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Institution

University of Lisbon

EducationLisbon, Lisboa, Portugal
About: University of Lisbon is a education organization based out in Lisbon, Lisboa, Portugal. It is known for research contribution in the topics: Population & Context (language use). The organization has 19122 authors who have published 48503 publications receiving 1102623 citations. The organization is also known as: Universidade de Lisboa & Lisbon University.


Papers
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Journal ArticleDOI
TL;DR: Evidence that the Williams syndrome transcription factor (WSTF) is targeted to replication foci through direct interaction with the DNA clamp PCNA is provided and it is proposed that the WSTF–ISWI complex has a role in the maintenance of chromatin structures during DNA replication.
Abstract: The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci

198 citations

Journal ArticleDOI
TL;DR: In this paper, it was shown that every hyperbolic measure invariant under a C 1+fi difieomorphism of a smooth Riemannian manifold possesses asymptotically "almost" local product structure, i.e., its density can be approximated by the product of the densities on stable and unstable manifolds up to small exponentials.
Abstract: We prove that every hyperbolic measure invariant under a C 1+fi difieomorphism of a smooth Riemannian manifold possesses asymptotically \almost" local product structure, i.e., its density can be approximated by the product of the densities on stable and unstable manifolds up to small exponentials. This has not been known even for measures supported on locally maximal hyperbolic sets. Using this property of hyperbolic measures we prove the long-standing Eckmann-Ruelle conjecture in dimension theory of smooth dynamical systems: the pointwise dimension of every hyperbolic measure invariant under a C 1+fi difieomorphism exists almost everywhere. This implies the crucial fact that virtually all the characteristics of dimension type of the measure (including the Hausdorfi dimension, box dimension, and information dimension) coincide. This provides the rigorous mathematical justiflcation of the concept of fractal dimension for hyperbolic measures.

198 citations

Journal ArticleDOI
TL;DR: It is shown that there is a statistically significant relationship between fire and same-summer droughts in most regions, while antecedent climate conditions play a relatively minor role, except in few specific eco-regions.
Abstract: Summer fires frequently rage across Mediterranean Europe, often intensified by high temperatures and droughts. According to the state-of-the-art regional fire risk projections, in forthcoming decades climate effects are expected to become stronger and possibly overcome fire prevention efforts. However, significant uncertainties exist and the direct effect of climate change in regulating fuel moisture (e.g. warmer conditions increasing fuel dryness) could be counterbalanced by the indirect effects on fuel structure (e.g. warmer conditions limiting fuel amount), affecting the transition between climate-driven and fuel-limited fire regimes as temperatures increase. Here we analyse and model the impact of coincident drought and antecedent wet conditions (proxy for the climatic factor influencing total fuel and fine fuel structure) on the summer Burned Area (BA) across all eco-regions in Mediterranean Europe. This approach allows BA to be linked to the key drivers of fire in the region. We show a statistically significant relationship between fire and same-summer droughts in most regions, while antecedent climate conditions play a relatively minor role, except in few specific eco-regions. The presented models for individual eco-regions provide insights on the impacts of climate variability on BA, and appear to be promising for developing a seasonal forecast system supporting fire management strategies.

198 citations

Journal ArticleDOI
N. Galamba1
TL;DR: The present results restore a molecular view where the slower translational and reorientational dynamics of water near hydrophobic groups has a structural equivalent resembling water at low temperatures.
Abstract: The structure of water in the hydration shells of small hydrophobic solutes was investigated through molecular dynamics. The results show that a subset of water molecules in the first hydration shell of a nonpolar solute have a significantly enhanced tetrahedrality and a slightly larger number of hydrogen bonds, relative to the molecules in water at room temperature, consistent with the experimentally observed negative excess entropy and increased heat capacity of hydrophobic solutions at room temperature. This ordering results from the rearrangement of a small number of water molecules near the nonpolar solutes that occupy one to two vertices of the enhanced water tetrahedra. Although this structuring is not nearly like that often associated with a literal interpretation of the term “iceberg” in the Frank and Evans iceberg model, it does support a moderate interpretation of this model. Thus, the tetrahedral orientational order of this ensemble of water molecules is comparable to that of liquid water at ∼...

198 citations

Journal ArticleDOI
TL;DR: This paper examines a methodology for computing the probability of structural failure by combining neural networks (NN) and Monte Carlo simulation (MCS), making use of the capability of a NN to approximate a function for reproducing structural behavior, allowing the computation of performance measures at a much lower cost.

198 citations


Authors

Showing all 19716 results

NameH-indexPapersCitations
Joao Seixas1531538115070
A. Gomes1501862113951
Marco Costa1461458105096
António Amorim136147796519
Osamu Jinnouchi13588586104
P. Verdier133111183862
Andy Haas132109687742
Wendy Taylor131125289457
Steve McMahon13087878763
Timothy Andeen129106977593
Heather Gray12996680970
Filipe Veloso12888775496
Nuno Filipe Castro12896076945
Oliver Stelzer-Chilton128114179154
Isabel Marian Trigger12897477594
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023247
2022828
20214,521
20204,517
20193,810
20183,617