scispace - formally typeset
Search or ask a question
Institution

University of Malaya

EducationKuala Lumpur, Malaysia
About: University of Malaya is a education organization based out in Kuala Lumpur, Malaysia. It is known for research contribution in the topics: Population & Fiber laser. The organization has 25087 authors who have published 51491 publications receiving 1036791 citations. The organization is also known as: UM & Universiti Malaya.


Papers
More filters
Journal ArticleDOI
TL;DR: The consequences of the evolutionary dynamics of EV-71 for vaccine design and compare its phylodynamic behavior with that of influenza virus are discussed and its phylogenetic and population genetic methods are analyzed.
Abstract: Human enterovirus 71 (EV-71) is one of the major etiologic causes of hand, foot, and mouth disease (HFMD) among young children worldwide, with fatal instances of neurological complications becoming increasingly common. Global VP1 capsid sequences (n 628) sampled over 4 decades were collected and subjected to comprehensive evolutionary analysis using a suite of phylogenetic and population genetic methods. We estimated that the common ancestor of human EV-71 likely emerged around 1941 (95% confidence interval [CI], 1929 to 1952), subsequently diverging into three genogroups: B, C, and the now extinct genogroup A. Genealogical analysis revealed that diverse lineages of genogroup B and C (subgenogroups B1 to B5 and C1 to C5) have each circulated cryptically in the human population for up to 5 years before causing large HFMD outbreaks, indicating the quiescent persistence of EV-71 in human populations. Estimated phylogenies showed a complex pattern of spatial structure within well-sampled subgenogroups, suggesting endemicity with occasional lineage migration among locations, such that past HFMD epidemics are unlikely to be linked to continuous transmission of a single strain of virus. In addition, rises in genetic diversity are correlated with the onset of epidemics, driven in part by the emergence of novel EV-71 subgenogroups. Using subgenogroup C1 as a model, we observe temporal strain replacement through time, and we investigate the evidence for positive selection at VP1 immunogenic sites. We discuss the consequences of the evolutionary dynamics of EV-71 for vaccine design and compare its phylodynamic behavior with that of influenza virus.

220 citations

Journal ArticleDOI
TL;DR: In this article, the analysis of the thermochemical conversion of biomass with the use of thermogravimetric analyzer and Fourier transform infrared spectroscopic (FTIR) analyzer is discussed.

220 citations

Journal ArticleDOI
TL;DR: In this paper, a comprehensive review on different CFD approaches employed in numerical simulation of nanofluid flow, address the pros and cons of each approach, and find the suitable technique which gives more credible results as compared to experimental results.
Abstract: The recent development of nanotechnology led to the concept of using suspended nanoparticles in heat transfer fluids to improve the heat transfer coefficient of the base fluids. Specifically, numerical studies are reviewed in this study to get a clear view and detailed summary of the influence of several parameters such as type of nanoparticle and host liquid, particle volume concentration, particle size, particle shape, Brownian diffusion and thermophoresis effect on hydrodynamic and thermal characteristics of convective heat transfer using nanofluids. In addition, the paper provides detailed information about the most of commonly-used correlations which are utilized to predict the effective thermophysical properties of nanofluids. Finally, the main aim upon which the present work is based is to give a comprehensive review on different CFD approaches employed in numerical simulation of nanofluid flow, address the pros and cons of each approach, and find the suitable technique which gives more credible results as compared to experimental results.

219 citations

Journal ArticleDOI
TL;DR: In this article, the causal relationship among energy consumption, economic growth, relative price, financial development (FD) and foreign direct investment in Malaysia using a multivariate framework was analyzed. But the authors did not consider the impact of energy consumption and economic growth Granger causes each other.
Abstract: The aim of this study is to analyse the causal relationship among energy consumption, economic growth, relative price, financial development (FD) and foreign direct investment in Malaysia using a multivariate framework. This study covers a sample from 1972 to 2009. Both the Johansen–Juselius cointegration test and bounds testing approach to cointegration consistently suggest that the variables are cointegrated. We find that energy consumption and economic growth Granger causes each other in the short and long run. In addition, both FDI-led growth and finance-led growth hypotheses are also supported by the findings from this study. Ultimately, energy is a prominent resource for financial sector development in Malaysia because we find that energy consumption Granger causes FD. Policymakers should implement a dual strategy that, on one hand, increases investment in energy infrastructure to ensure that the supply of energy is sufficient for the financial sector and economic development, while, on the other, encourages R&D in green technology such as exercising proper soil conservation techniques and sustainable farming practices in order to reduce the consumption of fossil fuels. By doing so, environmental problems such as carbon dioxide emissions can be minimised without affecting economic growth and financial sector development in Malaysia.

219 citations

Journal ArticleDOI
TL;DR: In this paper, the authors assessed the worldwide biofuel scenario by biofuel policies and standards and summarized different biofuel processing techniques, and prescribed guidelines on dedicated biofuel engine for commercializing biodiesel.

219 citations


Authors

Showing all 25327 results

NameH-indexPapersCitations
Diederick E. Grobbee1551051122748
Intae Yu134137289870
Ovsat Abdinov12986478489
Jyothsna Rani Komaragiri129109782258
Odette Benary12884474238
Paul M. Vanhoutte12786862177
Irene Vichou12676272520
Ian O. Ellis126105175435
Louisa Degenhardt126798139683
Matthew Jones125116196909
Andrius Juodagalvis118106967138
Martin Ravallion11557055380
R. St. Denis11292165326
Xiao-Ming Chen10859642229
A. Yurkewicz10651451537
Network Information
Related Institutions (5)
National University of Singapore
165.4K papers, 5.4M citations

91% related

University of Hong Kong
99.1K papers, 3.2M citations

91% related

Shandong University
99.1K papers, 1.6M citations

89% related

Zhejiang University
183.2K papers, 3.4M citations

89% related

RMIT University
82.9K papers, 1.7M citations

89% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202391
2022418
20213,698
20203,646
20193,239
20183,203