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Institution

University of Louisville

EducationLouisville, Kentucky, United States
About: University of Louisville is a education organization based out in Louisville, Kentucky, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 24600 authors who have published 49248 publications receiving 1573346 citations. The organization is also known as: UofL.


Papers
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Journal ArticleDOI
TL;DR: In this paper, the authors suggest that at least part of the long-term toxicity may involve iron-mediated oxidative damage to the mitochondrial genome with an accumulation of mutational events leading to progressive mitochondrial dysfunction.

353 citations

Journal ArticleDOI
TL;DR: A Williams Syndrome Cognitive Profile (WSCP) is outlined that operationalizes the cognitive characteristics of the syndrome using measures of absolute and relative performance on subtests of the Differential Abilities Scales (Elliot, 1990a).

353 citations

Journal ArticleDOI
TL;DR: Using a proteomics approach, enolase, glyceraldehyde-3-phosphate dehydrogenase, ATP synthase alpha chain, carbonic anhydrase-II, and voltage-dependent anion channel-protein are identified as the targets of nitration in AD hippocampus, a region that shows a extensive deposition of amyloid beta-peptide compared with the age-matched control brains.

353 citations

Journal ArticleDOI
TL;DR: Five scales were assessed as mental health measures for older persons: Affect Balance, The Center for Epidemiological Studies Depression Scale, General Well-Being, LSI-Z Life Satisfaction, and Trait-Anxiety Inventory, finding that all scales significantly discriminated between the two samples.
Abstract: Five scales were assessed as mental health measures for older persons: Affect Balance, The Center for Epidemiological Studies Depression Scale, General Well-Being, LSI-Z Life Satisfaction, and Trait-Anxiety Inventory. These scales were administered to a community sample of 279 older persons and a clinical sample of 109 older persons who were in psychiatric inpatient units. In both samples, the internal consistency reliabilities for the anxiety, depression, and well-being scales were moderately high to high, for the life satisfaction scale they were acceptable, but the reliabilities for the affect balance scale suggest some caution in its use. For validity, multivariate analyses of variance found that all scales significantly discriminated between the two samples. The well-being and then depression scales were the strongest discriminators while the life satisfaction scale had the weakest validity. Cutting points for the well-being and depression scales are suggested for estimating the proportions of older persons who would be probable at-risk for disorder that requires intervention.

353 citations

Journal ArticleDOI
TL;DR: It is demonstrated for the first time that lipid accumulation in hepatocytes can stimulate IL‐8 production, thereby potentially contributing to hepatic inflammation and consequent liver injury.

352 citations


Authors

Showing all 24802 results

NameH-indexPapersCitations
Robert M. Califf1961561167961
Aaron R. Folsom1811118134044
Yang Gao1682047146301
Stephen J. O'Brien153106293025
James J. Collins15166989476
Anthony E. Lang149102895630
Sw. Banerjee1461906124364
Hermann Kolanoski145127996152
Ferenc A. Jolesz14363166198
Daniel S. Berman141136386136
Aaron T. Beck139536170816
Kevin J. Tracey13856182791
C. Dallapiccola1361717101947
Michael I. Posner134414104201
Alan Sher13248668128
Network Information
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202373
2022249
20212,489
20202,234
20192,193
20182,153