Institution
University of Minnesota
Education•Minneapolis, Minnesota, United States•
About: University of Minnesota is a education organization based out in Minneapolis, Minnesota, United States. It is known for research contribution in the topics: Population & Transplantation. The organization has 117432 authors who have published 257986 publications receiving 11944239 citations. The organization is also known as: University of Minnesota, Twin Cities & University of Minnesota-Twin Cities.
Topics: Population, Transplantation, Poison control, Health care, Cancer
Papers published on a yearly basis
Papers
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TL;DR: In this paper, the authors review the performance of the LIGO instruments during this epoch, the work done to characterize the detectors and their data, and the effect that transient and continuous noise artefacts have on the sensitivity of the detectors to a variety of astrophysical sources.
Abstract: In 2009–2010, the Laser Interferometer Gravitational-Wave Observatory (LIGO) operated together with international partners Virgo and GEO600 as a network to search for gravitational waves (GWs) of astrophysical origin. The sensitivity of these detectors was limited by a combination of noise sources inherent to the instrumental design and its environment, often localized in time or frequency, that couple into the GW readout. Here we review the performance of the LIGO instruments during this epoch, the work done to characterize the detectors and their data, and the effect that transient and continuous noise artefacts have on the sensitivity of LIGO to a variety of astrophysical sources.
1,266 citations
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TL;DR: This article examined the relationship between the degree of market orientation from an organizational strategy perspective and organizational processes, individual attitudes and long run financial performance at the business unit level of analysis and found that market orientation varies across business units within large scale organizations and is positively related to broader organizational processes including recruiting, training, and compensation.
1,262 citations
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TL;DR: In this article, the determinants of organizational risk taking and its impact on economic performance are critical issues in strategic management using a model that included risk, performance, performance expecta, and expectation.
Abstract: The determinants of organizational risk taking and its impact on economic performance are critical issues in strategic management. Using a model that included risk, performance, performance expecta...
1,262 citations
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TL;DR: A molecular mechanism linking ULK to the pro-autophagic lipid kinase VPS34 is described, whereby the activated ULK1 phosphorylates Beclin-1 on Ser 14, thereby enhancing the activity of the ATG14L-containing V PS34 complexes.
Abstract: Autophagy is the primary cellular catabolic program activated in response to nutrient starvation. Initiation of autophagy, particularly by amino-acid withdrawal, requires the ULK kinases. Despite its pivotal role in autophagy initiation, little is known about the mechanisms by which ULK promotes autophagy. Here we describe a molecular mechanism linking ULK to the pro-autophagic lipid kinase VPS34. Following amino-acid starvation or mTOR inhibition, the activated ULK1 phosphorylates Beclin-1 on Ser 14, thereby enhancing the activity of the ATG14L-containing VPS34 complexes. The Beclin-1 Ser 14 phosphorylation by ULK is required for full autophagic induction in mammals and this requirement is conserved in Caenorhabditis elegans. Our study reveals a molecular link from ULK1 to activation of the autophagy-specific VPS34 complex and autophagy induction.
1,262 citations
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TL;DR: Among patients with acute decompensated heart failure, there were no significant differences in patients' global assessment of symptoms or in the change in renal function when diuretic therapy was administered by bolus as compared with continuous infusion or at a high dose asCompared with a low dose.
Abstract: Among patients with acute decompensated heart failure, there were no significant differences in patients’ global assessment of symptoms or in the change in renal function when diuretic therapy was administered by bolus as compared with continuous infusion or at a high dose as compared with a low dose. (Funded by the National Heart, Lung, and Blood Institute; ClinicalTrials.gov number, NCT00577135.)
1,261 citations
Authors
Showing all 118112 results
Name | H-index | Papers | Citations |
---|---|---|---|
Walter C. Willett | 334 | 2399 | 413322 |
David J. Hunter | 213 | 1836 | 207050 |
David Miller | 203 | 2573 | 204840 |
Mark I. McCarthy | 200 | 1028 | 187898 |
Dennis W. Dickson | 191 | 1243 | 148488 |
David H. Weinberg | 183 | 700 | 171424 |
Eric Boerwinkle | 183 | 1321 | 170971 |
John C. Morris | 183 | 1441 | 168413 |
Aaron R. Folsom | 181 | 1118 | 134044 |
H. S. Chen | 179 | 2401 | 178529 |
Jie Zhang | 178 | 4857 | 221720 |
Jasvinder A. Singh | 176 | 2382 | 223370 |
Feng Zhang | 172 | 1278 | 181865 |
Gang Chen | 167 | 3372 | 149819 |
Hongfang Liu | 166 | 2356 | 156290 |