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Showing papers by "University of Maryland, College Park published in 2022"


Journal ArticleDOI
University of Exeter1, Max Planck Institute for Biogeochemistry2, Tyndall Centre3, Atlantic Oceanographic and Meteorological Laboratory4, Bjerknes Centre for Climate Research5, University of Maryland, College Park6, CICERO Center for International Climate Research7, Leibniz Institute for Baltic Sea Research8, University of Reading9, Leibniz Institute of Marine Sciences10, Goddard Space Flight Center11, Flanders Marine Institute12, Food and Agriculture Organization13, Alfred Wegener Institute for Polar and Marine Research14, National Oceanic and Atmospheric Administration15, University of East Anglia16, Japan Meteorological Agency17, ETH Zurich18, National Institute for Environmental Studies19, Karlsruhe Institute of Technology20, Laboratoire des Sciences du Climat et de l'Environnement21, Tula Foundation22, Hertie Institute for Clinical Brain Research23, Nanjing University of Information Science and Technology24, Wageningen University and Research Centre25, Tsinghua University26, University of Western Sydney27, Cooperative Institute for Research in Environmental Sciences28, University of Florida29, Center for Neuroscience and Regenerative Medicine30, Woods Hole Research Center31, Michigan State University32, Tianjin University33, Auburn University34, Jilin Medical University35, Max Planck Institute for Meteorology36, Imperial College London37, Centre National de Recherches Météorologiques38, University of Groningen39, Tohoku University40, Ludwig Maximilian University of Munich41, Bank for International Settlements42, Institut Pierre-Simon Laplace43, Environment Canada44, North West Agriculture and Forestry University45, Northwest A&F University46, Pacific Marine Environmental Laboratory47, Stanford University48, Utrecht University49
TL;DR: Friedlingstein et al. as mentioned in this paper presented and synthesized datasets and methodology to quantify the five major components of the global carbon budget and their uncertainties, including fossil CO2 emissions, land use and land-use change data and bookkeeping models.
Abstract: Abstract. Accurate assessment of anthropogenic carbon dioxide (CO2) emissions and their redistribution among the atmosphere, ocean, and terrestrial biosphere in a changing climate is critical to better understand the global carbon cycle, support the development of climate policies, and project future climate change. Here we describe and synthesize datasets and methodology to quantify the five major components of the global carbon budget and their uncertainties. Fossil CO2 emissions (EFOS) are based on energy statistics and cement production data, while emissions from land-use change (ELUC), mainly deforestation, are based on land use and land-use change data and bookkeeping models. Atmospheric CO2 concentration is measured directly, and its growth rate (GATM) is computed from the annual changes in concentration. The ocean CO2 sink (SOCEAN) is estimated with global ocean biogeochemistry models and observation-based data products. The terrestrial CO2 sink (SLAND) is estimated with dynamic global vegetation models. The resulting carbon budget imbalance (BIM), the difference between the estimated total emissions and the estimated changes in the atmosphere, ocean, and terrestrial biosphere, is a measure of imperfect data and understanding of the contemporary carbon cycle. All uncertainties are reported as ±1σ. For the first time, an approach is shown to reconcile the difference in our ELUC estimate with the one from national greenhouse gas inventories, supporting the assessment of collective countries' climate progress. For the year 2020, EFOS declined by 5.4 % relative to 2019, with fossil emissions at 9.5 ± 0.5 GtC yr−1 (9.3 ± 0.5 GtC yr−1 when the cement carbonation sink is included), and ELUC was 0.9 ± 0.7 GtC yr−1, for a total anthropogenic CO2 emission of 10.2 ± 0.8 GtC yr−1 (37.4 ± 2.9 GtCO2). Also, for 2020, GATM was 5.0 ± 0.2 GtC yr−1 (2.4 ± 0.1 ppm yr−1), SOCEAN was 3.0 ± 0.4 GtC yr−1, and SLAND was 2.9 ± 1 GtC yr−1, with a BIM of −0.8 GtC yr−1. The global atmospheric CO2 concentration averaged over 2020 reached 412.45 ± 0.1 ppm. Preliminary data for 2021 suggest a rebound in EFOS relative to 2020 of +4.8 % (4.2 % to 5.4 %) globally. Overall, the mean and trend in the components of the global carbon budget are consistently estimated over the period 1959–2020, but discrepancies of up to 1 GtC yr−1 persist for the representation of annual to semi-decadal variability in CO2 fluxes. Comparison of estimates from multiple approaches and observations shows (1) a persistent large uncertainty in the estimate of land-use changes emissions, (2) a low agreement between the different methods on the magnitude of the land CO2 flux in the northern extra-tropics, and (3) a discrepancy between the different methods on the strength of the ocean sink over the last decade. This living data update documents changes in the methods and datasets used in this new global carbon budget and the progress in understanding of the global carbon cycle compared with previous publications of this dataset (Friedlingstein et al., 2020, 2019; Le Quéré et al., 2018b, a, 2016, 2015b, a, 2014, 2013). The data presented in this work are available at https://doi.org/10.18160/gcp-2021 (Friedlingstein et al., 2021).

343 citations


Journal ArticleDOI
TL;DR: In this paper , a comprehensive research progress and in-depth understanding of the critical factors leading to the poor low-temperature performance of Li-ion batteries is provided; the distinctive challenges on the anodes, electrolytes, cathodes, and electrolyte-electrodes interphases are sorted out, with a special focus on Liion transport mechanism therein.
Abstract: With the highest energy density ever among all sorts of commercialized rechargeable batteries, Li-ion batteries (LIBs) have stimulated an upsurge utilization in 3C devices, electric vehicles, and stationary energy-storage systems. However, a high performance of commercial LIBs based on ethylene carbonate electrolytes and graphite anodes can only be achieved at above -20 °C, which restricts their applications in harsh environments. Here, a comprehensive research progress and in-depth understanding of the critical factors leading to the poor low-temperature performance of LIBs is provided; the distinctive challenges on the anodes, electrolytes, cathodes, and electrolyte-electrodes interphases are sorted out, with a special focus on Li-ion transport mechanism therein. Finally, promising strategies and solutions for improving low-temperature performance are highlighted to maximize the working-temperature range of the next-generation high-energy Li-ion/metal batteries.

123 citations


Journal ArticleDOI
Tracy Hussell1, Ramsey Sabit2, Rachel Upthegrove3, Daniel M. Forton4  +524 moreInstitutions (270)
TL;DR: The Post-hospitalisation COVID-19 study (PHOSP-COVID) as mentioned in this paper is a prospective, longitudinal cohort study recruiting adults (aged ≥18 years) discharged from hospital with COVID19 across the UK.

118 citations


Journal ArticleDOI
Pierre Friedlingstein1, Sönke Zaehle2, Corinne Le Quéré3, Christian Rödenbeck2, Bronte Tilbrook, Henry C. Bittig4, Denis Pierrot5, Louise Chini6, Jan Ivar Korsbakken7, Nicolas Bellouin8, Toste Tanhua9, Benjamin Poulter10, Peter Landschützer11, Francesco N. Tubiello12, Judith Hauck13, Are Olsen14, Vivek K. Arora15, Colm Sweeney16, Almut Arneth17, Marion Gehlen18, Hiroyuki Tsujino19, Daniel P. Kennedy20, Yosuke Iida19, Luke Gregor21, Jiye Zeng22, George C. Hurtt6, Nicolas Mayot23, Giacomo Grassi24, Shin-Ichiro Nakaoka22, Frédéric Chevallier18, Clemens Schwingshackl7, Wiley Evans25, Meike Becker26, Thomas Gasser27, Xu Yue28, Katie Pocock25, Stephanie Falk29, Thanos Gkritzalis11, Naiqing Pan30, Ingrid T. van der Laan-Luijkx31, Fraser Holding32, Carlos Gustavo Halaburda, Guanghong Zhou33, Peter Angele34, Jianling Chen1, e6gehqc68135, Carlos Muñoz Pérez23, Hiroshi Niinami36, Zongwe Binesikwe Crystal Hardy, Samuel Bourne37, Ralf Wüsthofen38, Paulo Brito, Christian Liguori39, Juan A. Martin-Ramos, Rattan Lal, kensetyrdhhtml2mdcom40, Staffan Furusten, Luca Miceli41, Eric Horster16, V. Miranda Chase, Field Palaeobiology Lab30, Living Tree Cbd Gummies, Lifeng Qin34, Yong Tang42, Annie Phillips43, Nathalie Fenouil26, mark, Karina Querne de Carvalho44, Satya Wydya Yenny, Maja Bak Herrie, Silvia Ravelli45, Andreas Gerster46, Denise Hottmann47, Wui-Lee Chang, Andreas Lutz48, Olga D. Vorob'eva49, Pallavi Banerjee1, Verónica Undurraga50, Jovan Babić, Michele D. Wallace9, Mònica Ginés-Blasi, 에볼루션카지노51, James Kelvin29, Christos Kontzinos1, Охунова Дилафруз Муминовна, Isabell Diekmann, Emily Burgoyne16, Vilemina Čenić52, Naomi Gikonyo26, CHAO LUAN21, Benjamin Pfluger53, Benjamin Pfluger54, A. J. Shields, Kobzos, Laszlo55, Adrian Langer56, Stuart L. Weinstein55, Abdullah ÖZÇELİK57, Yi Chen58, Anzhelika Solodka59, Valery Vasil'evich Kozlov60, Н.С. Рыжук, Roshan Vasant Shinde, Dr Sandeep Haribhau Wankhade, Dr Nitin Gajanan Shekapure, Mr Sachin Shrikant …61, Mylene Charon7, David Seibt62, Kobi Peled, None Rahmi52 
University of Exeter1, Max Planck Institute for Biogeochemistry2, Tyndall Centre3, Leibniz Institute for Baltic Sea Research4, Atlantic Oceanographic and Meteorological Laboratory5, University of Maryland, College Park6, CICERO Center for International Climate Research7, University of Reading8, Leibniz Institute of Marine Sciences9, Goddard Space Flight Center10, Flanders Marine Institute11, Food and Agriculture Organization12, Alfred Wegener Institute for Polar and Marine Research13, Geophysical Institute14, University of Victoria15, National Oceanic and Atmospheric Administration16, Karlsruhe Institute of Technology17, Laboratoire des Sciences du Climat et de l'Environnement18, Japan Meteorological Agency19, Indiana University20, ETH Zurich21, National Institute for Environmental Studies22, University of East Anglia23, European Commission24, Tula Foundation25, Bjerknes Centre for Climate Research26, Hertie Institute for Clinical Brain Research27, Nanjing University of Information Science and Technology28, Ludwig Maximilian University of Munich29, Auburn University30, Wageningen University and Research Centre31, University of Western Sydney32, Cooperative Institute for Research in Environmental Sciences33, Tsinghua University34, University of Florida35, Center for Neuroscience and Regenerative Medicine36, Woods Hole Research Center37, University of Alaska Fairbanks38, Princeton University39, Michigan State University40, University of Washington41, Appalachian State University42, Sun Yat-sen University43, Imperial College London44, University of Groningen45, University of Tennessee46, Washington University in St. Louis47, Jilin Medical University48, Tohoku University49, Rutgers University50, Centre for Research on Ecology and Forestry Applications51, Institut Pierre-Simon Laplace52, North West Agriculture and Forestry University53, Northwest A&F University54, Pacific Marine Environmental Laboratory55, Xi'an Jiaotong University56, Stanford University57, National Center for Atmospheric Research58, University of Edinburgh59, Max Planck Institute for Meteorology60, Utrecht University61, Oak Ridge National Laboratory62
TL;DR: Friedlingstein et al. as mentioned in this paper presented and synthesized data sets and methodologies to quantify the five major components of the global carbon budget and their uncertainties, including fossil CO2 emissions, land use and land-use change data and bookkeeping models.
Abstract: Abstract. Accurate assessment of anthropogenic carbon dioxide (CO2) emissions and their redistribution among the atmosphere, ocean, and terrestrial biosphere in a changing climate is critical to better understand the global carbon cycle, support the development of climate policies, and project future climate change. Here we describe and synthesize data sets and methodologies to quantify the five major components of the global carbon budget and their uncertainties. Fossil CO2 emissions (EFOS) are based on energy statistics and cement production data, while emissions from land-use change (ELUC), mainly deforestation, are based on land use and land-use change data and bookkeeping models. Atmospheric CO2 concentration is measured directly, and its growth rate (GATM) is computed from the annual changes in concentration. The ocean CO2 sink (SOCEAN) is estimated with global ocean biogeochemistry models and observation-based data products. The terrestrial CO2 sink (SLAND) is estimated with dynamic global vegetation models. The resulting carbon budget imbalance (BIM), the difference between the estimated total emissions and the estimated changes in the atmosphere, ocean, and terrestrial biosphere, is a measure of imperfect data and understanding of the contemporary carbon cycle. All uncertainties are reported as ±1σ. For the year 2021, EFOS increased by 5.1 % relative to 2020, with fossil emissions at 10.1 ± 0.5 GtC yr−1 (9.9 ± 0.5 GtC yr−1 when the cement carbonation sink is included), and ELUC was 1.1 ± 0.7 GtC yr−1, for a total anthropogenic CO2 emission (including the cement carbonation sink) of 10.9 ± 0.8 GtC yr−1 (40.0 ± 2.9 GtCO2). Also, for 2021, GATM was 5.2 ± 0.2 GtC yr−1 (2.5 ± 0.1 ppm yr−1), SOCEAN was 2.9 ± 0.4 GtC yr−1, and SLAND was 3.5 ± 0.9 GtC yr−1, with a BIM of −0.6 GtC yr−1 (i.e. the total estimated sources were too low or sinks were too high). The global atmospheric CO2 concentration averaged over 2021 reached 414.71 ± 0.1 ppm. Preliminary data for 2022 suggest an increase in EFOS relative to 2021 of +1.0 % (0.1 % to 1.9 %) globally and atmospheric CO2 concentration reaching 417.2 ppm, more than 50 % above pre-industrial levels (around 278 ppm). Overall, the mean and trend in the components of the global carbon budget are consistently estimated over the period 1959–2021, but discrepancies of up to 1 GtC yr−1 persist for the representation of annual to semi-decadal variability in CO2 fluxes. Comparison of estimates from multiple approaches and observations shows (1) a persistent large uncertainty in the estimate of land-use change emissions, (2) a low agreement between the different methods on the magnitude of the land CO2 flux in the northern extratropics, and (3) a discrepancy between the different methods on the strength of the ocean sink over the last decade. This living data update documents changes in the methods and data sets used in this new global carbon budget and the progress in understanding of the global carbon cycle compared with previous publications of this data set. The data presented in this work are available at https://doi.org/10.18160/GCP-2022 (Friedlingstein et al., 2022b).

98 citations


Journal ArticleDOI
TL;DR: Wang et al. as mentioned in this paper used an extended ensemble learning of the space-time extremely randomized trees (STET) model, together with ground-based observations, remote sensing products, atmospheric reanalysis, and an emission inventory, to estimate ground-level ozone from solar radiation intensity and surface temperature.

87 citations


Journal ArticleDOI
TL;DR: In this paper , the authors synthesize knowledge accumulated in land system science, the integrated study of terrestrial social-ecological systems, into 10 hard truths that have strong, general, empirical support.
Abstract: Land use is central to addressing sustainability issues, including biodiversity conservation, climate change, food security, poverty alleviation, and sustainable energy. In this paper, we synthesize knowledge accumulated in land system science, the integrated study of terrestrial social-ecological systems, into 10 hard truths that have strong, general, empirical support. These facts help to explain the challenges of achieving sustainability in land use and thus also point toward solutions. The 10 facts are as follows: 1) Meanings and values of land are socially constructed and contested; 2) land systems exhibit complex behaviors with abrupt, hard-to-predict changes; 3) irreversible changes and path dependence are common features of land systems; 4) some land uses have a small footprint but very large impacts; 5) drivers and impacts of land-use change are globally interconnected and spill over to distant locations; 6) humanity lives on a used planet where all land provides benefits to societies; 7) land-use change usually entails trade-offs between different benefits—"win–wins" are thus rare; 8) land tenure and land-use claims are often unclear, overlapping, and contested; 9) the benefits and burdens from land are unequally distributed; and 10) land users have multiple, sometimes conflicting, ideas of what social and environmental justice entails. The facts have implications for governance, but do not provide fixed answers. Instead they constitute a set of core principles which can guide scientists, policy makers, and practitioners toward meeting sustainability challenges in land use.

85 citations


Journal ArticleDOI
TL;DR: In this paper, the static and dynamic lubrication parameters of the floating ring bearing (FRB) were investigated considering the effects of various coupling factors such as clearance ratio, vertical load and rotating speed.

62 citations


Journal ArticleDOI
TL;DR: In this paper , a robust cathode electrolyte interphase (CEI) in an all-fluorinated electrolyte, reversible planar gliding along the (003) plane in a single-crystalline LiCoO2 cathode is protected due to the prevention of element dissolution and electrolyte penetration.
Abstract: Single-crystalline cathode materials have attracted intensive interest in offering greater capacity retention than their polycrystalline counterparts by reducing material surfaces and phase boundaries. However, the single-crystalline LiCoO2 suffers severe structural instability and capacity fading when charged to high voltages (4.6 V) due to Co element dissolution and O loss, crack formation, and subsequent electrolyte penetration. Herein, by forming a robust cathode electrolyte interphase (CEI) in an all-fluorinated electrolyte, reversible planar gliding along the (003) plane in a single-crystalline LiCoO2 cathode is protected due to the prevention of element dissolution and electrolyte penetration. The robust CEI effectively controls the performance fading issue of the single-crystalline cathode at a high operating voltage of 4.6 V, providing new insights for improved electrolyte design of high-energy-density battery cathode materials.

60 citations


Journal ArticleDOI
TL;DR: In this paper , the authors survey the emerging field of multicaloric cooling and explore state-of-the-art caloric materials and systems (devices) that are responsive to multiple fields.
Abstract: Calls to minimize greenhouse gas emissions and demands for higher energy efficiency continue to drive research into alternative cooling and refrigeration technologies. The caloric effect is the reversible change in temperature and entropic states of a solid material subjected to one or more fields and can be exploited to achieve cooling. The field of caloric cooling has undergone a series of transformations over the past 50 years, bolstered by the advent of new materials and devices, and these developments have contributed to the emergence of multicalorics in the past decade. Multicaloric materials display one or more types of ferroic order that can give rise to multiple field-induced phase transitions that can enhance various aspects of caloric effects. These materials could open up new avenues for extracting heat and spearhead hitherto unknown technological applications. In this Review, we survey the emerging field of multicaloric cooling and explore state-of-the-art caloric materials and systems (devices) that are responsive to multiple fields. We present our vision of the future applications of multicaloric and caloric cooling and examine key factors that govern the overall system efficiency of the cooling devices. Multicaloric cooling promises environmentally friendly and high-efficiency refrigeration. In this Review, the authors discuss emerging multicaloric materials and their physics involving coexisting ferroic order parameters, examine key factors that govern the overall system efficiency of potential multicaloric devices and envision future applications.

53 citations


Journal ArticleDOI
TL;DR: In this paper , the authors summarize the stage characteristics of the multifunctional rural development and categorize China's rural areas by using both multi-factor comprehensive evaluation method and spatial analysis.

48 citations


Journal ArticleDOI
TL;DR: Recently, halide superionic conductors have emerged as promising solid electrolyte (SE) materials for all-solid-state batteries (ASSBs), owing to their inherent properties combining high Li+ conductivity, good chemical and electrochemical oxidation stabilities, and mechanical deformability as mentioned in this paper .
Abstract: Recently, halide superionic conductors have emerged as promising solid electrolyte (SE) materials for all-solid-state batteries (ASSBs), owing to their inherent properties combining high Li+ conductivity, good chemical and electrochemical oxidation stabilities, and mechanical deformability, compared to sulfide or oxide SEs. In this Review, recent advances in halide Li+- and Na+-conducting SEs are comprehensively summarized. After introducing the ionic diffusion mechanism and related governing factors of the crystal structures, we discuss the design strategies, such as the substitution and synthesis protocols, of the halide materials for further improving their properties. We review theoretical and experimental results on electrochemical stabilities and compatibilities with electrode materials. Moreover, we offer a critical assessment of the challenges and issues associated with the development of practical ASSB applications, such as cost considerations, stabilities in atmospheric air, aqueous solutions, and slurry-processing, and the wet-slurry or dry fabrication of sheet-type electrodes (or SE membranes) for large-format ASSBs. Based on these discussions, we provide a perspective on the future research directions of halide SEs, emphasizing the need for expanding the materials space.

Journal ArticleDOI
TL;DR: In this paper, a probabilistic deep learning approach based on an ensemble of deep convolutional neural networks (CNN) is proposed to regress canopy top height globally, and the model learns to extract robust features that generalize to unseen geographical regions and yields reliable estimates of predictive uncertainty.

Journal ArticleDOI
TL;DR: This article identifies key scientific and engineering advances needed to enable effective spoken language interaction with robotics, and makes 25 recommendations, involving eight general themes: putting human needs first, better modeling the social and interactive aspects of language, improving robustness, creating new methods for rapid adaptation, and improving research infrastructure and resources.

Journal ArticleDOI
01 Jan 2022
TL;DR: The construction of a tandem S-scheme heterojunction forms a built-in electric field at the interface between the catalysts and increases the photocatalytic reduction potential as mentioned in this paper .
Abstract: The construction of a tandem S-scheme heterojunction forms a built-in electric field at the interface between the catalysts and increases the photocatalytic reduction potential.

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TL;DR: A new dynamic probabilistic risk assessment methodology is proposed that employs a new exploration strategy to generate risky scenarios and is used to perform risk assessment of a Space Shuttle ascent phase.

Journal ArticleDOI
TL;DR: The first Cloud Masking Intercomparison Exercise (CMIX) as discussed by the authors was conducted within the Committee Earth Observation Satellites (CEOS) Working Group on Calibration & Validation (WGCV).


Journal ArticleDOI
TL;DR: In this paper, the authors apply a crowdsourcing approach and interpret the semantics of reviews for the top-rated courses on Coursera.org to explore the answers of what makes a great MOOC? What makes a hit?
Abstract: MOOC platforms have seen significant membership growth in recent years. MOOCs are leading the education world that has been digitized, remote, and highly competitive, and the competition is intense in the MOOC world. Based on the observation for top-rated MOOCs, this study proposes a research question, “What makes a great MOOC? What makes a hit?” To explore the answers, this study applies a crowdsourcing approach and interprets the semantics of reviews for the top-rated courses on Coursera.org. The paper has multiple steps and findings relevant to MOOC programs at universities worldwide. First, through exploratory analysis of learner reviews and expert judgment, this study identifies two distinct course categories focusing on learners' outcome intent, namely knowledge-seeking MOOCs and skill-seeking MOOCs. Further, this study uses a topical ontology of keywords and sentiment techniques to derive the intent of learners based on their comments. Through sentiment analysis and correlation analysis, it shows that knowledge-seeking MOOCs are driven by the quality of course design and materials. Skill-seeking MOOCs are driven by the instructor and their ability to present lectures and integrate course materials and assignments. This crowdsourcing method obtains the insights from large samples of learners’ reviews without the priming or self-selection biases of open surveys or interviews. The findings demonstrate the effectiveness of leveraging online learner reviews and offer practical implications for what truly “makes a hit” for top-rated MOOCs.

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TL;DR: Aerosol-cloud interactions (ACI) are considered to be the most uncertain driver of present-day radiative forcing due to human activities as discussed by the authors , and using correlations to infer causality can be challenging when meteorological variability also drives both aerosol and cloud changes independently.
Abstract: Aerosol-cloud interactions (ACIs) are considered to be the most uncertain driver of present-day radiative forcing due to human activities. The nonlinearity of cloud-state changes to aerosol perturbations make it challenging to attribute causality in observed relationships of aerosol radiative forcing. Using correlations to infer causality can be challenging when meteorological variability also drives both aerosol and cloud changes independently. Natural and anthropogenic aerosol perturbations from well-defined sources provide "opportunistic experiments" (also known as natural experiments) to investigate ACI in cases where causality may be more confidently inferred. These perturbations cover a wide range of locations and spatiotemporal scales, including point sources such as volcanic eruptions or industrial sources, plumes from biomass burning or forest fires, and tracks from individual ships or shipping corridors. We review the different experimental conditions and conduct a synthesis of the available satellite datasets and field campaigns to place these opportunistic experiments on a common footing, facilitating new insights and a clearer understanding of key uncertainties in aerosol radiative forcing. Cloud albedo perturbations are strongly sensitive to background meteorological conditions. Strong liquid water path increases due to aerosol perturbations are largely ruled out by averaging across experiments. Opportunistic experiments have significantly improved process-level understanding of ACI, but it remains unclear how reliably the relationships found can be scaled to the global level, thus demonstrating a need for deeper investigation in order to improve assessments of aerosol radiative forcing and climate change.

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TL;DR: In this article, microbubble (MB) ultrasound contrast agents in conjunction with ultrasound energy to locally increase the permeability of brain vessels and modulate the brain TME are discussed.

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TL;DR: In this article , 14 virus concentration protocols based on centrifugation, filtration, polyethylene glycol (PEG) precipitation and ultrafiltration were tested for their efficacy for the quantification of SARS-CoV-2 in wastewater samples.

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TL;DR: In this paper , the authors present a novel 2019 global land cover, land use, and ecozone map derived from Landsat satellite imagery and topographical data using derived image feature spaces and algorithms suited per theme.
Abstract: Abstract The conversion of natural land cover into human-dominated land use systems has significant impacts on the environment. Global mapping and monitoring of human-dominated land use extent via satellites provides an empirical basis for assessing land use pressures. Here, we present a novel 2019 global land cover, land use, and ecozone map derived from Landsat satellite imagery and topographical data using derived image feature spaces and algorithms suited per theme. From the map, we estimate the spatial extent and dispersion of land use disaggregated by climate domain and ecozone, where dispersion is the mean distance of land use to all land within a subregion. We find that percent of area under land use and distance to land use follow a power law that depicts an increasingly random spatial distribution of land use as it extends across lands of comparable development potential. For highly developed climate/ecozones, such as temperate and sub-tropical terra firma vegetation on low slopes, area under land use is contiguous and remnant natural land cover have low areal extent and high fragmentation. The tropics generally have the greatest potential for land use expansion, particularly in South America. An exception is Asian humid tropical terra firma vegetated lowland, which has land use intensities comparable to that of temperate breadbaskets such as the United States’ corn belt. Wetland extent is inversely proportional to land use extent within climate domains, indicating historical wetland loss for temperate, sub-tropical, and dry tropical biomes. Results highlight the need for planning efforts to preserve natural systems and associated ecosystem services. The demonstrated methods will be implemented operationally in quantifying global land change, enabling a monitoring framework for systematic assessments of the appropriation and restoration of natural land cover.

DOI
14 Jan 2022
TL;DR: This work reviews one approach that relies on rigorously defined computational models to specify the links between linguistic features and neural signals and describes one such data set in detail in the Supplementary Appendix.
Abstract: Efforts to understand the brain bases of language face the mapping problem: at what level do linguistic computations and representations connect to human neurobiology? We review one approach to this problem that relies on rigorously defined computational models to specify the links between linguistic features and neural signals. Such tools can be used to estimate linguistic predictions, model linguistic features, or specify a sequence of processing steps that may be quantitatively fit to neural signals collected while participants use language. Progress has been helped by advances in machine learning, attention to linguistically interpretable models, and openly shared datasets that allow researchers to compare and contrast a variety of models. We describe one such dataset in detail in the supplementary materials.

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TL;DR: In this article, the presence of these nonlinear gusts are becoming more and more prevalent and they induce flow separation and other complexities when they interact with the lifting surfaces of air vehicles.
Abstract: Gusts of moderate and large magnitude induce flow separation and other complexities when they interact with the lifting surfaces of air vehicles. The presence of these nonlinear gusts are becoming ...

Journal ArticleDOI
TL;DR: In this paper, the authors reported the detection of SARS-CoV-2 in infected patients (mid-turbinate swabs and exhaled breath aerosol samples) in concentrations as low as 60 copies/mL of the virus in seconds by electrical transduction of the SARS CoV-1 S1 spike protein antigen via SARSCoV2 S 1 spike protein antibodies immobilized on bilayer quasi-freestanding epitaxial graphene without gate or signal amplification.

Journal ArticleDOI
TL;DR: In this article , the authors reported the detection of SARS-CoV-2 in infected patients (mid-turbinate swabs and exhaled breath aerosol samples) in concentrations as low as 60 copies/mL of the virus in seconds by electrical transduction of the SARS CoV-1 S1 spike protein antigen via SARSCoV2 S 1 spike protein antibodies immobilized on bilayer quasi-freestanding epitaxial graphene without gate or signal amplification.

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TL;DR: In this paper , a hybrid catalyst 10%-CeO2/Mo-S exhibiting the best hydrogen generation ability (4.3 mmol h-1g-1) was obtained by optimizing the content of CeO2 in 10%-COMS.

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TL;DR: In this paper , the authors derive constraints using model-independent parameterizations of the dark matter--electron and dark matter-proton interaction cross sections and map these constraints onto concrete dark matter models, which are complementary to other probes of dark matter interactions with ordinary matter, such as direct detection, big bang nucleosynthesis, various astrophysical systems, and accelerator-based experiments.

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TL;DR: The Needs-to-Goals Gap as discussed by the authors ) is a framework that connects the utility of multi-informant data with the reality that services often target an array of needs within and across contexts.

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TL;DR: In this article , a double-gray general circulation model (GCM) and ray-striking radiative transfer were used to diagnose the high-resolution transmission spectrum of exoplanet WASP-76b.
Abstract: High-resolution spectra are unique indicators of three-dimensional processes in exoplanetary atmospheres. For instance, in 2020, Ehrenreich et al. reported transmission spectra from the ESPRESSO spectrograph yielding an anomalously large Doppler blueshift from the ultra-hot Jupiter WASP-76b. Interpretations of these observations invoke toy model depictions of gas-phase iron condensation in lower-temperature regions of the planet's atmosphere. In this work, we forward model the atmosphere of WASP-76b with double-gray general circulation models (GCMs) and ray-striking radiative transfer to diagnose the planet's high-resolution transmission spectrum. We confirm that a physical mechanism driving strong east-west asymmetries across the terminator must exist to reproduce large Doppler blueshifts in WASP-76b's transmission spectrum. We identify low atmospheric drag and a deep radiative-convective boundary as necessary components of our GCM to produce this asymmetry (the latter is consistent with existing Spitzer phase curves). However, we cannot reproduce either the magnitude or the time-dependence of the WASP-76b Doppler signature with gas-phase iron condensation alone. Instead, we find that high-altitude, optically thick clouds composed of $\rm Al_2O_3$, Fe, or $\rm Mg_2SiO_4$ provide reasonable fits to the Ehrenreich et al. observations -- with marginal contributions from condensation. This fit is further improved by allowing a small orbital eccentricity ($e \approx 0.017$), consistent with prior WASP-76b orbital constraints. We additionally validate our forward-modeled spectra by reproducing lines of nearly all species detected in WASP-76b by Tabernero et al. 2021. Our procedure's success in diagnosing phase-resolved Doppler shifts demonstrates the benefits of physical, self-consistent, three-dimensional simulations in modeling high-resolution spectra of exoplanet atmospheres.