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Institution

University of Milan

EducationMilan, Italy
About: University of Milan is a education organization based out in Milan, Italy. It is known for research contribution in the topics: Population & Transplantation. The organization has 58413 authors who have published 139784 publications receiving 4636354 citations. The organization is also known as: Università degli Studi di Milano & Statale.


Papers
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Journal ArticleDOI
TL;DR: The main features and statistics of the developed system, Virtual Computational Chemistry Laboratory, allowing the computational chemist to perform a comprehensive series of molecular indices/properties calculations and data analysis are reviewed.
Abstract: Internet technology offers an excellent opportunity for the development of tools by the cooperative effort of various groups and institutions. We have developed a multi-platform software system, Virtual Computational Chemistry Laboratory, http://www.vcclab.org, allowing the computational chemist to perform a comprehensive series of molecular indices/properties calculations and data analysis. The implemented software is based on a three-tier architecture that is one of the standard technologies to provide client-server services on the Internet. The developed software includes several popular programs, including the indices generation program, DRAGON, a 3D structure generator, CORINA, a program to predict lipophilicity and aqueous solubility of chemicals, ALOGPS and others. All these programs are running at the host institutes located in five countries over Europe. In this article we review the main features and statistics of the developed system that can be used as a prototype for academic and industry models.

1,377 citations

Journal ArticleDOI
TL;DR: In this paper, the dependence of the voltammetric surface charge q* on solution pH and potential scan rate has been investigated using a set of RuO2 electrodes prepared by thermal decomposition of RuCl3 at temperatures in the range 300-500°C.

1,367 citations

Journal ArticleDOI
TL;DR: Whether increasing the cardiac index to a supranormal level (cardiac-index group) or increasing mixed venous oxygen saturation to a normal level (oxygen-saturation group) would decrease morbidity and mortality among critically ill patients, as compared with a control group in which the target was a normal cardiac index.
Abstract: Background Hemodynamic therapy to raise the cardiac index and oxygen delivery to supranormal levels may improve outcomes in critically ill patients. We studied whether increasing the cardiac index to a supranormal level (cardiac-index group) or increasing mixed venous oxygen saturation to a normal level (oxygen-saturation group) would decrease morbidity and mortality among critically ill patients, as compared with a control group in which the target was a normal cardiac index. Methods A total of 10,726 patients in 56 intensive care units were screened, among whom 762 patients belonging to predefined diagnostic categories with acute physiology scores of 11 or higher were randomly assigned to the three groups (252 to the control group, 253 to the cardiac-index group, and 257 to the oxygen-saturation group). Results The hemodynamic targets were reached by 94.3 percent of the control group, 44.9 percent of the cardiac-index group, and 66.7 percent of the oxygen-saturation group (P<0.001). Mortality was 48.4, ...

1,365 citations

Journal ArticleDOI
TL;DR: Caution is required in elderly patients and anticoagulation intensity should be closely monitored to reduce periods of overdosing and see fewer bleeding events than those recorded in other observational and experimental studies.

1,359 citations

Journal ArticleDOI
TL;DR: In this article, the energy and geometrical features of the interaction are described along with the atomic characteristics that confer molecules with the specific ability to interact through this interaction, and some principles are presented for crystal engineering based on halogen-bonding interactions.
Abstract: Halogen bonding is the noncovalent interaction where halogen atoms function as electrophilic species. The energetic and geometrical features of the interaction are described along with the atomic characteristics that confer molecules with the specific ability to interact through this interaction. Halogen bonding has an impact on all research fields where the control of intermolecular recognition and self-assembly processes plays a key role. Some principles are presented for crystal engineering based on halogen-bonding interactions. The potential of the interaction is also shown by applications in liquid crystals, magnetic and conducting materials, and biological systems.

1,358 citations


Authors

Showing all 58902 results

NameH-indexPapersCitations
Yi Cui2201015199725
Peter J. Barnes1941530166618
Thomas C. Südhof191653118007
Charles A. Dinarello1901058139668
Alberto Mantovani1831397163826
John J.V. McMurray1781389184502
Giuseppe Remuzzi1721226160440
Russel J. Reiter1691646121010
Jean Louis Vincent1611667163721
Tobin J. Marks1591621111604
Tomas Hökfelt158103395979
José Baselga156707122498
Naveed Sattar1551326116368
Silvia Franceschi1551340112504
Frederik Barkhof1541449104982
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023240
2022777
20219,390
20209,000
20197,475
20186,804