Institution
University of Madras
Education•Chennai, Tamil Nadu, India•
About: University of Madras is a education organization based out in Chennai, Tamil Nadu, India. It is known for research contribution in the topics: Ring (chemistry) & Lipid peroxidation. The organization has 8496 authors who have published 11369 publications receiving 211152 citations. The organization is also known as: Madras University & University of Chennai.
Papers published on a yearly basis
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TL;DR: Gel titania is the titania which was prepared by hydrolysis of a titanium isopropoxide through a sol-gel process and a film of this titania was coated on surgical grade 316L stainless steel using a sol−gel dipping technique as discussed by the authors.
62 citations
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TL;DR: The presence of oxidative stress in selenite cataract development and its prevention byCurcumin support the possibility that the natural consumption of curcumin in food can help prevent the onset of senile cataracts.
Abstract: Purpose: The present study was aimed at investigating the possible antioxidant potential of curcumin at a dose of 75 mg/kg body weight on selenite-induced cataract in experimental rat pups.Methods: Group I: Control rat pups receiving physiological saline; Group II: Selenite-induced group (15 µM/kg body wt); Group III: Selenite-induced group co-treated with curcumin (single dose of curcumin orally 75 mg/kg body wt); Group IV: Selenite-induced animals post-treated (after 24 hrs) with curcumin at a dose mentioned for group III; Group V: Rat pups were pretreated with curcumin (dose as mentioned in Group III), 24 hrs before the administration of selenite. Encapsulated lenses liver, kidney, and serum were analyzed for antioxidant enzymes and malondialdehyde, a marker of lipid peroxidation.Results: Intraperitoneal injection of sodium selenite (15 µM/kg body wt) to 8–10-day-old rat pups led to severe oxidative stress in eye lens as evidenced by enhanced LPO levels that led to cataract formation. Sodium selenite a...
62 citations
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TL;DR: This is the first report of PGPMCs mediated biological control of SNVD under field conditions and significantly reduced SNVD up to 51.4% compared to control.
62 citations
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TL;DR: Results suggested that phytosynthesized AuNPs of C. roxburghii extract clearly limited toxic on normal cells but toxic in cancer cells.
Abstract: Gold nanoparticles are considered of great importance compared to other noble metal nanoparticles and its wide range of applications like pharmaceutics, therapeutics and diagnostics etc. During the past decade, phytosynthesized gold nanoparticles (AuNPs) are more focused in in vitro and in vivo study. The present study was focused on the gold chloride and phytosynthesized gold nanoparticles from aqueous leaf extract of Cassia roxburghii and their toxic effects on African green monkey normal kidney Vero cell line and three different cancer cell lines such as HepG2, MCF7 and HeLa. Phytosynthesized AuNPs were characterized by HRTEM, EDX, XRD and FTIR analysis. The particles size range of 25-35nm was confirmed by HRTEM. The elemental gold and the crystalline nature of AuNPs were confirmed by EDX and XRD, respectively. The reduction of functional groups was confirmed by FTIR. In in vitro study, the IC50 of HepG2 cells was found to be 30μg/ml compared to other cell lines, HeLa and MCF7 cell line showing IC50 of 50μg/ml and normal Vero cell line also nontoxic up to 75μg/ml confirmed by MTT assay. Further, apoptosis in HepG2 was analyzed by fluorescence microscope and DNA fragmentation was observed in HepG2 treated cells. These results suggested that phytosynthesized AuNPs of C. roxburghii extract clearly limited toxic on normal cells but toxic in cancer cells.
62 citations
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TL;DR: In this article, the absorption edge of doped TiO2 is at a higher wavelength that corresponds to red region, because of the formation of intermediate states in the doped metal ions into TiO 2 sites.
62 citations
Authors
Showing all 8535 results
Name | H-index | Papers | Citations |
---|---|---|---|
David A. Kass | 127 | 580 | 58747 |
Viswanathan Mohan | 110 | 964 | 64896 |
Sridevi Devaraj | 85 | 365 | 21831 |
Raghavan Srinivasan | 80 | 959 | 37821 |
Muthupandian Ashokkumar | 76 | 511 | 20771 |
K.V. Rajagopalan | 71 | 223 | 15129 |
Rajasekhar Balasubramanian | 65 | 276 | 13854 |
Savarimuthu Ignacimuthu | 64 | 498 | 17752 |
Pappannan Thiyagarajan | 59 | 245 | 10650 |
Ravi Subrahmanyan | 59 | 353 | 14244 |
Fritz Scholz | 55 | 385 | 11420 |
M. Lakshmanan | 54 | 533 | 13357 |
Nagarajan Selvamurugan | 52 | 153 | 9477 |
Kumarasamy Thangaraj | 47 | 361 | 11869 |
Suniti Solomon | 46 | 191 | 6400 |