Institution
University of Malaya
Education•Kuala Lumpur, Malaysia•
About: University of Malaya is a education organization based out in Kuala Lumpur, Malaysia. It is known for research contribution in the topics: Population & Fiber laser. The organization has 25087 authors who have published 51491 publications receiving 1036791 citations. The organization is also known as: UM & Universiti Malaya.
Topics: Population, Fiber laser, Laser, Ring (chemistry), Electrolyte
Papers published on a yearly basis
Papers
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University of Malaya1, Central Food Technological Research Institute2, Thailand National Science and Technology Development Agency3, Mahidol University4, Korea Research Institute of Bioscience and Biotechnology5, University of the Philippines6, Academia Sinica7, Agency for Science, Technology and Research8, Peking Union Medical College9, National Institute of Advanced Industrial Science and Technology10, Universiti Sains Malaysia11, Chinese National Human Genome Center12, Tokai University13, Fudan University14, Chiang Mai University15, Thermo Fisher Scientific16, Soongsil University17, Eulji University18, University of Tokyo19, National University of Singapore20, Indian Statistical Institute21, Eijkman Institute for Molecular Biology22, Nanyang Technological University23, University of the Ryukyus24, Health Sciences University of Hokkaido25, Monash University Malaysia Campus26, National Institutes of Health27
TL;DR: The results suggest that there may have been a single major migration of people into Asia and a subsequent south-to-north migration across the continent, and that genetic ancestry is strongly correlated with linguistic affiliations as well as geography.
Abstract: Asia harbors substantial cultural and linguistic diversity, but the geographic structure of genetic variation across the continent remains enigmatic. Here we report a large-scale survey of autosomal variation from a broad geographic sample of Asian human populations. Our results show that genetic ancestry is strongly correlated with linguistic affiliations as well as geography. Most populations show relatedness within ethnic/linguistic groups, despite prevalent gene flow among populations. More than 90% of East Asian (EA) haplotypes could be found in either Southeast Asian (SEA) or Central-South Asian (CSA) populations and show clinal structure with haplotype diversity decreasing from south to north. Furthermore, 50% of EA haplotypes were found in SEA only and 5% were found in CSA only, indicating that SEA was a major geographic source of EA populations.
545 citations
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TL;DR: In this article, independent corporate boards of Hong Kong firms provide effective monitoring of earnings management, which suggests that despite differences in institutional environments, corporate board independence is important to ensure high-quality financial reporting.
545 citations
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TL;DR: In this paper, a comprehensive literature in terms of Thesis (MS and PhD), peer reviewed journals papers, conference proceedings, books, reports, websites for emission generation and mitigation technique has been presented in this paper.
Abstract: The cement subsector consumes approximately 12–15% of the total industrial energy use. Therefore, this subsector releases CO2 emissions to the atmosphere as a result of burning fossil fuels to produce energy needed for the cement manufacturing process. The cement industry contributes about 7% of the total worldwide CO2 emissions. This study complied a comprehensive literature in terms of Thesis (MS and PhD), peer reviewed journals papers, conference proceedings, books, reports, websites for emission generation and mitigation technique. Emission released associated with the burning of fuels have been presented in this paper. Different sources of emissions in a cement industry has been identified and presented in this study. Different techniques to reduce CO2 emissions from the cement manufacturing industries are reviewed and presented in this paper. The major techniques are: capture and storage CO2 emissions, reducing clinker/cement ratio by replacing clinker with different of additives and using alternative fuels instead of fossil fuels. Apart from these techniques, various energy savings measures in cement industries expected to reduce indirect emissions released to the atmosphere. Based on review results it was found that sizeable amount of emission can be mitigated using different techniques and energy savings measures.
543 citations
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TL;DR: The results offer an explanation for the heterogeneity of TKI responses across individuals and suggest the possibility of personalizing therapy with BH3 mimetics to overcome BIM-polymorphism–associated TKI resistance.
Abstract: Tyrosine kinase inhibitors (TKIs) elicit high response rates among individuals with kinase-driven malignancies, including chronic myeloid leukemia (CML) and epidermal growth factor receptor-mutated non-small-cell lung cancer (EGFR NSCLC). However, the extent and duration of these responses are heterogeneous, suggesting the existence of genetic modifiers affecting an individual's response to TKIs. Using paired-end DNA sequencing, we discovered a common intronic deletion polymorphism in the gene encoding BCL2-like 11 (BIM). BIM is a pro-apoptotic member of the B-cell CLL/lymphoma 2 (BCL2) family of proteins, and its upregulation is required for TKIs to induce apoptosis in kinase-driven cancers. The polymorphism switched BIM splicing from exon 4 to exon 3, which resulted in expression of BIM isoforms lacking the pro-apoptotic BCL2-homology domain 3 (BH3). The polymorphism was sufficient to confer intrinsic TKI resistance in CML and EGFR NSCLC cell lines, but this resistance could be overcome with BH3-mimetic drugs. Notably, individuals with CML and EGFR NSCLC harboring the polymorphism experienced significantly inferior responses to TKIs than did individuals without the polymorphism (P = 0.02 for CML and P = 0.027 for EGFR NSCLC). Our results offer an explanation for the heterogeneity of TKI responses across individuals and suggest the possibility of personalizing therapy with BH3 mimetics to overcome BIM-polymorphism-associated TKI resistance.
537 citations
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TL;DR: An overview on the diversity of biomass, technological approaches and microbial contribution to the conversion of lignocellulosic biomass (LCB) into ethanol can be found in this paper.
Abstract: Bioethanol is one of the most promising and eco-friendly alternatives to fossil fuels, which is produced from renewable sources. Although almost all the current fuel ethanol is generated from edible sources (sugars and starch), lignocellulosic biomass (LCB) has drawn much attention in recent times. However, the conversion efficiency as well as ethanol yield of the biomass differs greatly with respect to the source and nature of LCB, primarily due to the variation in lignocellulosic content. Two major polysaccharides in LCB, namely, cellulose and hemicellulose firmly link to lignin and form a complex lignocellulosic network, which is highly robust and recalcitrant to depolymerization. For this reason, generation of ethanol from LCB requires a complicated conversion process that has made it commercially non-competitive. As attempts to exploit LCBs into commercial ethanol production, recent research efforts have been devoted to the techno-economic improvements of the overall conversion process, in addition to screen out promising feedstocks. This review paper presents an overview on the diversity of biomass, technological approaches and microbial contribution to the conversion of LCB into ethanol.
536 citations
Authors
Showing all 25327 results
Name | H-index | Papers | Citations |
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Diederick E. Grobbee | 155 | 1051 | 122748 |
Intae Yu | 134 | 1372 | 89870 |
Ovsat Abdinov | 129 | 864 | 78489 |
Jyothsna Rani Komaragiri | 129 | 1097 | 82258 |
Odette Benary | 128 | 844 | 74238 |
Paul M. Vanhoutte | 127 | 868 | 62177 |
Irene Vichou | 126 | 762 | 72520 |
Ian O. Ellis | 126 | 1051 | 75435 |
Louisa Degenhardt | 126 | 798 | 139683 |
Matthew Jones | 125 | 1161 | 96909 |
Andrius Juodagalvis | 118 | 1069 | 67138 |
Martin Ravallion | 115 | 570 | 55380 |
R. St. Denis | 112 | 921 | 65326 |
Xiao-Ming Chen | 108 | 596 | 42229 |
A. Yurkewicz | 106 | 514 | 51537 |