Institution
University of Massachusetts Amherst
Education•Amherst Center, Massachusetts, United States•
About: University of Massachusetts Amherst is a education organization based out in Amherst Center, Massachusetts, United States. It is known for research contribution in the topics: Population & Galaxy. The organization has 37274 authors who have published 83965 publications receiving 3834996 citations. The organization is also known as: UMass Amherst & Massachusetts State College.
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07 Dec 2009TL;DR: The prior structure advocated substantially increases the robustness of topic models to variations in the number of topics and to the highly skewed word frequency distributions common in natural language.
Abstract: Implementations of topic models typically use symmetric Dirichlet priors with fixed concentration parameters, with the implicit assumption that such "smoothing parameters" have little practical effect. In this paper, we explore several classes of structured priors for topic models. We find that an asymmetric Dirichlet prior over the document-topic distributions has substantial advantages over a symmetric prior, while an asymmetric prior over the topic-word distributions provides no real benefit. Approximation of this prior structure through simple, efficient hyperparameter optimization steps is sufficient to achieve these performance gains. The prior structure we advocate substantially increases the robustness of topic models to variations in the number of topics and to the highly skewed word frequency distributions common in natural language. Since this prior structure can be implemented using efficient algorithms that add negligible cost beyond standard inference techniques, we recommend it as a new standard for topic modeling.
691 citations
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TL;DR: The present study compared 172 adults diagnosed with ADHD with 30 adults referred to the same adult ADHD clinic who were not so diagnosed to suggest that ADHD in adults is associated with relatively specific risks for disruptive behavior disorders, school and job performance problems, and driving risks.
691 citations
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TL;DR: A survey of the major organizational paradigms used in multi-agent systems, which include hierarchies, holarchies, coalitions, teams, congregations, societies, federations, markets, and matrix organizations are presented.
Abstract: Many researchers have demonstrated that the organizational design employed by an agent system can have a significant, quantitative effect on its performance characteristics A range of organizational strategies have emerged from this line of research, each with different strengths and weaknesses In this article we present a survey of the major organizational paradigms used in multi-agent systems These include hierarchies, holarchies, coalitions, teams, congregations, societies, federations, markets, and matrix organizations We will provide a description of each, discuss their advantages and disadvantages, and provide examples of how they may be instantiated and maintained This summary will facilitate the comparative evaluation of organizational styles, allowing designers to first recognize the spectrum of possibilities, and then guiding the selection of an appropriate organizational design for a particular domain and environment
690 citations
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TL;DR: In this article, it was shown that there is only one class of network polymers for which the gel point coincides with the crossover, and the crossover cannot be used for detecting GP.
Abstract: Dynamic mechanical measurements allow direct determination of the instant at which a network polymer gels. In such an experiment, the evolution of G′(t,ω0) and G″ (t,ω0) is measured in small amplitude oscillatory shear as a function of cross-linking time t. The frequency ω0 is kept constant throughout. At the beginning of the experiment, G″ is orders of magnitude larger than G′, and at completion of reaction, this order is reversed. It recently has been suggested by Tung and Dynes that the gel point (GP) might occur at the time at which G′ and G″ cross each other. However, there is much dispute whether GP occurs exactly at the crossover or just somewhere in its vicinity. This study resolves the dispute by modeling the rheological behavior at GP: There is only one class of network polymers for which GP coincides with the crossover. This class of polymers exhibits, when reaching GP, power law relaxation G(t) ∼ t−n with a specific exponent value n = 1/2. Examples are stoichiometrically balanced network polymers and networks with excess cross-linker, however, only at temperatures much above the glass transition. Otherwise, the power law behavior would be masked by vitrification. Power law relaxation seems to be property of polymers at GP in general. However, some polymers have a different exponent value, n ≠ 1/2, in which case the crossover occurs before GP (for n 1/2); i.e. the crossover cannot be used for detecting GP. While there are no networks known to us with n 1/2. A new method is suggested for measuring GP of these imbalanced networks.
690 citations
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Institute for Systems Biology1, University of Washington2, University of Massachusetts Amherst3, University of Bath4, Northern Illinois University5, University of Wisconsin-Madison6, University of Pennsylvania7, University of Texas Health Science Center at Houston8, Ohio State University9, University of British Columbia10, Stanford University11, Marine Biological Laboratory12
TL;DR: Analysis of the genome sequence shows the presence of pathways for uptake and utilization of amino acids, active sodium-proton antiporter and potassium uptake systems, sophisticated photosensory and signal transduction pathways, and DNA replication, transcription, and translation systems resembling more complex eukaryotic organisms.
Abstract: We report the complete sequence of an extreme halophile, Halobacterium sp. NRC-1, harboring a dynamic 2,571,010-bp genome containing 91 insertion sequences representing 12 families and organized into a large chromosome and 2 related minichromosomes. The Halobacterium NRC-1 genome codes for 2,630 predicted proteins, 36% of which are unrelated to any previously reported. Analysis of the genome sequence shows the presence of pathways for uptake and utilization of amino acids, active sodium-proton antiporter and potassium uptake systems, sophisticated photosensory and signal transduction pathways, and DNA replication, transcription, and translation systems resembling more complex eukaryotic organisms. Whole proteome comparisons show the definite archaeal nature of this halophile with additional similarities to the Gram-positive Bacillus subtilis and other bacteria. The ease of culturing Halobacterium and the availability of methods for its genetic manipulation in the laboratory, including construction of gene knockouts and replacements, indicate this halophile can serve as an excellent model system among the archaea.
690 citations
Authors
Showing all 37601 results
Name | H-index | Papers | Citations |
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George M. Whitesides | 240 | 1739 | 269833 |
Joan Massagué | 189 | 408 | 149951 |
David H. Weinberg | 183 | 700 | 171424 |
David L. Kaplan | 177 | 1944 | 146082 |
Michael I. Jordan | 176 | 1016 | 216204 |
James F. Sallis | 169 | 825 | 144836 |
Bradley T. Hyman | 169 | 765 | 136098 |
Anton M. Koekemoer | 168 | 1127 | 106796 |
Derek R. Lovley | 168 | 582 | 95315 |
Michel C. Nussenzweig | 165 | 516 | 87665 |
Alfred L. Goldberg | 156 | 474 | 88296 |
Donna Spiegelman | 152 | 804 | 85428 |
Susan E. Hankinson | 151 | 789 | 88297 |
Bernard Moss | 147 | 830 | 76991 |
Roger J. Davis | 147 | 498 | 103478 |