University of Konstanz

About: University of Konstanz is a education organization based out in Konstanz, Baden-Württemberg, Germany. It is known for research contribution in the topics: Population & Membrane. The organization has 12115 authors who have published 27401 publications receiving 951162 citations. The organization is also known as: University of Constance & Universität Konstanz.

Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor

Abstract: Prenatal exposure to maternal stress can have lifelong implications for psychological function, such as behavioral problems and even the development of mental illness. Previous research suggests that this is due to transgenerational epigenetic programming of genes operating in the hypothalamic–pituitary–adrenal axis, such as the glucocorticoid receptor (GR). However, it is not known whether intrauterine exposure to maternal stress affects the epigenetic state of these genes beyond infancy. Here, we analyze the methylation status of the GR gene in mothers and their children, at 10–19 years after birth. We combine these data with a retrospective evaluation of maternal exposure to intimate partner violence (IPV). Methylation of the mother's GR gene was not affected by IPV. For the first time, we show that methylation status of the GR gene of adolescent children is influenced by their mother's experience of IPV during pregnancy. As these sustained epigenetic modifications are established in utero, we consider this to be a plausible mechanism by which prenatal stress may program adult psychosocial function.

Processes involved in formation and emission of methane in rice paddies

Abstract: The seasonal change of the rates of production and emission of methane were determined under in-situ conditions in an Italian rice paddy in 1985 and 1986. The contribution to total emission of CH4 of plant-mediated transport, ebullition, and diffusion through the flooding water was quantified by cutting the plants and by trapping emerging gas bubbles with funnels. Both production and emission of CH4 increased during the season and reached a maximum in August. However, the numbers of methanogenic bacteria did not change. As the rice plants grew and the contribution of plant-mediated CH4 emission increased, the percentage of the produced CH4 which was reoxidized and thus, was not emitted, also increased. At its maximum, about 300 ml CH4 were produced per m2 per hour. However, only about 6% were emitted and this was by about 96% via plant-mediated transport. Radiotracer experiments showed that CH, was produced from H2/CO2. (30–50%) and from acetate. The pool concentration of acetate was in the range of 6–10 mM. The turnover time of acetate was 12–16 h. Part of the acetate pool appeared to be not available for production of CH4 or CO2

Challenges in Visual Data Analysis

Abstract: In today’s applications data is produced at unprecedented rates. While the capacity to collect and store new data grows rapidly, the ability to analyze these data volumes increases at much lower pace. This gap leads to new challenges in the analysis process, since analysts, decision makers, engineers, or emergency response teams depend on information "concealed" in the data. The emerging field of visual analytics focuses on handling massive, heterogenous, and dynamic volumes of information through integration of human judgement by means of visual representations and interaction techniques in the analysis process. Furthermore, it is the combination of related research areas including visualization, data mining, and statistics that turns visual analytics into a promising field of research. This paper aims at providing an overview of visual analytics, its scope and concepts, and details the most important technical research challenges in the field.

Staying Well and Engaged When Demands Are High: The Role of Psychological Detachment.

Abstract: The authors of this study examined the relation between job demands and psychological detachment from work during off-job time (i.e., mentally switching off) with psychological well-being and work engagement. They hypothesized that high job demands and low levels of psychological detachment predict poor well-being and low work engagement. They proposed that psychological detachment buffers the negative impact of high job demands on well-being and work engagement. A longitudinal study (12-month time lag) with 309 human service employees showed that high job demands predicted emotional exhaustion, psychosomatic complaints, and low work engagement over time. Psychological detachment from work during off-job time predicted emotional exhaustion and buffered the relation between job demands and an increase in psychosomatic complaints and between job demands and a decrease in work engagement. The findings of this study suggest that psychological detachment from work during off-job time is an important factor that helps to protect employee well-being and work engagement.

International Norms and Domestic Politics: Bridging the Rationalist—Constructivist Divide

Abstract: In recent years, students of regimes and norms have paid greater attention to domestic politics. Both liberals and constructivists are `unpacking' the state in ways that further our understanding of how international norms work their effects in the domestic arena. A crucial next step is for adherents of these two schools to engage in dialogue. This article contributes to such an enterprise by developing scope conditions that predict when norms will have the constraining or constitutive effects favored, respectively, by liberals and constructivists. I make a distinction between compliance with norms and the diffusion mechanisms empowering them domestically, explaining variance in the latter with an institutional argument that captures key dynamics — rationalist or social constructivist — portrayed in other prominent accounts. The argument is illustrated by considering the domestic impact of norms embedded in the European human rights regime.