Institution
University of Lorraine
Education•Nancy, France•
About: University of Lorraine is a education organization based out in Nancy, France. It is known for research contribution in the topics: Population & Nonlinear system. The organization has 11942 authors who have published 25010 publications receiving 425227 citations. The organization is also known as: Lorraine University.
Papers published on a yearly basis
Papers
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University of Leeds1, University of Edinburgh2, University College London3, University of Exeter4, Imperial College London5, National University of Saint Anthony the Abbot in Cuzco6, Universidad Autónoma Gabriel René Moreno7, National Institute of Amazonian Research8, Universidade do Estado de Mato Grosso9, Universidade Federal do Acre10, University of Los Andes11, University of Washington12, Environmental Change Institute13, Centre national de la recherche scientifique14, Museu Paraense Emílio Goeldi15, Lancaster University16, University of Lorraine17, Universidad Nacional de la Amazonía Peruana18, Smithsonian Institution19, University of Montpellier20, James Cook University21, Wageningen University and Research Centre22, Agro ParisTech23, University of Amsterdam24, Naturalis25, Federal University of Western Pará26, State University of Campinas27, National Institute for Space Research28, Florida International University29, University of São Paulo30, Tropenbos International31, Amazon.com32, Federal University of Pará33, Michigan Technological University34, University of Texas at Austin35, Polytechnic University of Valencia36, Venezuelan Institute for Scientific Research37, Royal Museum for Central Africa38, Tecnológico de Antioquia39, George Mason University40, Universidad del Tolima41, National University of Colombia42, Paul Sabatier University43, Georgetown University44, University of La Serena45, Forestry Commission46, Federal University of Alagoas47, Duke University48, Van Hall Larenstein University of Applied Sciences49, University of Nottingham50
TL;DR: A slow shift to a more dry‐affiliated Amazonia is underway, with changes in compositional dynamics consistent with climate‐change drivers, but yet to significantly impact whole‐community composition.
Abstract: Most of the planet's diversity is concentrated in the tropics, which includes many regions undergoing rapid climate change. Yet, while climate‐induced biodiversity changes are widely documented elsewhere, few studies have addressed this issue for lowland tropical ecosystems. Here we investigate whether the floristic and functional composition of intact lowland Amazonian forests have been changing by evaluating records from 106 long‐term inventory plots spanning 30 years. We analyse three traits that have been hypothesized to respond to different environmental drivers (increase in moisture stress and atmospheric CO2 concentrations): maximum tree size, biogeographic water‐deficit affiliation and wood density. Tree communities have become increasingly dominated by large‐statured taxa, but to date there has been no detectable change in mean wood density or water deficit affiliation at the community level, despite most forest plots having experienced an intensification of the dry season. However, among newly recruited trees, dry‐affiliated genera have become more abundant, while the mortality of wet‐affiliated genera has increased in those plots where the dry season has intensified most. Thus, a slow shift to a more dry‐affiliated Amazonia is underway, with changes in compositional dynamics (recruits and mortality) consistent with climate‐change drivers, but yet to significantly impact whole‐community composition. The Amazon observational record suggests that the increase in atmospheric CO2 is driving a shift within tree communities to large‐statured species and that climate changes to date will impact forest composition, but long generation times of tropical trees mean that biodiversity change is lagging behind climate change.
263 citations
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University of Bordeaux1, French Alternative Energies and Atomic Energy Commission2, Université Paris-Saclay3, Institut national de la recherche agronomique4, University of Lorraine5, University of Montpellier6, Science for Life Laboratory7, Helmholtz Centre for Environmental Research - UFZ8, University of Toulouse9, University of Strasbourg10, University of Perpignan11, University of Girona12, George Washington University13
TL;DR: Through this case study of oak, the accumulation and transmission of somatic mutations and the expansion of disease-resistance gene families in trees are demonstrated.
Abstract: Oaks are an important part of our natural and cultural heritage. Not only are they ubiquitous in our most common landscapes1 but they have also supplied human societies with invaluable services, including food and shelter, since prehistoric times2. With 450 species spread throughout Asia, Europe and America3, oaks constitute a critical global renewable resource. The longevity of oaks (several hundred years) probably underlies their emblematic cultural and historical importance. Such long-lived sessile organisms must persist in the face of a wide range of abiotic and biotic threats over their lifespans. We investigated the genomic features associated with such a long lifespan by sequencing, assembling and annotating the oak genome. We then used the growing number of whole-genome sequences for plants (including tree and herbaceous species) to investigate the parallel evolution of genomic characteristics potentially underpinning tree longevity. A further consequence of the long lifespan of trees is their accumulation of somatic mutations during mitotic divisions of stem cells present in the shoot apical meristems. Empirical4 and modelling5 approaches have shown that intra-organismal genetic heterogeneity can be selected for6 and provides direct fitness benefits in the arms race with short-lived pests and pathogens through a patchwork of intra-organismal phenotypes7. However, there is no clear proof that large-statured trees consist of a genetic mosaic of clonally distinct cell lineages within and between branches. Through this case study of oak, we demonstrate the accumulation and transmission of somatic mutations and the expansion of disease-resistance gene families in trees.
262 citations
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Peking University1, Chinese Academy of Sciences2, Spanish National Research Council3, University of California, Berkeley4, Carnegie Institution for Science5, Oak Ridge National Laboratory6, University of Lorraine7, Ghent University8, Northern Arizona University9, Boston University10, Sun Yat-sen University11, Brookhaven National Laboratory12, University of Hong Kong13, University of Antwerp14
TL;DR: In tropical forests in particular, Topteco is close to growing-season air temperature and is projected to fall below it under all scenarios of future climate, suggesting a limited safe operating space for these ecosystems under future warming.
Abstract: The global distribution of the optimum air temperature for ecosystem-level gross primary productivity ([Formula: see text]) is poorly understood, despite its importance for ecosystem carbon uptake under future warming. We provide empirical evidence for the existence of such an optimum, using measurements of in situ eddy covariance and satellite-derived proxies, and report its global distribution. [Formula: see text] is consistently lower than the physiological optimum temperature of leaf-level photosynthetic capacity, which typically exceeds 30 °C. The global average [Formula: see text] is estimated to be 23 ± 6 °C, with warmer regions having higher [Formula: see text] values than colder regions. In tropical forests in particular, [Formula: see text] is close to growing-season air temperature and is projected to fall below it under all scenarios of future climate, suggesting a limited safe operating space for these ecosystems under future warming.
261 citations
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University of Texas Southwestern Medical Center1, Kindai University2, University of California, San Francisco3, Fudan University4, University of Lorraine5, Huazhong University of Science and Technology6, Kyorin University7, Johns Hopkins University School of Medicine8, Nihon University9, Virginia Commonwealth University10, Catholic University of Korea11, Bayer HealthCare Pharmaceuticals12
TL;DR: The study showed that the safety profile of sorafenib was consistent across patients with preserved liver function and those in which the liver was not functioning properly, and therefore, suggesting that sorafinib may be a valid treatment for some patients with liver impairment.
260 citations
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TL;DR: In this review, the reasons for loss of activity during immobilization are outlined and suitable diagnostic tests are highlighted to elucidate the precise cause and thereby methods to restore activity.
260 citations
Authors
Showing all 12161 results
Name | H-index | Papers | Citations |
---|---|---|---|
Jonathan I. Epstein | 138 | 1121 | 80975 |
Peter Tugwell | 129 | 948 | 125480 |
David Brown | 105 | 1257 | 46827 |
Faiez Zannad | 103 | 839 | 90737 |
Sabu Thomas | 102 | 1554 | 51366 |
Francis Martin | 98 | 733 | 43991 |
João F. Mano | 97 | 822 | 36401 |
Jonathan A. Epstein | 94 | 299 | 27492 |
Muhammad Imran | 94 | 3053 | 51728 |
Laurent Peyrin-Biroulet | 90 | 901 | 34120 |
Athanase Benetos | 83 | 391 | 31718 |
Michel Marre | 82 | 444 | 39052 |
Bruno Rossion | 80 | 337 | 21902 |
Lyn March | 78 | 367 | 62536 |
Alan J. M. Baker | 76 | 234 | 26080 |