and a wide range of more "traditional" applications. * Details the algorithms underlying core transaction processing functionality. Table of Contents PART ONE - BACKGROUND AND MOTIVATION Chapter 1 What Is It All About? Chapter 2 Computational Models PART TWO - CONCURRENCY CONTROL Chapter 3 Concurrency Control: Notions of Correctness for the Page Model Chapter 4 Concurrency Control Algorithms Chapter 5 Multiversion Concurrency Control Chapter 6 Concurrency Control on Objects: Notions of Correctness Chapter 7 Concurrency Control Algorithms on Objects Chapter 8 Concurrency Control on Relational Databases Chapter 9 Concurrency Control on Search Structures Chapter 10 Implementation and Pragmatic Issues PART THREE - RECOVERY Chapter 11 Transaction Recovery Chapter 12 Crash Recovery: Notion of Correctness Chapter 13 Page Model Crash Recovery Algorithms Chapter 14 Object Model Crash Recovery Chapter 15 Special Issues of Recovery Chapter 16 Media Recovery Chapter 17 Application Recovery PART FOUR - COORDINATION OF DISTRIBUTED TRANSACTIONS Chapter 18 Distributed Concurrency Control Chapter 19 Distributed Transaction Recovery PART FIVE - APPLICATIONS AND FUTURE PERSPECTIVES Chapter 20 What Is Next?