Institution
University of Maribor
Education•Maribor, Slovenia•
About: University of Maribor is a education organization based out in Maribor, Slovenia. It is known for research contribution in the topics: Population & KEKB. The organization has 3987 authors who have published 13077 publications receiving 258339 citations. The organization is also known as: Univerza v Mariboru.
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Wellcome Trust Sanger Institute1, Broad Institute2, University of Groningen3, University of Pittsburgh4, Cedars-Sinai Medical Center5, Yale University6, University of Cambridge7, University of Chicago8, Harvard University9, Katholieke Universiteit Leuven10, University of Liège11, King's College London12, Université de Montréal13, New Jersey Institute of Technology14, Cleveland Clinic15, Peninsula College of Medicine and Dentistry16, Université libre de Bruxelles17, Aarhus University18, University of Adelaide19, University of Kiel20, Flinders University21, McGill University22, Ludwig Maximilian University of Munich23, Charité24, Icahn School of Medicine at Mount Sinai25, University of Bonn26, Karolinska Institutet27, Torbay Hospital28, University of Auckland29, Christchurch Hospital30, Imperial College London31, Queen's University32, University of Oslo33, Lithuanian University of Health Sciences34, Emory University35, Casa Sollievo della Sofferenza36, Ghent University37, University of Western Australia38, University of Edinburgh39, Queensland Health40, Newcastle University41, University of Dundee42, University of Manchester43, University of Amsterdam44, University of Maribor45, Royal Hospital for Sick Children46, Guy's and St Thomas' NHS Foundation Trust47, QIMR Berghofer Medical Research Institute48, Norfolk and Norwich University Hospital49, Leiden University50, Technische Universität München51, University of Toronto52, University of Pennsylvania53, Johns Hopkins University54, University of Queensland55
TL;DR: A meta-analysis of Crohn’s disease and ulcerative colitis genome-wide association scans is undertaken, followed by extensive validation of significant findings, with a combined total of more than 75,000 cases and controls.
Abstract: Crohn's disease and ulcerative colitis, the two common forms of inflammatory bowel disease (IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other populations. Genome-wide association studies and subsequent meta-analyses of these two diseases as separate phenotypes have implicated previously unsuspected mechanisms, such as autophagy, in their pathogenesis and showed that some IBD loci are shared with other inflammatory diseases. Here we expand on the knowledge of relevant pathways by undertaking a meta-analysis of Crohn's disease and ulcerative colitis genome-wide association scans, followed by extensive validation of significant findings, with a combined total of more than 75,000 cases and controls. We identify 71 new associations, for a total of 163 IBD loci, that meet genome-wide significance thresholds. Most loci contribute to both phenotypes, and both directional (consistently favouring one allele over the course of human history) and balancing (favouring the retention of both alleles within populations) selection effects are evident. Many IBD loci are also implicated in other immune-mediated disorders, most notably with ankylosing spondylitis and psoriasis. We also observe considerable overlap between susceptibility loci for IBD and mycobacterial infection. Gene co-expression network analysis emphasizes this relationship, with pathways shared between host responses to mycobacteria and those predisposing to IBD.
4,094 citations
University of California, Santa Barbara1, University of Texas at Austin2, Dresden University of Technology3, University of Wrocław4, University of Tartu5, Gulu University6, Middle East University7, Stockholm University8, University of the Punjab9, University of Nigeria, Nsukka10, Istanbul University11, Franklin & Marshall College12, Norwegian University of Science and Technology13, University of Algiers14, Australian National University15, Russian State University for the Humanities16, Russian Academy of Sciences17, İzmir University of Economics18, University of Social Sciences and Humanities19, Université catholique de Louvain20, Ankara University21, Pontifical Catholic University of Peru22, Cumhuriyet University23, University of the Republic24, ISCTE – University Institute of Lisbon25, The Chinese University of Hong Kong26, National Autonomous University of Mexico27, University of Pécs28, University of Constantine the Philosopher29, University of Maribor30, University of Zagreb31, University of Malaya32, Central University of Finance and Economics33, University of Crete34, University of Primorska35, Institute of Molecular and Cell Biology36, University of Amsterdam37, Catholic University of the Sacred Heart38, VU University Amsterdam39, University of Granada40, University of Delhi41, University of Havana42, Pontifical Catholic University of Rio de Janeiro43, University of Vienna44, Universiti Utara Malaysia45, Vilnius University46, University of British Columbia47, University of Sussex48, Romanian Academy49, Slovak Academy of Sciences50, Comenius University in Bratislava51, University of Monterrey52, SAS Institute53, DHA Suffa University54, Pontifical Catholic University of Chile55, South-West University "Neofit Rilski"56, University of São Paulo57, Kyung Hee University58, University of Ljubljana59
TL;DR: This work combines this large cross-cultural sample with agent-based models to compare eight hypothesized models of human mating markets and finds that this cross-culturally universal pattern of mate choice is most consistent with a Euclidean model of mate preference integration.
Abstract: Humans express a wide array of ideal mate preferences. Around the world, people desire romantic partners who are intelligent, healthy, kind, physically attractive, wealthy, and more. In order for these ideal preferences to guide the choice of actual romantic partners, human mating psychology must possess a means to integrate information across these many preference dimensions into summaries of the overall mate value of their potential mates. Here we explore the computational design of this mate preference integration process using a large sample of n = 14,487 people from 45 countries around the world. We combine this large cross-cultural sample with agent-based models to compare eight hypothesized models of human mating markets. Across cultures, people higher in mate value appear to experience greater power of choice on the mating market in that they set higher ideal standards, better fulfill their preferences in choice, and pair with higher mate value partners. Furthermore, we find that this cross-culturally universal pattern of mate choice is most consistent with a Euclidean model of mate preference integration.
1,827 citations
TL;DR: In this article, the authors identify patterns in the decision, analysis, design, and implementation phases of DSL development and discuss domain analysis tools and language development systems that may help to speed up DSL development.
Abstract: Domain-specific languages (DSLs) are languages tailored to a specific application domain. They offer substantial gains in expressiveness and ease of use compared with general-purpose programming languages in their domain of application. DSL development is hard, requiring both domain knowledge and language development expertise. Few people have both. Not surprisingly, the decision to develop a DSL is often postponed indefinitely, if considered at all, and most DSLs never get beyond the application library stage.Although many articles have been written on the development of particular DSLs, there is very limited literature on DSL development methodologies and many questions remain regarding when and how to develop a DSL. To aid the DSL developer, we identify patterns in the decision, analysis, design, and implementation phases of DSL development. Our patterns improve and extend earlier work on DSL design patterns. We also discuss domain analysis tools and language development systems that may help to speed up DSL development. Finally, we present a number of open problems.
1,778 citations
TL;DR: A review of recent works on evolutionary games incorporating coevolutionary rules, as well as a didactic description of potential pitfalls and misconceptions associated with the subject can be found in this article.
Abstract: Prevalence of cooperation within groups of selfish individuals is puzzling in that it contradicts with the basic premise of natural selection. Favoring players with higher fitness, the latter is key for understanding the challenges faced by cooperators when competing with defectors. Evolutionary game theory provides a competent theoretical framework for addressing the subtleties of cooperation in such situations, which are known as social dilemmas. Recent advances point towards the fact that the evolution of strategies alone may be insufficient to fully exploit the benefits offered by cooperative behavior. Indeed, while spatial structure and heterogeneity, for example, have been recognized as potent promoters of cooperation, coevolutionary rules can extend the potentials of such entities further, and even more importantly, lead to the understanding of their emergence. The introduction of coevolutionary rules to evolutionary games implies, that besides the evolution of strategies, another property may simultaneously be subject to evolution as well. Coevolutionary rules may affect the interaction network, the reproduction capability of players, their reputation, mobility or age. Here we review recent works on evolutionary games incorporating coevolutionary rules, as well as give a didactic description of potential pitfalls and misconceptions associated with the subject. In addition, we briefly outline directions for future research that we feel are promising, thereby particularly focusing on dynamical effects of coevolutionary rules on the evolution of cooperation, which are still widely open to research and thus hold promise of exciting new discoveries.
1,671 citations
TL;DR: In this article, a narrow charmonium-like state produced in the exclusive decay process B+/--->K+/-pi(+)pi(-)J/psi has been observed, which has a mass of 3872.0+/-0.6(stat)+/- 0.5(syst) MeV.
Abstract: We report the observation of a narrow charmoniumlike state produced in the exclusive decay process B+/--->K+/-pi(+)pi(-)J/psi. This state, which decays into pi(+)pi(-)J/psi, has a mass of 3872.0+/-0.6(stat)+/-0.5(syst) MeV, a value that is very near the M(D0)+M(D(*0)) mass threshold. The results are based on an analysis of 152M B-Bmacr; events collected at the Upsilon(4S) resonance in the Belle detector at the KEKB collider. The signal has a statistical significance that is in excess of 10sigma.
1,294 citations
Authors
Showing all 4077 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Subhash Singh | 0 | 1 | 0 |
| N. A. Galibina | 0 | 1 | 0 |
| Jonnathan Santiago Berrezueta Guzmán | 0 | 3 | 0 |
| Nur Anni Haya | 0 | 1 | 0 |
| Pranab Dey | 0 | 1 | 0 |
| Jin Hyuk Kwon | 0 | 1 | 0 |
| Tanhaei Mohammad | 0 | 1 | 0 |
| Arthur Ragauskas | 0 | 1 | 0 |
| Marjeta Ciglenečki | 0 | 2 | 0 |
| A Cernej | 0 | 1 | 0 |
| Ivan Kavkler | 0 | 1 | 0 |
| Luka Hrgarek | 0 | 2 | 0 |
| D. Horvat | 0 | 1 | 0 |
| Andrej Zimšek | 0 | 1 | 0 |
| J. Avsec | 0 | 1 | 0 |