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Showing papers by "University of Massachusetts Boston published in 2012"


Journal ArticleDOI
TL;DR: In this paper, a color index (CI) was proposed to estimate surface chlorophyll-a concentrations (Chl) in the global ocean for Chl less than or equal to 0.25 milligrams per cubic meters.
Abstract: A new empirical algorithm is proposed to estimate surface chlorophyll-a concentrations (Chl) in the global ocean for Chl less than or equal to 0.25 milligrams per cubic meters (approximately 77% of the global ocean area). The algorithm is based on a color index (CI), defined as the difference between remote sensing reflectance (R(sub rs), sr(sup -1) in the green and a reference formed linearly between R(sub rs) in the blue and red. For low Chl waters, in situ data showed a tighter (and therefore better) relationship between CI and Chl than between traditional band-ratios and Chl, which was further validated using global data collected concurrently by ship-borne and SeaWiFS satellite instruments. Model simulations showed that for low Chl waters, compared with the band-ratio algorithm, the CI-based algorithm (CIA) was more tolerant to changes in chlorophyll-specific backscattering coefficient, and performed similarly for different relative contributions of non-phytoplankton absorption. Simulations using existing atmospheric correction approaches further demonstrated that the CIA was much less sensitive than band-ratio algorithms to various errors induced by instrument noise and imperfect atmospheric correction (including sun glint and whitecap corrections). Image and time-series analyses of SeaWiFS and MODIS/Aqua data also showed improved performance in terms of reduced image noise, more coherent spatial and temporal patterns, and consistency between the two sensors. The reduction in noise and other errors is particularly useful to improve the detection of various ocean features such as eddies. Preliminary tests over MERIS and CZCS data indicate that the new approach should be generally applicable to all existing and future ocean color instruments.

684 citations


Journal ArticleDOI
TL;DR: Patients accessed visit notes frequently, a large majority reported clinically relevant benefits and minimal concerns, and virtually all patients wanted the practice to continue, with doctors experiencing no more than a modest effect on their work lives.
Abstract: In this study, doctors and patients participated in a 1-year program that provided patients with electronic links to their doctors' notes. Most patients reported that the ability to read the notes ...

586 citations


Journal ArticleDOI
TL;DR: The results suggest that global measures of isolation, that fail to distinguish between social isolation and feelings of loneliness, may not detect the impact on physical and mental health in older adults.
Abstract: Objective: To examine the relationship of social isolation, loneliness and health outcomes among older adults. Methods: Using data from the Leave Behind Questionnaire of the Health and Retirement S...

509 citations


Journal ArticleDOI
TL;DR: In this article, the authors investigated the effect of brand fan pages on the customer-brand relationship and what motivates users to participate on brand fan page on social networks, and identified different values such as functional and hedonic content as drivers of fan page participation.
Abstract: Purpose – Brand fan pages on social networks have become very popular online services. However, empirical research on fan pages is still in its infancy. Therefore, the purpose of this study is to investigate the effect of fan pages on the customer‐brand relationship and what motivates users to participate.Design/methodology/approach – For this a framework was developed based on classical concepts of use and gratification theory, customer engagement, and involvement theory. The model is tested using a multi‐step approach of qualitative and quantitative methods.Findings – The paper can show a significant influence from online service usage behavior on the fan page on the customer‐brand relationship. Furthermore, the paper identifies different values such as functional and hedonic content as drivers of fan‐page participation.Research limitations/implications – The results are limited by the used data set, which is not representative for all industries and is cross‐sectional. Further research could build up a...

480 citations


Journal ArticleDOI
15 May 2012-PLOS ONE
TL;DR: This is the first time that large scale climatic and phenological changes at the landscape level have been documented for the Himalayas, confirming that the Himalayan regions are among the regions most vulnerable to climate change.
Abstract: Background Climate change in the Himalayas, a biodiversity hotspot, home of many sacred landscapes, and the source of eight largest rivers of Asia, is likely to impact the well-being of ∼20% of humanity. However, despite the extraordinary environmental, cultural, and socio-economic importance of the Himalayas, and despite their rapidly increasing ecological degradation, not much is known about actual changes in the two most critical climatic variables: temperature and rainfall. Nor do we know how changes in these parameters might impact the ecosystems including vegetation phenology. Methodology/Principal Findings By analyzing temperature and rainfall data, and NDVI (Normalized Difference Vegetation Index) values from remotely sensed imagery, we report significant changes in temperature, rainfall, and vegetation phenology across the Himalayas between 1982 and 2006. The average annual mean temperature during the 25 year period has increased by 1.5°C with an average increase of 0.06°C yr−1. The average annual precipitation has increased by 163 mm or 6.52 mmyr−1. Since changes in temperature and precipitation are immediately manifested as changes in phenology of local ecosystems, we examined phenological changes in all major ecoregions. The average start of the growing season (SOS) seems to have advanced by 4.7 days or 0.19 days yr−1 and the length of growing season (LOS) appears to have advanced by 4.7 days or 0.19 days yr−1, but there has been no change in the end of the growing season (EOS). There is considerable spatial and seasonal variation in changes in climate and phenological parameters. Conclusions/Significance This is the first time that large scale climatic and phenological changes at the landscape level have been documented for the Himalayas. The rate of warming in the Himalayas is greater than the global average, confirming that the Himalayas are among the regions most vulnerable to climate change.

469 citations


Journal ArticleDOI
TL;DR: In this article, the authors identify mechanisms by which extreme climatic events may influence the invasion process, from initial introduction through establishment and spread, and summarize how ECEs can enhance invasions by promoting the transport of propagules into new regions, by decreasing the resistance of native communities to establishment, and also sometimes by putting existing non-native species at a competitive disadvantage.
Abstract: Extreme climatic events (ECEs) – such as unusual heat waves, hurricanes, floods, and droughts – can dramatically affect ecological and evolutionary processes, and these events are projected to become more frequent and more intense with ongoing climate change. However, the implications of ECEs for biological invasions remain poorly understood. Using concepts and empirical evidence from invasion ecology, we identify mechanisms by which ECEs may influence the invasion process, from initial introduction through establishment and spread. We summarize how ECEs can enhance invasions by promoting the transport of propagules into new regions, by decreasing the resistance of native communities to establishment, and also sometimes by putting existing non-native species at a competitive disadvantage. Finally, we outline priority research areas and management approaches for anticipating future risks of unwanted invasions following ECEs. Given predicted increases in both ECE occurrence and rates of species introduction...

395 citations


Journal ArticleDOI
TL;DR: In this paper, the authors examined how warming and altered precipitation affected the rate and temperature sensitivity of heterotrophic respiration (Rh) at the Boston-area Climate Experiment, in Massachusetts, USA.
Abstract: Microbial decomposition of soil organic matter produces a major flux of CO2 from terrestrial ecosystems and can act as a feedback to climate change Although climate-carbon models suggest that warming will accelerate the release of CO2 from soils, the magnitude of this feedback is uncertain, mostly due to uncertainty in the temperature sensitivity of soil organic matter decomposition We examined how warming and altered precipitation affected the rate and temperature sensitivity of heterotrophic respiration (Rh) at the Boston-Area Climate Experiment, in Massachusetts, USA We measured Rh inside deep collars that excluded plant roots and litter inputs In this mesic ecosystem, Rh responded strongly to precipitation Drought reduced Rh, both annually and during the growing season Warming increased Rh only in early spring During the summer, when Rh was highest, we found evidence of threshold, hysteretic responses to soil moisture: Rh decreased sharply when volumetric soil moisture dropped below ~15% or exceeded ~26%, but Rh increased more gradually when soil moisture rose from the lower threshold The effect of climate treatments on the temperature sensitivity of Rh depended on the season Apparent Q10 decreased with high warming (~35 °C) in spring and fall Presumably due to limiting soil moisture, warming and precipitation treatments did not affect apparent Q10 in summer Drought decreased apparent Q10 in fall compared to ambient and wet precipitation treatments To our knowledge, this is the first field study to examine the response of Rh and its temperature sensitivity to the combined effects of warming and altered precipitation Our results highlight the complex responses of Rh to soil moisture, and to our knowledge identify for the first time the seasonal variation in the temperature sensitivity of microbial respiration in the field We emphasize the importance of adequately simulating responses such as these when modeling trajectories of soil carbon stocks under climate change scenarios

389 citations


Journal ArticleDOI
TL;DR: This study studies how different social movement and industry-driven standards organizations compete as well as collaborate over governance in transnational arenas and explains the dynamics of competing and collaborating non-state actors in constituting a standards market.
Abstract: The growing number of voluntary standards for governing transnational arenas is presenting standards organizations with a problem. While claiming that they are pursuing shared, overarching objectives, at the same time they are promoting their own respective standards that are increasingly similar. By developing the notion of ‘standards markets’, this paper examines this tension and studies how different social movement and industry-driven standards organizations compete as well as collaborate over governance in transnational arenas. Based on an in-depth case study of sustainability standards in the global coffee industry, we find that the ongoing co-existence of multiple standards is being promoted by the interplay between two countervailing mechanisms: convergence and differentiation. In conjunction, these mechanisms are enabling the emergence and persistence of a market for standards through what we describe as meta-standardization of sustainable practices. Meta-standardization leads to convergence at t...

382 citations


Journal ArticleDOI
TL;DR: In this article, a good agreement between mean yearly values of satellite retrievals and in situ measurements was found (R(exp 2 ) = 0.82), which is correlated to the spatial heterogeneity of surface albedo, stressing the relevance of land cover homogeneity when comparing point to pixel data.

261 citations


Journal ArticleDOI
TL;DR: Findings support the enrichment of large, rare CNVs in ADHD and implicate duplications at 15q13.3 as a novel risk factor for ADHD.
Abstract: OBJECTIVE: Attention deficit hyperactivity disorder (ADHD) is a common, highly heritable psychiatric disorder. Because of its multifactorial etiology, however, identifying the genes involved has been difficult. The authors followed up on recent findings suggesting that rare copy number variants (CNVs) may be important for ADHD etiology. METHOD: The authors performed a genome-wide analysis of large, rare CNVs (<1% population frequency) in children with ADHD (N=896) and comparison subjects (N=2,455) from the IMAGE II Consortium. RESULTS: The authors observed 1,562 individually rare CNVs >100 kb in size, which segregated into 912 independent loci. Overall, the rate of rare CNVs >100 kb was 1.15 times higher in ADHD case subjects relative to comparison subjects, with duplications spanning known genes showing a 1.2-fold enrichment. In accordance with a previous study, rare CNVs >500 kb showed the greatest enrichment (1.28-fold). CNVs identified in ADHD case subjects were significantly enriched for loci implicated in autism and in schizophrenia. Duplications spanning the CHRNA7 gene at chromosome 15q13.3 were associated with ADHD in single-locus analysis. This finding was consistently replicated in an additional 2,242 ADHD case subjects and 8,552 comparison subjects from four independent cohorts from the United Kingdom, the United States, and Canada. Presence of the duplication at 15q13.3 appeared to be associated with comorbid conduct disorder. CONCLUSIONS: These findings support the enrichment of large, rare CNVs in ADHD and implicate duplications at 15q13.3 as a novel risk factor for ADHD. With a frequency of 0.6% in the populations investigated and a relatively large effect size (odds ratio=2.22, 95% confidence interval=1.5–3.6), this locus could be an important contributor to ADHD etiology.

253 citations


Journal ArticleDOI
TL;DR: In this paper, the authors present an analysis of sixty transnational governance initiatives and assess the implications for our understanding of the roles of public and private actors, the legitimacy of governance 'beyond' the state, and the North-South dimensions of governing climate change.
Abstract: With this paper we present an analysis of sixty transnational governance initiatives and assess the implications for our understanding of the roles of public and private actors, the legitimacy of governance 'beyond' the state, and the North-South dimensions of governing climate change. In the first part of the paper we examine the notion of transnational governance and its applicability in the climate change arena, reflecting on the history and emergence of transnational governance initiatives in this issue area and key areas of debate. In the second part of the paper we present the findings from the database and its analysis. Focusing on three core issues, the roles of public and private actors in governing transnationally, the functions that such initiatives perform, and the ways in which accountability for governing global environmental issues might be achieved, we suggest that significant distinctions are emerging in the universe of transnational climate governance which may have considerable implications for the governing of global environmental issues. In conclusion, we reflect on these findings and the subsequent consequences for the governance of climate change.

Journal ArticleDOI
Eugenia E. Calle1, Susan M. Gapstur1, Alpa V. Patel, L. Dal Maso, R. Talamini, Angela Chetrit, Galit Hirsh-Yechezkel, Flora Lubin, Siegal Sadetzki, Emily Banks, Valerie Beral, Diana Bull, K. Callaghan, B Crossley, K Gaitskell, A. Goodill, Jane Green, C Hermon, Timothy J. Key, Kath Moser, G Reeves, Freddy Sitas2, R. Collins3, R. Doll3, Richard Peto3, Clicerio Gonzalez, N. Lee4, P. Marchbanks4, Howard W. Ory4, Herbert B. Peterson4, Phyllis A. Wingo4, N. Martin5, Tieng Pardthaisong5, S. Silpisornkosol5, C. Theetranont5, B. Boosiri6, S. Chutivongse6, P. Jimakorn6, Pramuan Virutamasen6, C. Wongsrichanalai6, Anne Tjønneland, Linda Titus-Ernstoff7, Tim Byers8, T E Rohan9, Berit Jul Mosgaard10, M. Vessey, D. Yeates, Jo L. Freudenheim11, Jenny Chang-Claude12, Rudolf Kaaks12, Kristin E. Anderson13, Aaron R. Folsom13, Kim Robien13, J. Hampton14, Polly A. Newcomb14, Mary Anne Rossing14, David B. Thomas14, N. S. Weiss14, Elio Riboli15, F. Clavel-Chapelon, Daniel W. Cramer16, Susan E. Hankinson16, Shelley S. Tworoger16, Silvia Franceschi17, C. La Vecchia18, Eva Negri18, H. O. Adami19, Cecilia Magnusson19, Tomas Riman19, Elisabete Weiderpass19, Alicja Wolk19, Leo J. Schouten20, P.A. van den Brandt20, N. Chantarakul21, Suporn Koetsawang21, D. Rachawat21, Domenico Palli, Amanda Black22, L A Brinton22, D. M. Freedman22, Patricia Hartge22, Ann W. Hsing22, Jr V. Lacey22, Robert N. Hoover22, Catherine Schairer22, Margaret I. Urban23, Sidsel Graff-Iversen24, Randi Selmer24, Chris Bain25, Adèle C. Green25, David M. Purdie25, Victor Siskind25, Penelope M. Webb25, K. Moysich26, Susan E. McCann26, P. Hannaford27, Kay Cr27, Colin W. Binns28, Andy H. Lee28, M. Zhang28, Roberta B. Ness29, P. C. Nasca30, Patricia F. Coogan31, Julie R. Palmer31, Lynn Rosenberg31, J. Kelsey32, R. Paffenbarger32, Alice S. Whittemore32, Klea Katsouyanni33, Antonia Trichopoulou33, Dimitrios Trichopoulos33, Anastasia Tzonou33, A. Dabancens34, L. Martinez34, R. Molina34, O. Salas34, Marc T. Goodman35, Galina Lurie35, Michael E. Carney35, Lynne R. Wilkens35, Linda Werner Hartman36, Jonas Manjer36, Håkan Olsson36, Jeane Ann Grisso37, Mark A. Morgan37, J. E. Wheeler37, C. H. Bunker38, Robert P. Edwards38, Francesmary Modugno38, P. H. M. Peeters39, John T. Casagrande40, Malcolm C. Pike40, R. K. Ross40, Anna H. Wu40, Anthony B. Miller41, Merethe Kumle, Inger T. Gram, Eiliv Lund, L. Mcgowan42, X. O. Shu43, Wei Zheng43, Timothy M.M. Farley44, S. Holck44, O. Meirik44, Harvey A. Risch45 
TL;DR: The excess of mucinous ovarian cancers in smokers is roughly counterbalanced by the deficit of endometrioid and clear-cell ovarian cancers, suggesting that smoking-related risks by tumour subtype is important for understanding ovarian carcinogenesis.
Abstract: Background Smoking has been linked to mucinous ovarian cancer, but its effects on other ovarian cancer subtypes and on overall ovarian cancer risk are unclear, and the findings from most studies with relevant data are unpublished To assess these associations, we review the published and unpublished evidence Methods Eligible epidemiological studies were identified by electronic searches, review articles, and discussions with colleagues Individual participant data for 28 114 women with and 94 942 without ovarian cancer from 51 epidemiological studies were analysed centrally, yielding adjusted relative risks (RRs) of ovarian cancer in smokers compared with never smokers Findings After exclusion of studies with hospital controls, in which smoking could have affected recruitment, overall ovarian cancer incidence was only slightly increased in current smokers compared with women who had never smoked (RR 106, 95% CI 101-111, p=001) Of 17 641 epithelial cancers with specified histology, 2314 (13%) were mucinous, 2360 (13%) endometrioid, 969 (5%) clear-cell, and 9086 (52%) serous Smoking-related risks varied substantially across these subtypes (p(heterogeneity)<00001) For mucinous cancers, incidence was increased in current versus never smokers (179, 95% CI 160-200, p<00001), but the increase was mainly in borderline malignant rather than in fully malignant tumours (225, 95% CI 191-265 vs 149, 128-173; p(heterogeneity)=001; almost half the mucinous tumours were only borderline malignant) Both endometrioid (081, 95% CI 072-092, p=0001) and clear-cell ovarian cancer risks (080, 95% CI 065-097, p=003) were reduced in current smokers, and there was no significant association for serous ovarian cancers (099, 95% CI 093-106, p=08) These associations did not vary significantly by 13 sociodemographic and personal characteristics of women including their body-mass index, parity, and use of alcohol, oral contraceptives, and menopausal hormone therapy Interpretation The excess of mucinous ovarian cancers in smokers, which is mainly of tumours of borderline malignancy, is roughly counterbalanced by the deficit of endometrioid and clear-cell ovarian cancers The substantial variation in smoking-related risks by tumour subtype is important for understanding ovarian carcinogenesis

Journal ArticleDOI
TL;DR: The authors describe a hybrid relational bureaucratic form with structures that embed three processes of reciprocal interrelating (relational coproduction, relational coordination, and relational leadership) into the roles of customers, workers, and managers.
Abstract: We describe a hybrid relational bureaucratic form with structures that embed three processes of reciprocal interrelating—relational coproduction, relational coordination, and relational leadership—into the roles of customers, workers, and managers. We show how these role-based relationships of shared goals, shared knowledge, and mutual respect foster participants' attentiveness to the situation and to one another, enabling the caring, timely, and knowledgeable responses found in the relational form, along with the scalability, replicability, and sustainability found in the bureaucratic form. Through these role-based relationships, relational bureaucracy promotes universalistic norms of caring for particular others.

Journal ArticleDOI
TL;DR: In this article, Chen et al. developed an approach to correct the MODIS hotspot magnitude with co-registered POLDER-3 data acquired at about the same time, and a global clumping index map has been produced using the corrected MODIS hotspot in the red band and optimized parameters.

Journal ArticleDOI
TL;DR: In this article, the application of heterogeneous catalysis combined with microwave irradiation in the synthesis of heterocyclic compounds is reviewed and the authors highlight the environmentally benign and sustainable nature of the combined microwave-assisted heterogeneous catalytic methods, highlighting the green aspects of individual synthetic approaches.

Journal ArticleDOI
TL;DR: In this paper, the authors review trends in the horticultural trade and invasion patterns of previously introduced species and show that novel species introductions from emerging horticulture trade partners are likely to rapidly increase invasion risk.
Abstract: Many non-native plants in the US have become problematic invaders of native and managed ecosystems, but a new generation of invasive species may be at our doorstep. Here, we review trends in the horticultural trade and invasion patterns of previously introduced species and show that novel species introductions from emerging horticultural trade partners are likely to rapidly increase invasion risk. At the same time, climate change and water restrictions are increasing demand for new types of species adapted to warm and dry environments. This confluence of forces could expose the US to a range of new invasive species, including many from tropical and semiarid Africa as well as the Middle East. Risk assessment strategies have proven successful elsewhere at identifying and preventing invasions, although some modifications are needed to address emerging threats. Now is the time to implement horticulture import screening measures to prevent this new wave of plant invasions.

Journal ArticleDOI
TL;DR: The influence of match length and re-matching on the effectiveness of school-based mentoring was studied in the context of a national, randomized study of 1,139 youth in Big Brothers Big Sisters programs.
Abstract: The influence of match length and re-matching on the effectiveness of school-based mentoring was studied in the context of a national, randomized study of 1,139 youth in Big Brothers Big Sisters programs. The sample included youth in grades four through nine from diverse racial and ethnic backgrounds. At the end of the year, youth in intact relationships showed significant academic improvement, while youth in matches that terminated prematurely showed no impact. Those who were re-matched after terminations showed negative impacts. Youth, mentor, and program characteristics associated with having an intact match were examined. Youth with high levels of baseline stress and those matched with college student mentors were likely to be in matches that terminated prematurely, while rejection-sensitive youth and mentors who had previous mentoring experience were more likely to be in intact relationships. Implications for research and practice are discussed.

Journal ArticleDOI
TL;DR: Results suggest that SOR emerges earlier than anxiety, and predicts later development of anxiety, in toddlers with autism spectrum disorders.
Abstract: This report focuses on the emergence of and bidirectional effects between anxiety and sensory over-responsivity (SOR) in toddlers with autism spectrum disorders (ASD). Participants were 149 toddlers with ASD and their mothers, assessed at 2 annual time points. A cross-lag analysis showed that anxiety symptoms increased over time while SOR remained relatively stable. SOR positively predicted changes in anxiety over and above child age, autism symptom severity, NVDQ, and maternal anxiety, but anxiety did not predict changes in SOR. Results suggest that SOR emerges earlier than anxiety, and predicts later development of anxiety.

Journal ArticleDOI
TL;DR: This study quantifies signal dynamic range and sensitivity parameters under uniform conditions for widely used past and current sensors in order to provide a reference for the design of future ocean color radiometers and to help design future missions such as the Geostationary Coastal and Air Pollution Events (GEO-CAPE) mission and the Pre-Aerosol-Clouds-Ecosystems (PACE) mission.
Abstract: Sensor design and mission planning for satellite ocean color measurements requires careful consideration of the signal dynamic range and sensitivity (specifically here signal-to-noise ratio or SNR) so that small changes of ocean properties (e.g., surface chlorophyll-a concentrations or Chl) can be quantified while most measurements are not saturated. Past and current sensors used different signal levels, formats, and conventions to specify these critical parameters, making it difficult to make cross-sensor comparisons or to establish standards for future sensor design. The goal of this study is to quantify these parameters under uniform conditions for widely used past and current sensors in order to provide a reference for the design of future ocean color radiometers. Using measurements from the Moderate Resolution Imaging Spectroradiometer onboard the Aqua satellite (MODISA) under various solar zenith angles (SZAs), typical (L(sub typical)) and maximum (L(sub max)) at-sensor radiances from the visible to the shortwave IR were determined. The Ltypical values at an SZA of 45 deg were used as constraints to calculate SNRs of 10 multiband sensors at the same L(sub typical) radiance input and 2 hyperspectral sensors at a similar radiance input. The calculations were based on clear-water scenes with an objective method of selecting pixels with minimal cross-pixel variations to assure target homogeneity. Among the widely used ocean color sensors that have routine global coverage, MODISA ocean bands (1 km) showed 2-4 times higher SNRs than the Sea-viewing Wide Field-of-view Sensor (Sea-WiFS) (1 km) and comparable SNRs to the Medium Resolution Imaging Spectrometer (MERIS)-RR (reduced resolution, 1.2 km), leading to different levels of precision in the retrieved Chl data product. MERIS-FR (full resolution, 300 m) showed SNRs lower than MODISA and MERIS-RR with the gain in spatial resolution. SNRs of all MODISA ocean bands and SeaWiFS bands (except the SeaWiFS near-IR bands) exceeded those from prelaunch sensor specifications after adjusting the input radiance to L(sub typical). The tabulated L(sub typical), L(sub max), and SNRs of the various multiband and hyperspectral sensors under the same or similar radiance input provide references to compare sensor performance in product precision and to help design future missions such as the Geostationary Coastal and Air Pollution Events (GEO-CAPE) mission and the Pre-Aerosol-Clouds-Ecosystems (PACE) mission currently being planned by the U.S. National Aeronautics and Space Administration (NASA).

Journal ArticleDOI
TL;DR: A developmental, dimensional approach shows promise for elucidating the boundaries between normative early childhood temper loss and emergent psychopathology.
Abstract: Background: Temper modulation problems are both a hallmark of early childhood and a common mental health concern. Thus, characterizing specific behavioral manifestations of temper loss along a dimension from normative misbehaviors to clinically significant problems is an important step toward identifying clinical thresholds. Methods: Parent-reported patterns of temper loss were delineated in a diverse community sample of preschoolers (n = 1,490). A developmentally sensitive questionnaire, the Multidimensional Assessment of Preschool Disruptive Behavior (MAP-DB), was used to assess temper loss in terms of tantrum features and anger regulation. Specific aims were: (a) document the normative distribution of temper loss in preschoolers from normative misbehaviors to clinically concerning temper loss behaviors, and test for sociodemographic differences; (b) use Item Response Theory (IRT) to model a Temper Loss dimension; and (c) examine associations of temper loss and concurrent emotional and behavioral problems. Results: Across sociodemographic subgroups, a unidimensional Temper Loss model fit the data well. Nearly all (83.7%) preschoolers had tantrums sometimes but only 8.6% had daily tantrums. Normative misbehaviors occurred more frequently than clinically concerning temper loss behaviors. Milder behaviors tended to reflect frustration in expectable contexts, whereas clinically concerning problem indicators were unpredictable, prolonged, and/or destructive. In multivariate models, Temper Loss was associated with emotional and behavioral problems. Conclusions: Parent reports on a developmentally informed questionnaire, administered to a large and diverse sample, distinguished normative and problematic manifestations of preschool temper loss. A developmental, dimensional approach shows promise for elucidating the boundaries between normative early childhood temper loss and emergent psychopathology. Keywords: Developmental psychopathology, temper tantrums, disruptive behavior, preschool psychopathology, dimensional.

Journal ArticleDOI
TL;DR: The results support the role of emotion knowledge in early school adjustment and academic success even with gender, age, and risk covaried, especially for boys, older preschoolers, and those at economic risk.
Abstract: Preschoolers (N=322 in preschool, 100 in kindergarten) were assessed longitudinally to examine the self-regulatory roots of emotion knowledge (labelling and situation) and the contributions of emotion knowledge to early school adjustment (i.e., including social, motivational, and behavioural indices), as well as moderation by age, gender, and risk. Age, gender, and risk differences in emotion knowledge were also examined. Emotion knowledge skills were found to be more advanced in older children and those not at economic risk, and in those with higher levels of self-regulation. Overall, the results support the role of emotion knowledge in early school adjustment and academic success even with gender, age, and risk covaried, especially for boys, older preschoolers, and those at economic risk.

Journal ArticleDOI
Valerie Beral, C Hermon, Richard Peto, G Reeves, Louise A. Brinton, Polly A. Marchbanks, Eva Negri, R. Ness, P. H. M. Peeters, M. Vessey, Eugenia E. Calle1, Susan M. Gapstur1, Alpa V. Patel1, L. Dal Maso, R. Talamini, Angela Chetrit, Galit Hirsh-Yechezkel, Flora Lubin, Siegal Sadetzki, Naomi E. Allen2, Diana Bull2, K. Callaghan2, B. Crossley2, K Gaitskell2, A. Goodill2, Jane Green2, Timothy J. Key2, K. Moser2, Rory Collins3, R. Doll3, Clicerio Gonzalez, N. Lee4, Howard W. Ory4, Herbert B. Peterson4, Phyllis A. Wingo4, N. Martin5, Tieng Pardthaisong5, S. Silpisornkosol5, C. Theetranont5, B. Boosiri6, S. Chutivongse6, P. Jimakorn6, Pramuan Virutamasen6, C. Wongsrichanalai6, Anne Tjønneland, Linda Titus-Ernstoff7, T. Byers8, T E Rohan9, Berit Jul Mosgaard10, D. Yeates, Jo L. Freudenheim11, Jenny Chang-Claude12, Rudolf Kaaks, Kristin E. Anderson13, Aaron R. Folsom13, Kim Robien13, Mary Anne Rossing14, David B. Thomas14, N. S. Weiss14, Elio Riboli15, F. Clavel-Chapelon16, Daniel W. Cramer17, Susan E. Hankinson17, Shelley S. Tworoger17, Silvia Franceschi18, C. La Vecchia19, Cecilia Magnusson20, Tomas Riman20, Elisabete Weiderpass20, Alicja Wolk20, Leo J. Schouten21, P.A. van den Brandt21, N. Chantarakul22, Suporn Koetsawang22, D. Rachawat22, Domenico Palli, Amanda Black23, A. Berrington de Gonzalez23, L A Brinton23, D. M. Freedman23, Patricia Hartge23, Ann W. Hsing23, James V. Lacey23, Robert N. Hoover23, Catherine Schairer23, Sidsel Graff-Iversen24, Randi Selmer24, Chris Bain25, Adèle C. Green25, David M. Purdie25, Victor Siskind25, Penelope M. Webb25, Susan E. McCann26, P. Hannaford27, Kay Cr27, Colin W. Binns28, Andy H. Lee28, M. Zhang28, Roberta B. Ness29, P. C. Nasca30, Patricia F. Coogan31, Julie R. Palmer31, Lynn Rosenberg31, J. Kelsey32, R. Paffenbarger32, Alice S. Whittemore32, Klea Katsouyanni33, Antonia Trichopoulou33, Dimitrios Trichopoulos33, Anastasia Tzonou33, A. Dabancens34, L. Martinez34, R. Molina34, O. Salas34, Marc T. Goodman35, Galina Lurie35, Michael E. Carney35, Lynne R. Wilkens35, Linda Werner Hartman36, Jonas Manjer36, Håkan Olsson36, Jeane Ann Grisso37, Mark A. Morgan37, J. E. Wheeler37, John T. Casagrande38, M. C. Pike38, R. K. Ross38, Anna H. Wu38, Anthony B. Miller39, Merethe Kumle40, Eiliv Lund40, L. Mcgowan41, Xiao-Ou Shu42, Wei Zheng42, Timothy M.M. Farley43, S. Holck43, O. Meirik43, Harvey A. Risch44 
TL;DR: A reanalysis of published and unpublished data from epidemiological studies examines the association between height, body mass index, and the risk of developing ovarian cancer.
Abstract: A reanalysis of published and unpublished data from epidemiological studies examines the association between height, body mass index, and the risk of developing ovarian cancer.

Journal ArticleDOI
TL;DR: Gene expression profiles revealed that AgNO(3) and AgNPs have distinct expression profiles suggesting different modes of toxicity, and two specific biomarkers were developed for the environmental detection of PVP AgNBP; although further verification under different environmental conditions is needed.
Abstract: Applications for silver nanomaterials in consumer products are rapidly expanding, creating an urgent need for toxicological examination of the exposure potential and ecological effects of silver nanoparticles (AgNPs). The integration of genomic techniques into environmental toxicology has presented new avenues to develop exposure biomarkers and investigate the mode of toxicity of novel chemicals. In the present study we used a 15k oligonucleotide microarray for Daphnia magna, a freshwater crustacean and common indicator species for toxicity, to differentiate between particle specific and ionic silver toxicity and to develop exposure biomarkers for citrate-coated and PVP-coated AgNPs. Gene expression profiles revealed that AgNO3 and AgNPs have distinct expression profiles suggesting different modes of toxicity. Major biological processes disrupted by the AgNPs include protein metabolism and signal transduction. In contrast, AgNO3 caused a downregulation of developmental processes, particularly in sensory d...

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TL;DR: In this article, the authors describe responses of an old-field herbaceous community to a factorial combination of four levels of warming (up to 4 °C) and three precipitation regimes (drought, ambient and rain addition) over two years.
Abstract: As Earth’s atmosphere accumulates carbon dioxide (CO2) and other greenhouse gases, Earth’s climate is expected to warm and precipitation patterns will likely change. The manner in which terrestrial ecosystems respond to climatic changes will in turn affect the rate of climate change. Here we describe responses of an old-field herbaceous community to a factorial combination of four levels of warming (up to 4 °C) and three precipitation regimes (drought, ambient and rain addition) over 2 years. Warming suppressed total production, shoot production, and species richness, but only in the drought treatment. Root production did not respond to warming, but drought stimulated the growth of deeper (> 10 cm) roots by 121% in 1 year. Warming and precipitation treatments both affected functional group composition, with C4 grasses and other annual and biennial species entering the C3 perennial-dominated community in ambient rainfall and rain addition treatments as well as in warmed treatments. Our results suggest that, in this mesic system, expected changes in temperature or large changes in precipitation alone can alter functional composition, but they have little effect on total herbaceous plant growth. However, drought limits the capacity of the entire system to withstand warming. The relative insensitivity of our study system to climate suggests that the herbaceous component of old-field communities will not dramatically increase production in response to warming or precipitation change, and so it is unlikely to provide either substantial increases in forage production or a meaningful negative feedback to climate change later this century.

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TL;DR: It is concluded that coming out may be associated with better health for LB women, and that parents who react nonsupportively when their children disclose LGB sexual orientation may contribute to children's increased odds of depression and hazardous substance use.
Abstract: This study investigated associations between coming out to parents, experiences of parental support, and self-reported health behaviors and conditions among a population-based sample of LGB individuals using data collected via the 2002 Massachusetts Behavioral Risk Factor Surveillance System (BRFSS; N = 177). We explored the following two hypotheses: 1) Lesbian, gay, and bisexual (LGB) individuals who had never disclosed their sexual orientation to a parent would report higher levels of risk behaviors and poorer health conditions than those who had come out; and 2) among LGB respondents who had come out to their parents, the individuals whose parents had reacted unsupportively would report higher levels of risk behaviors and poorer health conditions than those who had come out to parents who were supportive. Approximately two thirds of gay and bisexual (GB) males and lesbian and bisexual (LB) females reported receiving adequate social and emotional support from the parent to whom they first disclosed their sexual orientation. Among LB females, no disclosure of sexual orientation to a parent was associated with significantly elevated levels of past-month illicit drug use (AOR 12.16, 95% CI 2.87-51.54), fair or poor self-reported health status (AOR 5.71, 95% CI 1.45-22.51), and >15 days of depression in the past month (AOR 5.95, 95% CI 1.78-19.90), controlling for potential confounders. However, nondisclosure to a parent by GB males was not associated with greater odds of any of the health indicators assessed. Among GB males, those with unsupportive parents were significantly more likely to report current binge drinking (AOR 6.94, 95% CI 1.70-28.35) and >15 days depression in the past month (AOR 6.08, 95% CI 1.15-32.15), and among LB females, those with unsupportive parents were significantly more likely to report lifetime illicit drug use (AOR 11.43, 95% CI 2.50-52.30), and >15 days depression in the past month (AOR 5.51, 95% CI 1.36-22.36). We conclude that coming out may be associated with better health for LB women, and that parents who react nonsupportively when their children disclose LGB sexual orientation may contribute to children's increased odds of depression and hazardous substance use.

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TL;DR: Lamb et al. as mentioned in this paper discuss their disagreements and attempt to find some common ground in their viewpoints on girls' sexuality, finding that adequate sexuality education and media literacy education are vital to optimizing adolescent girls' sexual empowerment.
Abstract: Although all feminists tend to value empowered female sexuality, feminists often disagree, sometimes heatedly so, about the definition of and path to empowered sexuality among adolescent girls. In this theoretical paper, two feminists, who have previously expressed differing perspectives regarding adolescent girls’ sexual empowerment (Lamb 2010a, b; Peterson 2010), discuss their disagreements and attempt to find some common ground in their viewpoints on girls’ sexuality. A critical question related to sexual empowerment is whether empowerment includes a subjective sense of efficacy, desire, and pleasure. In other words, are girls sexually empowered if they feel that they are empowered? The authors identify three themes that make answering this question particularly challenging—age differences, exposure to sexualized media, and the pressure to please a partner. Despite these challenges, the authors identify several points of consensus, including agreeing that adequate sexuality education and media literacy education are vital to optimizing adolescent girls’ sexual empowerment.

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TL;DR: In this paper, the authors investigate the role of key industry and other stakeholders and their embeddedness in particular national contexts in driving the proliferation and co-evolution of sustainability standards, based on the case of the global coffee industry.

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TL;DR: Very preterm infant neurobehavior was associated with higher levels of developmental care both in ICC and in IPM, suggesting that these practices support better neurobehavioral stability.
Abstract: OBJECTIVE: To examine the relation between the neurobehavior of very preterm infants and the level of NICU quality of developmental care. METHODS: The neurobehavior of 178 very preterm infants (gestational age ≤29 weeks and/or birth weight ≤1500 g) from 25 NICUs participating in a large multicenter, longitudinal study (Neonatal Adequate Care for Quality of Life, NEO-ACQUA) was examined with a standardized neurobehavioral assessment, the NICU Network Neurobehavioral Scale (NNNS). A questionnaire, the NEO-ACQUA Quality of Care Checklist was used to evaluate the level of developmental care in each of the NICUs. A factor analyses applied to NEO-ACQUA Quality of Care Checklist produced 2 main factors: (1) the infant-centered care (ICC) index, which measures parents’ involvement in the care of their infant and other developmentally oriented care interventions, and (2) the infant pain management (IPM) index, which measures the NICU approach to and the procedures used for reducing infant pain. The relations between NNNS neurobehavioral scores and the 2 indexes were evaluated. RESULTS: Infants from NICUs with high scores on the ICC evidenced higher attention and regulation, less excitability and hypotonicity, and lower stress/abstinence NNNS scores than infants from low-care units. Infants from NICUs with high scores on the IPM evidenced higher attention and arousal, lower lethargy and nonoptimal reflexes NNNS scores than preterm infants from low-scoring NICUs. CONCLUSIONS: Very preterm infant neurobehavior was associated with higher levels of developmental care both in ICC and in IPM, suggesting that these practices support better neurobehavioral stability. * Abbreviations: ANCOVA — : analysis of covariance ANOVA — : analysis of variance ICC — : infant-centered care IPM — : infant pain management NEO-ACQUA study — : Neonatal Adequate Care for Quality of Life study NIDCAP — : Neonatal Individualized Developmental Care and Assessment Program NNNS — : NICU Network Neurobehavioral Scale QCC — : quality-of care checklist SES — : socioeconomic status VON-RA — : Vermont Oxford Network Risk Adjustment

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TL;DR: This investigation seeks to fill the gap in the literature by exploring the factors that influence use of force in encounters involving people with mental illness and evaluating whether CIT can reduce the likelihood of its use.
Abstract: The Crisis Intervention Team (CIT) program was first developed to reduce violence in encounters between the police and people with mental illness as well as provide improved access to mental health services. Although there is overwhelming popular support for this intervention, scant empirical evidence of its effectiveness is available—particularly whether the program can reduce the use of force. This investigation seeks to fill this gap in the literature by exploring the factors that influence use of force in encounters involving people with mental illness and evaluating whether CIT can reduce the likelihood of its use.

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TL;DR: In this article, the authors examine the extent to which resource endowments have influenced the evolution of technological and institutional innovations in Nepal's agricultural research and development, and reveal that Nepal has developed a novel multilevel institutional partnership, including collaboration with farmers and other non-governmental organizations in recent years.