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Institution

University of Minnesota

EducationMinneapolis, Minnesota, United States
About: University of Minnesota is a education organization based out in Minneapolis, Minnesota, United States. It is known for research contribution in the topics: Population & Transplantation. The organization has 117432 authors who have published 257986 publications receiving 11944239 citations. The organization is also known as: University of Minnesota, Twin Cities & University of Minnesota-Twin Cities.


Papers
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Journal ArticleDOI
TL;DR: In this paper, the authors determined whether greater carotid artery intima-media thickness (IMT) in asymptomatic individuals is associated with increased risk of coronary heart disease (CHD).
Abstract: Few studies have determined whether greater carotid artery intima-media thickness (IMT) in asymptomatic individuals is associated prospectively with increased risk of coronary heart disease (CHD). In the Atherosclerosis Risk in Communities Study, carotid IMT, an index of generalized atherosclerosis, was defined as the mean of IMT measurements at six sites of the carotid arteries using B-mode ultrasound. The authors assessed its relation to CHD incidence over 4-7 years of follow-up (1987-1993) in four US communities (Forsyth County, North Carolina; Jackson, Mississippi; Minneapolis, Minnesota; and Washington County, Maryland) from samples of 7,289 women and 5,552 men aged 45-64 years who were free of clinical CHD at baseline. There were 96 incident events for women and 194 for men. In sex-specific Cox proportional hazards models adjusted only for age, race, and center, the hazard rate ratio comparing extreme mean IMT (> or = 1 mm) to not extreme (< 1 mm) was 5.07 for women (95% confidence interval 3.08-8.36) and 1.85 for men (95% confidence interval 1.28-2.69). The relation was graded (monotonic), and models with cubic splines indicated significant nonlinearity. The strength of the association was reduced by including major CHD risk factors, but remained elevated at higher IMT. Up to 1 mm mean IMT, women had lower adjusted annual event rates than did men, but above 1 mm their event rate was closer to that of men. Thus, mean carotid IMT is a noninvasive predictor of future CHD incidence.

1,969 citations

Journal ArticleDOI
TL;DR: In this article, the authors quantified the biomass allocation patterns to leaves, stems and roots in vegetative plants, and how this is influenced by the growth environment, plant size, evolutionary history and competition.
Abstract: Contents Summary 30 I. Allocation in perspective 31 II. Topics of this review 32 III. Methodology 32 IV. Environmental effects 33 V. Ontogeny 36 VI. Differences between species 40 VII. Physiology and molecular regulation 41 VIII. Ecological aspects 42 IX. Perspectives 45 Acknowledgements 45 References 45 Appendices A1–A4 49 Summary We quantified the biomass allocation patterns to leaves, stems and roots in vegetative plants, and how this is influenced by the growth environment, plant size, evolutionary history and competition. Dose–response curves of allocation were constructed by means of a meta-analysis from a wide array of experimental data. They show that the fraction of whole-plant mass represented by leaves (LMF) increases most strongly with nutrients and decreases most strongly with light. Correction for size-induced allocation patterns diminishes the LMF-response to light, but makes the effect of temperature on LMF more apparent. There is a clear phylogenetic effect on allocation, as eudicots invest relatively more than monocots in leaves, as do gymnosperms compared with woody angiosperms. Plants grown at high densities show a clear increase in the stem fraction. However, in most comparisons across species groups or environmental factors, the variation in LMF is smaller than the variation in one of the other components of the growth analysis equation: the leaf area : leaf mass ratio (SLA). In competitive situations, the stem mass fraction increases to a smaller extent than the specific stem length (stem length : stem mass). Thus, we conclude that plants generally are less able to adjust allocation than to alter organ morphology.

1,959 citations

01 Jan 1992
TL;DR: In this paper, spectral analysis methods from spectral analysis are used to evaluate numerical accuracy formally and construct diagnostics for convergence in the normal linear model with informative priors, and in the Tobit-censored regression model.
Abstract: Data augmentation and Gibbs sampling are two closely related, sampling-based approaches to the calculation of posterior moments. The fact that each produces a sample whose constituents are neither independent nor identically distributed complicates the assessment of convergence and numerical accuracy of the approximations to the expected value of functions of interest under the posterior. In this paper methods from spectral analysis are used to evaluate numerical accuracy formally and construct diagnostics for convergence. These methods are illustrated in the normal linear model with informative priors, and in the Tobit-censored regression model.

1,955 citations

Journal ArticleDOI
TL;DR: An excess of B-mode power over the base lensed-ΛCDM expectation is found in the range 30 < ℓ < 150, inconsistent with the null hypothesis at a significance of >5σ, and it is shown that systematic contamination is much smaller than the observed excess.
Abstract: We report results from the BICEP2 experiment, a cosmic microwave background (CMB) polarimeter specifically designed to search for the signal of inflationary gravitational waves in the B -mode power spectrum around l∼80 . The telescope comprised a 26 cm aperture all-cold refracting optical system equipped with a focal plane of 512 antenna coupled transition edge sensor 150 GHz bolometers each with temperature sensitivity of ≈300 μK CMB s √ . BICEP2 observed from the South Pole for three seasons from 2010 to 2012. A low-foreground region of sky with an effective area of 380 square deg was observed to a depth of 87 nK deg in Stokes Q and U . In this paper we describe the observations, data reduction, maps, simulations, and results. We find an excess of B -mode power over the base lensed-ΛCDM expectation in the range 30 5σ . Through jackknife tests and simulations based on detailed calibration measurements we show that systematic contamination is much smaller than the observed excess. Cross correlating against WMAP 23 GHz maps we find that Galactic synchrotron makes a negligible contribution to the observed signal. We also examine a number of available models of polarized dust emission and find that at their default parameter values they predict power ∼(5–10)× smaller than the observed excess signal (with no significant cross-correlation with our maps). However, these models are not sufficiently constrained by external public data to exclude the possibility of dust emission bright enough to explain the entire excess signal. Cross correlating BICEP2 against 100 GHz maps from the BICEP1 experiment, the excess signal is confirmed with 3σ significance and its spectral index is found to be consistent with that of the CMB, disfavoring dust at 1.7σ . The observed B -mode power spectrum is well fit by a lensed-ΛCDM+tensor theoretical model with tensor-to-scalar ratio r=0.20 +0.07 −0.05 , with r=0 disfavored at 7.0σ . Accounting for the contribution of foreground, dust will shift this value downward by an amount which will be better constrained with upcoming data sets

1,954 citations

Journal ArticleDOI
27 Jan 1994-Nature
TL;DR: This article showed that primary productivity in more diverse plant communities is more resistant to, and recovers more fully from, a major drought and that each additional species lost from our grasslands had a progressively greater impact on drought resistance.
Abstract: One of the ecological tenets justifying conservation of biodiversity is that diversity begets stability. Impacts of biodiversity on population dynamics and ecosystem functioning have long been debated1–7, however, with many theoretical explorations2–6,8–11 but few field studies12–15. Here we describe a long-term study of grasslands16,17 which shows that primary productivity in more diverse plant communities is more resistant to, and recovers more fully from, a major drought. The curvilinear relationship we observe suggests that each additional species lost from our grasslands had a progressively greater impact on drought resistance. Our results support the diversity—stability hypothesis5,6,18,19, but not the alternative hypothesis that most species are functionally redundant19–21. This study implies that the preservation of biodiversity is essential for the maintenance of stable productivity in ecosystems.

1,941 citations


Authors

Showing all 118112 results

NameH-indexPapersCitations
Walter C. Willett3342399413322
David J. Hunter2131836207050
David Miller2032573204840
Mark I. McCarthy2001028187898
Dennis W. Dickson1911243148488
David H. Weinberg183700171424
Eric Boerwinkle1831321170971
John C. Morris1831441168413
Aaron R. Folsom1811118134044
H. S. Chen1792401178529
Jie Zhang1784857221720
Jasvinder A. Singh1762382223370
Feng Zhang1721278181865
Gang Chen1673372149819
Hongfang Liu1662356156290
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023200
20221,176
202111,903
202011,807
201910,984
201810,367