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Institution

University of Madras

EducationChennai, Tamil Nadu, India
About: University of Madras is a education organization based out in Chennai, Tamil Nadu, India. It is known for research contribution in the topics: Ring (chemistry) & Lipid peroxidation. The organization has 8496 authors who have published 11369 publications receiving 211152 citations. The organization is also known as: Madras University & University of Chennai.


Papers
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Journal ArticleDOI
TL;DR: A novel vanadium-flavonol complex was synthesized, characterized and its toxic as well as insulin mimetic potential was evaluated in STZ-induced experimental diabetes in rats, and results indicate that the complex is non-toxic and possess anti-diabetic activity.

67 citations

Journal ArticleDOI
TL;DR: Both in chronic and acute inflammation, ethyl acetate (EAF) and aqueous fraction (AF) were effective and EAF is comparable with the positive standards in chronic inflammation.

67 citations

Journal ArticleDOI
TL;DR: High level aminoglycoside resistance genes are widely disseminated among isolates of enterococci from Chennai.
Abstract: Enterococci are nosocomial pathogen with multiple-drug resistance by intrinsic and extrinsic mechanisms. Aminoglycosides along with cell wall inhibitors are given clinically for treating enterococcal infections. 178 enterococcal isolates were analyzed in this study. E. faecalis is identified to be the predominant Enterococcus species, along with E. faecium, E. avium, E. hirae, E. durans, E. dispar and E. gallinarum. High level aminoglycoside resistance (HLAR) by MIC for gentamicin (GM), streptomycin (SM) and both (GM + SM) antibiotics was found to be 42.7%, 29.8%, and 21.9%, respectively. Detection of aminoglycoside modifying enzyme encoding genes (AME) in enterococci was identified by multiplex PCR for aac(6')-Ie-aph(2'')-Ia; aph(2'')-Ib; aph(2'')-Ic; aph(2'')-Id and aph(3')-IIIa genes. 38.2% isolates carried aac(6')-Ie-aph(2'')-Ia gene and 40.4% isolates carried aph(3')-IIIa gene. aph(2'')-Ib; aph(2'')-Ic; aph(2'')-Id were not detected among our study isolates. aac(6')-Ie-aph(2'')-Ia and aph(3')-IIIa genes were also observed in HLAR E. durans, E. avium, E. hirae, and E. gallinarum isolates. This indicates that high level aminoglycoside resistance genes are widely disseminated among isolates of enterococci from Chennai.

67 citations

Journal ArticleDOI
TL;DR: It is suggested that thymoquinone has a potent anti proliferative activity by regulating the G1/S phase cell cycle transition and exhibit a beneficial role in the treatment of HCC.

67 citations

Journal ArticleDOI
TL;DR: In this paper, the seasonal variation of redox potential (Eh) and redox species such as As(V)/As(III), Cr(VI)/Cr(III, Fe(III)/Fe(II), NO 3 - / NO 2 -, and Se(VI/Se(IV) were studied in a shallow groundwater for a period of three years (May, 2004-January, 2007).

67 citations


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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202315
202283
2021644
2020564
2019457
2018435