University of Lincoln

About: University of Lincoln is a education organization based out in Lincoln, Lincolnshire, United Kingdom. It is known for research contribution in the topics: Population & Higher education. The organization has 2341 authors who have published 7025 publications receiving 124797 citations.

Late bloomers and baby boomers: ecological drivers of longevity in squamates and the tuatara

Abstract: Aim Longevity is an important life-history trait, directly linked to the core attributes of fitness (reproduction and survival), yet large-scale comparative studies quantifying its implications for the ecology and life history of ectotherms are scarce. We tested the allometry of longevity in squamates and the tuatara, and determined how longevity is related to key environmental characteristics and lifehistory traits. Predictions based on life-history theory are expected to hold true for ectotherms, similarly to mammals and birds. Location World-wide. Methods We assembled from the literature a dataset of the maximum longevities of more than a thousand squamate species, representing c. 10% of their known species diversity, their phylogenetic relationships and multiple life-history and ecological variables. Correcting for phylogeny, we modelled the link between squamate longevity and both key life-history traits, such as body mass and age at first reproduction, and important environmental factors, such as latitude and primary productivity within species distributional ranges. Results Large-bodied species live for longer than small ones, but body size explains far less of the variance in longevity than it does in mammals and birds. Accounting for body size, squamate brood frequency is negatively correlated with longevity, while age at first reproduction is positively correlated with longevity. This points to a continuum of slow-to-fast life-history strategies. Squamates in high latitudes and cold regions live for longer, probably because a shorter season of activity translates to slower development, older age at first reproduction and hence to increased longevity. Individuals live longer in captivity than in the wild. Herbivorous and omnivorous squamates live for longer than carnivorous ones. We postulate that low-quality nutrition reduces growth rates, promotes a relative decline in reproductive rates and thus prolongs life.

Stormy geomorphology: geomorphic contributions in an age of climate extremes

Abstract: The increasing frequency and/or severity of extreme climate events are becoming increasingly apparent over multi‐decadal timescales at the global scale, albeit with relatively low scientific confidence. At the regional scale, scientific confidence in the future trends of extreme event likelihood is stronger, although the trends are spatially variable. Confidence in these extreme climate risks is muddied by the confounding effects of internal landscape system dynamics and external forcing factors such as changes in land use and river and coastal engineering. Geomorphology is a critical discipline in disentangling climate change impacts from other controlling factors, thereby contributing to debates over societal adaptation to extreme events. We review four main geomorphic contributions to flood and storm science. First, we show how palaeogeomorphological and current process studies can extend the historical flood record while also unraveling the complex interactions between internal geomorphic dynamics, human impacts and changes in climate regimes. A key outcome will be improved quantification of flood probabilities and the hazard dimension of flood risk. Second, we present evidence showing how antecedent geomorphological and climate parameters can alter the risk and magnitude of landscape change caused by extreme events. Third, we show that geomorphic processes can both mediate and increase the geomorphological impacts of extreme events, influencing societal risk. Fourthly, we show the potential of managing flood and storm risk through the geomorphic system, both near‐term (next 50 years) and longer‐term. We recommend that key methods of managing flooding and erosion will be more effective if risk assessments include palaeodata, if geomorphological science is used to underpin nature‐based management approaches, and if land‐use management addresses changes in geomorphic process regimes that extreme events can trigger. We argue that adopting geomorphologically‐grounded adaptation strategies will enable society to develop more resilient, less vulnerable socio‐geomorphological systems fit for an age of climate extremes.

An analysis of legal highs—do they contain what it says on the tin?

Abstract: In recent years the availability of so called legal highs over the internet has hugely increased Numerous online legal high retailers market a broad variety of products which are advertised as research chemicals, bath salts or plant food although clearly intended for human consumption as recreational drug replacements No guidelines exist as to what is sold and in what purity Consumers are led to believe that purchased goods are entirely legal In this study several legal high products were purchased and analysed for their content The powdered products were screened with ATR-FTIR followed by GC-MS analysis of methanol extracts Spectra were compared to reference standards and the NIST library Results showed that 6 out of 7 products did not contain the advertised active ingredient Moreover, five samples contained the controlled substances benzylpiperazine and 1-[3-(trifluoromethyl)phenyl]piperazine combined with caffeine

A review of the mitigation of deposition and emission problems during biomass combustion through washing pre-treatment

Abstract: Pre-treatment of biomass via washing has shown to reduce the ash deposition and air-borne emissions. Particle size and temperature are important parameters to consider when washing biomass. Washing removes the problematic chemical species like K Na, Ca, Mg, Fe, Cl, S and P from the biomass. Hot water washing improves the removal efficiency of these metals, therefore increasing the ash melting temperatures. Removal of S and Cl reduce acid gases formation and hence corrosion in boilers and associated environmental impact.

ATRX Dysfunction Induces Replication Defects in Primary Mouse Cells

Abstract: The chromatin remodeling protein ATRX, which targets tandem repetitive DNA, has been shown to be required for expression of the alpha globin genes, for proliferation of a variety of cellular progenitors, for chromosome congression and for the maintenance of telomeres. Mutations in ATRX have recently been identified in tumours which maintain their telomeres by a telomerase independent pathway involving homologous recombination thought to be triggered by DNA damage. It is as yet unknown whether there is a central underlying mechanism associated with ATRX dysfunction which can explain the numerous cellular phenomena observed. There is, however, growing evidence for its role in the replication of various repetitive DNA templates which are thought to have a propensity to form secondary structures. Using a mouse knockout model we demonstrate that ATRX plays a direct role in facilitating DNA replication. Ablation of ATRX alone, although leading to a DNA damage response at telomeres, is not sufficient to trigger the alternative lengthening of telomere pathway in mouse embryonic stem cells.