Institution
University of Lincoln
Education•Lincoln, Lincolnshire, United Kingdom•
About: University of Lincoln is a education organization based out in Lincoln, Lincolnshire, United Kingdom. It is known for research contribution in the topics: Population & Context (language use). The organization has 2341 authors who have published 7025 publications receiving 124797 citations.
Papers published on a yearly basis
Papers
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TL;DR: In this paper, the authors show how a global community is responding to the challenges of tropical ecosystem research with diverse teams measuring forests tree-by-tree in thousands of long-term plots.
66 citations
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TL;DR: This work reexamines seeded simulation results for NaCl nucleation from a supersaturated aqueous solution at 298.15 K and 1 bar pressure and presents a linear regression approach for analyzing seeded simulation data that provides both nucleation rates and uncertainty estimates.
Abstract: This work reexamines seeded simulation results for NaCl nucleation from a supersaturated aqueous solution at 298.15 K and 1 bar pressure. We present a linear regression approach for analyzing seeded simulation data that provides both nucleation rates and uncertainty estimates. Our results show that rates obtained from seeded simulations rely critically on a precise driving force for the model system. The driving force vs. solute concentration curve need not exactly reproduce that of the real system, but it should accurately describe the thermodynamic properties of the model system. We also show that rate estimates depend strongly on the nucleus size metric. We show that the rate estimates systematically increase as more stringent local order parameters are used to count members of a cluster and provide tentative suggestions for appropriate clustering criteria.
66 citations
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TL;DR: Ruxolitinib was associated with a nonsignificant trend towards improved PV‐related symptoms versus hydroxy carbamide, although an unexpectedly large proportion of patients who maintained their hydroxycarbamide dose reported symptom improvement.
Abstract: Summary
The randomized, double-blind, double-dummy, phase 3b RELIEF trial evaluated polycythaemia vera (PV)-related symptoms in patients who were well controlled with a stable dose of hydroxycarbamide (also termed hydroxyurea) but reported PV-related symptoms. Patients were randomized 1:1 to ruxolitinib 10 mg BID (n = 54) or hydroxycarbamide (prerandomization dose/schedule; n = 56); crossover to ruxolitinib was permitted after Week 16. The primary endpoint, ≥50% improvement from baseline in myeloproliferative neoplasm -symptom assessment form total symptom score cytokine symptom cluster (TSS-C; sum of tiredness, itching, muscle aches, night sweats, and sweats while awake) at Week 16, was achieved by 43·4% vs. 29·6% of ruxolitinib- and hydroxycarbamide-treated patients, respectively (odds ratio, 1·82; 95% confidence interval, 0·82–4·04; P = 0·139). The primary endpoint was achieved by 34% of a subgroup who maintained their hydroxycarbamide dose from baseline to Weeks 13–16. In a post hoc analysis, the primary endpoint was achieved by more patients with stable screening-to-baseline TSS-C scores (ratio ≤ 2) receiving ruxolitinib than hydroxycarbamide (47·4% vs. 25·0%; P = 0·0346). Ruxolitinib treatment after unblinding was associated with continued symptom score improvements. Adverse events were primarily grades 1/2 with no unexpected safety signals. Ruxolitinib was associated with a nonsignificant trend towards improved PV-related symptoms versus hydroxycarbamide, although an unexpectedly large proportion of patients who maintained their hydroxycarbamide dose reported symptom improvement.
66 citations
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University of Sheffield1, Aberystwyth University2, University of Bristol3, University of Leeds4, University Centre in Svalbard5, University of Utah6, Liverpool John Moores University7, University of Sydney8, Brown University9, Aarhus University10, University of Tromsø11, University of Lincoln12, University of Michigan13, University of Potsdam14, Free University of Berlin15, Geological Survey of Denmark and Greenland16
TL;DR: In this article, the authors combine field-spectroscopy with a radiative-transfer model, supervised classification of unmanned aerial vehicle (UAV) and satellite remote-sensing data, and runoff modelling to calculate the biologically driven ice surface ablation.
Abstract: . Melting of the Greenland Ice Sheet (GrIS) is the largest
single contributor to eustatic sea level and is amplified by the growth
of pigmented algae on the ice surface, which increases solar radiation
absorption. This biological albedo-reducing effect and its impact upon sea
level rise has not previously been quantified. Here, we combine field
spectroscopy with a radiative-transfer model, supervised classification of
unmanned aerial vehicle (UAV) and satellite remote-sensing data, and runoff modelling to calculate
biologically driven ice surface ablation. We demonstrate that algal growth
led to an additional 4.4–6.0 Gt of runoff from bare ice in the
south-western sector of the GrIS in summer 2017, representing 10 %–13 %
of the total. In localized patches with high biomass accumulation, algae
accelerated melting by up to 26.15±3.77 % (standard error, SE). The year 2017
was a high-albedo year, so we also extended our analysis to the particularly low-albedo 2016 melt season. The runoff from the south-western bare-ice zone attributed to algae was much higher in 2016 at 8.8–12.2 Gt, although the
proportion of the total runoff contributed by algae was similar at 9 %–13 %. Across a 10 000 km 2 area around our field site, algae covered
similar proportions of the exposed bare ice zone in both years (57.99 %
in 2016 and 58.89 % in 2017), but more of the algal ice was classed as
“high biomass” in 2016 (8.35 %) than 2017 (2.54 %). This interannual
comparison demonstrates a positive feedback where more widespread, higher-biomass algal blooms are expected to form in high-melt years where the
winter snowpack retreats further and earlier, providing a larger area for bloom
development and also enhancing the provision of nutrients and liquid water
liberated from melting ice. Our analysis confirms the importance of this
biological albedo feedback and that its omission from predictive models
leads to the systematic underestimation of Greenland's future sea level
contribution, especially because both the bare-ice zones available for algal
colonization and the length of the biological growth season are set to
expand in the future.
65 citations
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Pacific Marine Environmental Laboratory1, University of Alaska Fairbanks2, Massachusetts Institute of Technology3, University of Lincoln4, Alfred Wegener Institute for Polar and Marine Research5, Pukyong National University6, Niigata University7, Finnish Meteorological Institute8, University of Washington9
TL;DR: In this article, the authors investigated the role of sea ice loss in Arctic/midlatitude weather linkages, and found that sea-ice loss alone has played only a secondary role in the Arctic weather linkage, while the full influence of Arctic amplification remains uncertain.
Abstract: Pronounced changes in the Arctic environment add a new potential driver of anomalous weather patterns in midlatitudes that affect billions of people. Recent studies of these Arctic/midlatitude weather linkages, however, state inconsistent conclusions. A source of uncertainty arises from the chaotic nature of the atmosphere. Thermodynamic forcing by a rapidly warming Arctic contributes to weather events through changing surface heat fluxes and large-scale temperature and pressure gradients. But internal shifts in atmospheric dynamics — the variability of the location, strength, and character of the jet stream, blocking, and stratospheric polar vortex (SPV) — obscure the direct causes and effects. It is important to understand these associated processes to differentiate Arctic-forced variability from natural variability. For example in early winter, reduced Barents/Kara Seas sea-ice coverage may reinforce existing atmospheric teleconnections between the North Atlantic/Arctic and central Asia, and affect downstream weather in East Asia. Reduced sea ice in the Chukchi Sea can amplify atmospheric ridging of high pressure near Alaska, influencing downstream weather across North America. In late winter southward displacement of the SPV, coupled to the troposphere, leads to weather extremes in Eurasia and North America. Combined tropical and sea ice conditions can modulate the variability of the SPV. Observational evidence for Arctic/midlatitude weather linkages continues to accumulate, along with understanding of connections with pre-existing climate states. Relative to natural atmospheric variability, sea-ice loss alone has played a secondary role in Arctic/midlatitude weather linkages; the full influence of Arctic amplification remains uncertain.
65 citations
Authors
Showing all 2452 results
Name | H-index | Papers | Citations |
---|---|---|---|
David R. Williams | 178 | 2034 | 138789 |
David Scott | 124 | 1561 | 82554 |
Hugh S. Markus | 118 | 606 | 55614 |
Timothy E. Hewett | 116 | 531 | 49310 |
Wei Zhang | 96 | 1404 | 43392 |
Matthew Hall | 75 | 827 | 24352 |
Matthew C. Walker | 73 | 443 | 16373 |
James F. Meschia | 71 | 401 | 28037 |
Mark G. Macklin | 69 | 268 | 13066 |
John N. Lester | 66 | 349 | 19014 |
Christine J Nicol | 61 | 268 | 10689 |
Lei Shu | 59 | 598 | 13601 |
Frank Tanser | 54 | 231 | 17555 |
Simon Parsons | 54 | 462 | 15069 |
Christopher D. Anderson | 54 | 393 | 10523 |