Institution
University of Madras
Education•Chennai, Tamil Nadu, India•
About: University of Madras is a education organization based out in Chennai, Tamil Nadu, India. It is known for research contribution in the topics: Ring (chemistry) & Lipid peroxidation. The organization has 8496 authors who have published 11369 publications receiving 211152 citations. The organization is also known as: Madras University & University of Chennai.
Papers published on a yearly basis
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TL;DR: EGCG has emerged out as a good antioxidant neutraceutical and a neuroprotective agent in alleviating the age‐associated oxidative damage in aged rat brain.
114 citations
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University of Washington1, Emory University2, Johns Hopkins University3, University of North Carolina at Chapel Hill4, University of Connecticut5, Harvard University6, University of British Columbia7, Loyola University Chicago8, University of California, San Francisco9, Oswaldo Cruz Foundation10, University of Madras11, University of California, Los Angeles12, University of Bordeaux13, University of California, San Diego14
TL;DR: Data support the integration of biomedical and behavioral approaches for prevention of HIV infection in clinical care settings and a concerted effort to implement combination strategies for HIV prevention is needed to realize the goal of an AIDS-free generation.
Abstract: Importance Emerging data warrant the integration of biomedical and behavioral recommendations for human immunodeficiency virus (HIV) prevention in clinical care settings. Objective To provide current recommendations for the prevention of HIV infection in adults and adolescents for integration in clinical care settings. Data Sources, Study Selection, and Data Synthesis Data published or presented as abstracts at scientific conferences (past 17 years) were systematically searched and reviewed by the International Antiviral (formerly AIDS) Society—USA HIV Prevention Recommendations Panel. Panel members supplied additional relevant publications, reviewed available data, and formed recommendations by full-panel consensus. Results Testing for HIV is recommended at least once for all adults and adolescents, with repeated testing for those at increased risk of acquiring HIV. Clinicians should be alert to the possibility of acute HIV infection and promptly pursue diagnostic testing if suspected. At diagnosis of HIV, all individuals should be linked to care for timely initiation of antiretroviral therapy (ART). Support for adherence and retention in care, individualized risk assessment and counseling, assistance with partner notification, and periodic screening for common sexually transmitted infections (STIs) is recommended for HIV-infected individuals as part of care. In HIV-uninfected patients, those persons at high risk of HIV infection should be prioritized for delivery of interventions such as preexposure prophylaxis and individualized counseling on risk reduction. Daily emtricitabine/tenofovir disoproxil fumarate is recommended as preexposure prophylaxis for persons at high risk for HIV based on background incidence or recent diagnosis of incident STIs, use of injection drugs or shared needles, or recent use of nonoccupational postexposure prophylaxis; ongoing use of preexposure prophylaxis should be guided by regular risk assessment. For persons who inject drugs, harm reduction services should be provided (needle and syringe exchange programs, supervised injection, and available medically assisted therapies, including opioid agonists and antagonists); low-threshold detoxification and drug cessation programs should be made available. Postexposure prophylaxis is recommended for all persons who have sustained a mucosal or parenteral exposure to HIV from a known infected source and should be initiated as soon as possible. Conclusions and Relevance Data support the integration of biomedical and behavioral approaches for prevention of HIV infection in clinical care settings. A concerted effort to implement combination strategies for HIV prevention is needed to realize the goal of an AIDS-free generation.
113 citations
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TL;DR: It could be concluded that Cassia fistula bark extracts (CFA & CFM) possess significant anti-inflammatory and anti oxidant properties.
Abstract: Anti-inflammatory and Antioxidant activities of the aqueous (CFA) and methanolic extracts (CFM) of the Cassia fistula Linn. bark were assayed in wistar albino rats. The extracts were found to posses significant anti-inflammatory effect in both acute and chronic models. Cassia fistula bark extracts showed significant radical scavenging by inhibiting lipid peroxidation initiated by CCl4 and FeSO4 in rat liver and kidney homogenates. Both extracts exhibited significant antioxidant activity in DPPH, Nitric oxide and Hydroxyl radical induced invitro assay methods. Both extracts showed Dose-dependent protective effect against lipid peroxidation and free radical generation in liver and kidney homogenates. Further, the acute toxicity study with the extracts showed no sign of toxicity up to a dose level of 2000 mg/ po. Thus it could be concluded that Cassia fistula bark extracts (CFA & CFM) possess significant anti-inflammatory and anti oxidant properties.
113 citations
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TL;DR: The present findings collectively suggest that AGN exerts its neuroprotection in ROT model of PD and may act as an effective agent for treatment of PD.
113 citations
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TL;DR: It is concluded that the extract contains as yet unidentified anti-inflammatory principle(s) and contains alkaloids, saponins, steroids and flavonoids.
Abstract: 1. The anti-inflammatory effect of an alcoholic extract from the flower of Vernonia cinerea (Asteraceae; Less) was tested in adjuvant arthritic rats. 2. Changes in paw volume, body and tissue weights and serum and tissue enzyme activities of ALT, AST, ACP and cathepsin-D in adjuvant rats were reversed by oral administration of 100 mg/kg body weight (BW) of the flower extract. 3. The extract also reversed the major histopathological changes in the hindpaws of the arthritic rats. 4. Phytochemical studies revealed the presence of alkaloids, saponins, steroids and flavonoids. 5. It is concluded that the extract contains as yet unidentified anti-inflammatory principle(s).
113 citations
Authors
Showing all 8535 results
Name | H-index | Papers | Citations |
---|---|---|---|
David A. Kass | 127 | 580 | 58747 |
Viswanathan Mohan | 110 | 964 | 64896 |
Sridevi Devaraj | 85 | 365 | 21831 |
Raghavan Srinivasan | 80 | 959 | 37821 |
Muthupandian Ashokkumar | 76 | 511 | 20771 |
K.V. Rajagopalan | 71 | 223 | 15129 |
Rajasekhar Balasubramanian | 65 | 276 | 13854 |
Savarimuthu Ignacimuthu | 64 | 498 | 17752 |
Pappannan Thiyagarajan | 59 | 245 | 10650 |
Ravi Subrahmanyan | 59 | 353 | 14244 |
Fritz Scholz | 55 | 385 | 11420 |
M. Lakshmanan | 54 | 533 | 13357 |
Nagarajan Selvamurugan | 52 | 153 | 9477 |
Kumarasamy Thangaraj | 47 | 361 | 11869 |
Suniti Solomon | 46 | 191 | 6400 |