Institution
University of Massachusetts Amherst
Education•Amherst Center, Massachusetts, United States•
About: University of Massachusetts Amherst is a education organization based out in Amherst Center, Massachusetts, United States. It is known for research contribution in the topics: Population & Galaxy. The organization has 37274 authors who have published 83965 publications receiving 3834996 citations. The organization is also known as: UMass Amherst & Massachusetts State College.
Papers published on a yearly basis
Papers
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TL;DR: The relationship between cell growth and the initiation and progression of events associated with differentiation has been a fundamental question challenging developmental biologists for more than a century as mentioned in this paper, and the relationship of growth and differentiation must be maintained and stringently regulated, both during development and throughout the life of the organism, to support tissue remodeling.
Abstract: I. Introduction A FUNCTIONAL relationship between cell growth and the initiation and progression of events associated with differentiation has been a fundamental question challenging developmental biologists for more than a century. In the case of bone, as observed with other cells and tissue, the relationship of growth and differentiation must be maintained and stringently regulated, both during development and throughout the life of the organism, to support tissue remodeling. For many years, bone was defined anatomically and examined largely in a descriptive manner by ultrastructural analysis and by biochemical and histochemical methods. These studies provided the basis for our understanding of bone tissue organization and orchestration of the progressive recruitment, proliferation, and differentiation of the various cellular components of bone tissue. Now, complemented by an increased knowledge of molecular mechanisms that are associated with and regulate expression of genes encoding phenotypic compone...
973 citations
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TL;DR: The 2 Micron All-Sky Survey (2MASS) as mentioned in this paper will observe over one-million galaxies and extended Galactic sources covering the entire sky at wavelenghts between 1 and 2 m.
Abstract: The 2 Micron All-Sky Survey (2MASS)will observe over one-million galaxies and extended Galactic sources covering the entire sky at wavelenghts between 1 and 2 m. Most of these galaxies, from 70 to 80%, will be newly catalogued objetcs.
972 citations
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TL;DR: The Institute of Food Technologists has issued a Scientific Status Summary to update readers on the applications of nanotechnology in the food industry as discussed by the authors, which can be found in this issue.
Abstract: The Institute of Food Technologists has issued this Scientific Status Summary to update readers on the applications of nanotechnology in the food industry.
969 citations
01 Jun 1994
TL;DR: In this article, the S = 1 interaction was introduced and the Kaon mixing and CP violation was investigated in the context of the large N expansion of the standard QCD model.
Abstract: Preface Inputs to the standard model Interactions of the standard model Symmetries and anomalies Introduction to effective Lagrangians Leptons Very low energy QCD - Pions and photons Introducing kaons and etas Kaons and the S=1 interaction Kaon mixing and CP violation The large N expansion Phenomenological models Baryon properties Hadron spectroscopy Weak interactions of heavy quarks The Higgs boson The electroweak gauge bosons Appendices References Index.
969 citations
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TL;DR: It is shown that proteins containing azidohomoalanine can be selectively modified in the presence of other cellular proteins by means of Staudinger ligation with triarylphosphine reagents and incorporation of azide-functionalized amino acids into proteins in vivo provides opportunities for protein modification under native conditions and selective labeling of proteins in the intracellular environment.
Abstract: The introduction of chemically unique groups into proteins by means of non-natural amino acids has numerous applications in protein engineering and functional studies. One method to achieve this involves the utilization of a non-natural amino acid by the cell's native translational apparatus. Here we demonstrate that a methionine surrogate, azidohomoalanine, is activated by the methionyl-tRNA synthetase of Escherichia coli and replaces methionine in proteins expressed in methionine-depleted bacterial cultures. We further show that proteins containing azidohomoalanine can be selectively modified in the presence of other cellular proteins by means of Staudinger ligation with triarylphosphine reagents. Incorporation of azide-functionalized amino acids into proteins in vivo provides opportunities for protein modification under native conditions and selective labeling of proteins in the intracellular environment.
964 citations
Authors
Showing all 37601 results
Name | H-index | Papers | Citations |
---|---|---|---|
George M. Whitesides | 240 | 1739 | 269833 |
Joan Massagué | 189 | 408 | 149951 |
David H. Weinberg | 183 | 700 | 171424 |
David L. Kaplan | 177 | 1944 | 146082 |
Michael I. Jordan | 176 | 1016 | 216204 |
James F. Sallis | 169 | 825 | 144836 |
Bradley T. Hyman | 169 | 765 | 136098 |
Anton M. Koekemoer | 168 | 1127 | 106796 |
Derek R. Lovley | 168 | 582 | 95315 |
Michel C. Nussenzweig | 165 | 516 | 87665 |
Alfred L. Goldberg | 156 | 474 | 88296 |
Donna Spiegelman | 152 | 804 | 85428 |
Susan E. Hankinson | 151 | 789 | 88297 |
Bernard Moss | 147 | 830 | 76991 |
Roger J. Davis | 147 | 498 | 103478 |