Institution
University of Louisville
Education•Louisville, Kentucky, United States•
About: University of Louisville is a education organization based out in Louisville, Kentucky, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 24600 authors who have published 49248 publications receiving 1573346 citations. The organization is also known as: UofL.
Topics: Population, Poison control, Transplantation, Stem cell, Breast cancer
Papers published on a yearly basis
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University of Nebraska Medical Center1, Uppsala University2, Gentofte Hospital3, Lund University4, Oulu University Hospital5, Umeå University6, Uppsala University Hospital7, Aberdeen Royal Infirmary8, University of Cambridge9, Manchester Royal Eye Hospital10, Moorfields Eye Hospital11, Ninewells Hospital12, University of Nottingham13, Alexandra Hospital14, Royal Free Hospital15, Royal Hallamshire Hospital16, Royal Liverpool University Hospital17, University Hospital of Wales18, Medical University of South Carolina19, Mount Sinai Hospital20, New York Eye and Ear Infirmary21, Northwestern University22, University of California, San Diego23, University of Florida24, University of Illinois at Chicago25, University of Louisville26, University of Michigan27, University of Southern California28, University of Wisconsin-Madison29, Washington University in St. Louis30, Wills Eye Institute31, Johns Hopkins University32
TL;DR: In this article, Latanoprost was applied once daily for 12 months in patients from Scandinavia, the United Kingdom, and the United States who had elevated intraocular pressure (IOP).
231 citations
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TL;DR: Among patients with COPD, long-term exposure to fluticasone and budesonide is consistently associated with a modest but statistically significant increased likelihood of fractures.
Abstract: Background The effect of inhaled corticosteroids (ICS) on fracture risk in patients with chronic obstructive pulmonary disease (COPD) remains uncertain. The aim of this study was to evaluate the association between ICS and fractures in COPD. Methods MEDLINE, EMBASE, regulatory documents and company registries were searched up to August 2010. Randomised controlled trials (RCTs) of budesonide or fluticasone versus control treatment for COPD (≥24 weeks duration) and controlled observational studies reporting on fracture risk with ICS exposure vs no exposure in COPD were included. Peto OR meta-analysis was used for fracture risk from RCTs while ORs from observational studies were pooled using the fixed effect inverse variance method. Dose–response analysis was conducted using variance-weighted least squares regression in the observational studies. Heterogeneity was assessed using the I 2 statistic. Results Sixteen RCTs (14 fluticasone, 2 budesonide) with 17 513 participants, and seven observational studies (n=69 000 participants) were included in the meta-analysis. ICSs were associated with a significantly increased risk of fractures (Peto OR 1.27; 95% CI 1.01 to 1.58; p=0.04; I 2 =0%) in the RCTs. In the observational studies, ICS exposure was associated with a significantly increased risk of fractures (OR 1.21; 95% CI 1.12 to 1.32; p 2 =37%), with each 500 μg increase in beclomethasone dose equivalents associated with a 9% increased risk of fractures, OR 1.09 (95% CI 1.06 to 1.12; p Conclusion Among patients with COPD, long-term exposure to fluticasone and budesonide is consistently associated with a modest but statistically significant increased likelihood of fractures.
231 citations
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TL;DR: This prospective, multicenter study demonstrates that infection frequently complicates VAD placement and is a continuing problem despite the use of newer, smaller devices.
Abstract: Background—Ventricular assist devices (VADs) improve survival and quality of life in patients with advanced heart failure, but their use is frequently complicated by infection. There are limited data on the microbiology and epidemiology of these infections. Methods and Results—One hundred fifty patients scheduled for VAD implantation were enrolled (2006–2008) at 11 US cardiac centers and followed prospectively until transplantation, explantation for recovery, death, or for 1 year. Eighty-six patients (57%) received HeartMate II devices. Data were collected on potential preoperative, intraoperative, and postoperative risk factors for infection. Clinical, laboratory, and microbiological data were collected for suspected infections and evaluated by an infectious diseases specialist. Thirty-three patients (22%) developed 34 VAD-related infections with an incidence rate of 0.10 per 100 person-days (95% confidence interval, 0.073–0.142). The median time to infection was 68 days. The driveline was the most commo...
231 citations
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TL;DR: The mobilization of nonhematopoietic very small embryonic-like stem cells (VSELs) in acute myocardial infarction was significantly reduced in patients older than 50 years and with diabetes in comparison with younger and nondiabetic patients.
230 citations
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TL;DR: A method to store each element of an integral memory set M subset M subset as a fixed point into a complex-valued multistate Hopfield network is introduced and the performance of the proposed method in reconstructing noisy gray-scale images is enlightened.
Abstract: A method to store each element of an integral memory set M /spl sub/ {1,2,...,K}/sup n/ as a fixed point into a complex-valued multistate Hopfield network is introduced. The method employs a set of inequalities to render each memory pattern as a strict local minimum of a quadratic energy landscape. Based on the solution of this system, it gives a recurrent network of n multistate neurons with complex and symmetric synaptic weights, which operates on the finite state space {1,2,...,K}/sup n/ to minimize this quadratic functional. Maximum number of integral vectors that can be embedded into the energy landscape of the network by this method is investigated by computer experiments. This paper also enlightens the performance of the proposed method in reconstructing noisy gray-scale images.
230 citations
Authors
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Name | H-index | Papers | Citations |
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Robert M. Califf | 196 | 1561 | 167961 |
Aaron R. Folsom | 181 | 1118 | 134044 |
Yang Gao | 168 | 2047 | 146301 |
Stephen J. O'Brien | 153 | 1062 | 93025 |
James J. Collins | 151 | 669 | 89476 |
Anthony E. Lang | 149 | 1028 | 95630 |
Sw. Banerjee | 146 | 1906 | 124364 |
Hermann Kolanoski | 145 | 1279 | 96152 |
Ferenc A. Jolesz | 143 | 631 | 66198 |
Daniel S. Berman | 141 | 1363 | 86136 |
Aaron T. Beck | 139 | 536 | 170816 |
Kevin J. Tracey | 138 | 561 | 82791 |
C. Dallapiccola | 136 | 1717 | 101947 |
Michael I. Posner | 134 | 414 | 104201 |
Alan Sher | 132 | 486 | 68128 |