University of Luxembourg

About: University of Luxembourg is a education organization based out in Luxembourg, Luxembourg. It is known for research contribution in the topics: Context (language use) & Computer science. The organization has 4744 authors who have published 22175 publications receiving 381824 citations.

International entrepreneurship and the small business

Abstract: The topic of ‘international entrepreneurship’ is becoming increasingly popular with researchers concerned with examining how international and entrepreneurial activities intersect when people in organizations engage in pro-active brokering and risk-taking behaviour in cross-border contexts. Some caution is needed in over-generalizing the meaning and significance of international entrepreneurship – especially in relation to small businesses. Not all entrepreneurial risk-taking, brokering and opportunity-seeking activities lead to internationalization (as the statistics on small business international activities indicate). This might suggest then that the only truly internationally entrepreneurial firms are those that are ‘born global’. However, their entrepreneurial activities are more ‘spatial’, concerned with what can be constructed again in relation to global markets rather than in relation to the local/regional context in which the business is located. For small firms that internationalize a few years ...

A Tutorial on Interference Exploitation via Symbol-Level Precoding: Overview, State-of-the-Art and Future Directions

Abstract: Interference is traditionally viewed as a performance limiting factor in wireless communication systems, which is to be minimized or mitigated. Nevertheless, a recent line of work has shown that by manipulating the interfering signals such that they add up constructively at the receiver side, known interference can be made beneficial and further improve the system performance in a variety of wireless scenarios, achieved by symbol-level precoding (SLP). This paper aims to provide a tutorial on interference exploitation techniques from the perspective of precoding design in a multi-antenna wireless communication system, by beginning with the classification of constructive interference (CI) and destructive interference (DI). The definition for CI is presented and the corresponding mathematical characterization is formulated for popular modulation types, based on which optimization-based precoding techniques are discussed. In addition, the extension of CI precoding to other application scenarios as well as for hardware efficiency is also described. Proof-of-concept testbeds are demonstrated for the potential practical implementation of CI precoding, and finally a list of open problems and practical challenges are presented to inspire and motivate further research directions in this area.

Harbor seal vibrissa morphology suppresses vortex-induced vibrations.

Abstract: SUMMARY Harbor seals ( Phoca vitulina ) often live in dark and turbid waters, where their mystacial vibrissae, or whiskers, play an important role in orientation. Besides detecting and discriminating objects by direct touch, harbor seals use their whiskers to analyze water movements, for example those generated by prey fish or by conspecifics. Even the weak water movements left behind by objects that have passed by earlier can be sensed and followed accurately (hydrodynamic trail following). While scanning the water for these hydrodynamic signals at a swimming speed in the order of meters per second, the seal keeps its long and flexible whiskers in an abducted position, largely perpendicular to the swimming direction. Remarkably, the whiskers of harbor seals possess a specialized undulated surface structure, the function of which was, up to now, unknown. Here, we show that this structure effectively changes the vortex street behind the whiskers and reduces the vibrations that would otherwise be induced by the shedding of vortices from the whiskers (vortex-induced vibrations). Using force measurements, flow measurements and numerical simulations, we find that the dynamic forces on harbor seal whiskers are, by at least an order of magnitude, lower than those on sea lion ( Zalophus californianus ) whiskers, which do not share the undulated structure. The results are discussed in the light of pinniped sensory biology and potential biomimetic applications.

Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes.

Abstract: Febrile seizures affect 2-4% of all children and have a strong genetic component. Recurrent mutations in three main genes (SCN1A, SCN1B and GABRG2) have been identified that cause febrile seizures with or without epilepsy. Here we report the identification of mutations in STX1B, encoding syntaxin-1B, that are associated with both febrile seizures and epilepsy. Whole-exome sequencing in independent large pedigrees identified cosegregating STX1B mutations predicted to cause an early truncation or an in-frame insertion or deletion. Three additional nonsense or missense mutations and a de novo microdeletion encompassing STX1B were then identified in 449 familial or sporadic cases. Video and local field potential analyses of zebrafish larvae with antisense knockdown of stx1b showed seizure-like behavior and epileptiform discharges that were highly sensitive to increased temperature. Wild-type human syntaxin-1B but not a mutated protein rescued the effects of stx1b knockdown in zebrafish. Our results thus implicate STX1B and the presynaptic release machinery in fever-associated epilepsy syndromes.