Institution
University of Los Andes
Education•Bogotá, Colombia•
About: University of Los Andes is a education organization based out in Bogotá, Colombia. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 17616 authors who have published 25555 publications receiving 413463 citations.
Papers published on a yearly basis
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TL;DR: It is proposed that the compartmentalisation of major parts of the enzyme repertoire involved in energy, carbohydrate and lipid metabolism has contributed to the multiple development of parasitism, and its elaboration to complicated life cycles involving consecutive different hosts, in the protists of the Kinetoplastea clade.
91 citations
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TL;DR: In this article, a search for narrow and broad resonances with masses greater than 1.8 TeV decaying to a pair of jets is presented, and the results show that no significant evidence for the production of new particles is observed.
Abstract: A search for narrow and broad resonances with masses greater than 1.8 TeV decaying to a pair of jets is presented. The search uses proton-proton collision data at $ \sqrt{s} $ = 13 TeV collected at the LHC, corresponding to an integrated luminosity of 137 fb$^{−1}$. The background arising from standard model processes is predicted with the fit method used in previous publications and with a new method. The dijet invariant mass spectrum is well described by both data-driven methods, and no significant evidence for the production of new particles is observed. Model independent upper limits are reported on the production cross sections of narrow resonances, and broad resonances with widths up to 55% of the resonance mass. Limits are presented on the masses of narrow resonances from various models: string resonances, scalar diquarks, axigluons, colorons, excited quarks, color-octet scalars, W′ and Z′ bosons, Randall-Sundrum gravitons, and dark matter mediators. The limits on narrow resonances are improved by 200 to 800 GeV relative to those reported in previous CMS dijet resonance searches. The limits on dark matter mediators are presented as a function of the resonance mass and width, and on the associated coupling strength as a function of the mediator mass. These limits exclude at 95% confidence level a dark matter mediator with a mass of 1.8 TeV and width 1% of its mass or higher, up to one with a mass of 4.8 TeV and a width 45% of its mass or higher.[graphic not available: see fulltext]
91 citations
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Joint Institute for Nuclear Research1, Tata Institute of Fundamental Research2, Petersburg Nuclear Physics Institute3, Fermilab4, Northeastern University5, Belarusian State University6, Northern Illinois University7, Moscow State University8, Boston University9, Florida State University10, University of Los Andes11, Universidad San Francisco de Quito12, University of Arizona13, Academy of Sciences of the Czech Republic14, Charles University in Prague15, University of Washington16, Indiana University17, Czech Technical University in Prague18, Brookhaven National Laboratory19
01 Nov 2005-Nuclear Instruments & Methods in Physics Research Section A-accelerators Spectrometers Detectors and Associated Equipment
TL;DR: In this paper, the design, construction, and performance of the upgraded DO-muon system for Run II of the Fermilab Tevatron collider is described, and extensive shielding has been added in the forward region.
Abstract: We describe the design, construction, and performance of the upgraded DO muon system for Run II of the Fermilab Tevatron collider. Significant improvements have been made to the major subsystems of the DO muon detector: trigger scintillation counters, tracking detectors, and electronics. The Run II central muon detector has a new scintillation counter system inside the iron toroid and an improved scintillation counter system outside the iron toroid. In the forward region, new scintillation counter and tracking systems have been installed. Extensive shielding has been added in the forward region. A large fraction of the muon system electronics is also new.
91 citations
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TL;DR: In vivo studies indicated that E5700 was able to provide full protection against death and completely arrested the development of parasitemia when given at a concentration of 50 mg/kg of body weight/day for 30 days, while ER-119884 provided only partial protection.
Abstract: Chagas' disease is a serious public health problem in Latin America, and no treatment is available for the prevalent chronic stage. Its causative agent, Trypanosoma cruzi, requires specific endogenous sterols for survival, and we have recently demonstrated that squalene synthase (SQS) is a promising target for antiparasitic chemotherapy. E5700 and ER-119884 are quinuclidine-based inhibitors of mammalian SQS that are currently in development as cholesterol- and triglyceride-lowering agents in humans. These compounds were found to be potent noncompetitive or mixed-type inhibitors of T. cruzi SQS with K(i) values in the low nanomolar to subnanomolar range in the absence or presence of 20 microM inorganic pyrophosphate. The antiproliferative 50% inhibitory concentrations of the compounds against extracellular epimastigotes and intracellular amastigotes were ca. 10 nM and 0.4 to 1.6 nM, respectively, with no effects on host cells. When treated with these compounds at the MIC, all of the parasite's sterols disappeared from the parasite cells. In vivo studies indicated that E5700 was able to provide full protection against death and completely arrested the development of parasitemia when given at a concentration of 50 mg/kg of body weight/day for 30 days, while ER-119884 provided only partial protection. This is the first report of an orally active SQS inhibitor that is capable of providing complete protection against fulminant, acute Chagas' disease.
91 citations
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TL;DR: Different types of fields are considered, interpreted as forms of mass media acting on a social system in the context of Axelrod's model for cultural dissemination, which is a nonequilibrium system of locally interacting elements in a lattice with an absorbing order-disorder phase transition.
Abstract: A nonequilibrium system of locally interacting elements in a lattice with an absorbing order-disorder phase transition is studied under the effect of additional interacting fields. These fields are shown to produce interesting effects in the collective behavior of this system. Both for autonomous and external fields, disorder grows in the system when the probability of the elements to interact with the field is increased. There exists a threshold value of this probability beyond which the system is always disordered. The domain of parameters of the ordered regime is larger for nonuniform local fields than for spatially uniform fields. However, the zero field limit is discontinous. In the limit of vanishingly small probability of interaction with the field, autonomous or external fields are able to order a system that would fall in a disordered phase under local interactions of the elements alone. We consider different types of fields which are interpreted as forms of mass media acting on a social system in the context of Axelrod's model for cultural dissemination.
91 citations
Authors
Showing all 17748 results
Name | H-index | Papers | Citations |
---|---|---|---|
Alexander Belyaev | 142 | 1895 | 100796 |
Sarah Catherine Eno | 141 | 1645 | 105935 |
Mitchell Wayne | 139 | 1810 | 108776 |
Kaushik De | 139 | 1625 | 102058 |
Pierluigi Paolucci | 138 | 1965 | 105050 |
Randy Ruchti | 137 | 1832 | 107846 |
Gabor Istvan Veres | 135 | 1349 | 96104 |
Raymond Brock | 135 | 1468 | 97859 |
Harrison Prosper | 134 | 1587 | 100607 |
J. Ellison | 133 | 1392 | 92416 |
Gyorgy Vesztergombi | 133 | 1444 | 94821 |
Andrew Brandt | 132 | 1246 | 94676 |
Scott Snyder | 131 | 1317 | 93376 |
Shuai Liu | 129 | 1095 | 80823 |
C. A. Carrillo Montoya | 128 | 1033 | 78628 |