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Institution

University of Missouri

EducationColumbia, Missouri, United States
About: University of Missouri is a education organization based out in Columbia, Missouri, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 41427 authors who have published 83598 publications receiving 2911437 citations. The organization is also known as: Mizzou & Missouri-Columbia.


Papers
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Journal ArticleDOI
TL;DR: Speleothems are bodies of mineral material formed in caves as the result of chemical precipitation from groundwater flowing or dripping in a cave as discussed by the authors, and they can be found in many locations of the globe, sampled at high-resolution and reliably dated using high-precision uranium series techniques.
Abstract: An increasing number of scientists recognize the value of speleothems1 as often extremely well-preserved archives of information about past climate, vegetation, hydrology, sea level, nuclide migration, water-rock interaction, landscape evolution, tectonics and human action. Well-constrained data are required to document past changes, reconstruct past patterns and predict future responses of the Earth system at a wide range of spatial and temporal scales. Speleothems are particularly useful in this regard because they can be found in many locations of the globe, sampled at high-resolution and reliably dated using high-precision uranium-series techniques. Speleothems are bodies of mineral material formed in caves as the result of chemical precipitation from groundwater flowing or dripping in a cave. Most speleothems are composed of calcite formed by slow degassing of CO2 from supersaturated groundwater, but aragonite and gypsum forms are also common, particularly near cave entrances where evaporative effects are important. A host of different speleothem types decorate the walls, ceilings and floors of caves, and their mineralogy and morphology is a function of fluid flow and chemistry of waters feeding a particular location as well as the ambient conditions (temperature, chemistry, light) in the air or water-filled void. Subaerial forms include the familiar stalagmites, stalactites, draperies, flowstones. Subaqueous forms include rimstone pools, “rafts,” mammillary calcite wall-coatings and “dog-tooth” spar. For an extensive review of the types of speleothem that have been observed, see Hill and Forti (1997). Speleothems are used in a multitude of ways to explore past environmental conditions, perhaps the most fundamental of which is their very presence or absence. Deposition of speleothems relies on sufficient water supply and soil CO2 to enable dissolution and transport of reactants in the vadose zone to underlying caves. In arid or glacial times, conditions may not have been favorable for speleothem formation. …

367 citations

Journal ArticleDOI
TL;DR: In this paper, the critical Rayleigh number was shown to be lower by one to two orders of magnitude than that for regular fluids, emphasizing the combined behaviors of Brownian motion and thermophoresis of nanoparticles.

367 citations

Journal ArticleDOI
TL;DR: Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus by being resistant to the PRRSV isolate NVSL 97-7895, a well-characterized, relatively virulent viral isolate that is commonly used in experimentalPRRSV infection trials.
Abstract: VOLUME 34 NUMBER 1 JANUARY 2016 NATURE BIOTECHNOLOGY To the Editor: Porcine reproductive and respiratory syndrome (PRRS) is the most economically important disease of swine in North America, Europe and Asia, costing producers in North America more than $600 million annually1. The disease syndrome was first recognized in the United States in 1987 and described in 1989 (ref. 2). The causative agent, porcine reproductive and respiratory syndrome virus (PRRSV), was subsequently isolated and characterized in Europe in 1991 (ref. 3). Vaccines have been unable to control the disease. It has been suggested that CD163 is the receptor for entry of PRRSV into cells4. Thus, we hypothesized that pigs with defective CD163 would be immune to PRRSV. Previously we used CRISPRCas9 to generate pigs lacking functional CD163 (ref. 5). Here we demonstrate that these animals are resistant to the PRRSV isolate NVSL 97-7895, a well-characterized, relatively virulent viral isolate that is commonly used in experimental PRRSV infection trials. After infection, they showed no clinical signs (fever or respiratory signs), lung pathology, viremia or antibody response and remained healthy for the 35 d after infection measured in this study. Because CD163 was edited using CRISPR-Cas9, the pigs challenged in this study do not contain any transgenes5. PRRSV is a member of the mammalian arterivirus group, which also includes murine lactate dehydrogenase-elevating virus, simian hemorrhagic fever virus and equine arteritis virus. The arteriviruses share important pathogenesis properties, including macrophage tropism and the capacity to cause both severe disease and persistent infection. In young pigs, infection with PRRSV results in respiratory disease, including cough and fever and reduced growth performance. In pregnant sows, PRRSV infection can result in reproductive failure, as well as persistently infected and low birth weight piglets.The virus is associated with polymicrobial disease syndromes, including porcine respiratory Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus

367 citations

Journal ArticleDOI
TL;DR: For instance, this paper found that playing the video game Tetris improves mental rotation time and spatial visualization time in older adolescents. But none of the subjects had any prior experience with Tetris, a video game requiring the rapid rotation and placement of seven different-shaped blocks, and the results indicated that reliable and consistent differences between males and females were only obtained on complex mental rotation tasks.

367 citations

Journal ArticleDOI
20 Sep 2019-Science
TL;DR: In this paper, the authors used photoemission spectroscopy and quantum transport to elucidate the topology of the room temperature magnet Co2MnGa and observed sharp bulk Weyl fermion line dispersions indicative of nontrivial topological invariants present in the magnetic phase.
Abstract: Topological matter is known to exhibit unconventional surface states and anomalous transport owing to unusual bulk electronic topology. In this study, we use photoemission spectroscopy and quantum transport to elucidate the topology of the room temperature magnet Co2MnGa. We observe sharp bulk Weyl fermion line dispersions indicative of nontrivial topological invariants present in the magnetic phase. On the surface of the magnet, we observe electronic wave functions that take the form of drumheads, enabling us to directly visualize the crucial components of the bulk-boundary topological correspondence. By considering the Berry curvature field associated with the observed topological Weyl fermion lines, we quantitatively account for the giant anomalous Hall response observed in this magnet. Our experimental results suggest a rich interplay of strongly interacting electrons and topology in quantum matter.

366 citations


Authors

Showing all 41750 results

NameH-indexPapersCitations
Walter C. Willett3342399413322
Meir J. Stampfer2771414283776
Russel J. Reiter1691646121010
Chad A. Mirkin1641078134254
Robert Stone1601756167901
Howard I. Scher151944101737
Rajesh Kumar1494439140830
Joseph T. Hupp14173182647
Lihong V. Wang136111872482
Stephen R. Carpenter131464109624
Jan A. Staessen130113790057
Robert S. Brown130124365822
Mauro Giavalisco12841269967
Kenneth J. Pienta12767164531
Matthew W. Gillman12652955835
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023120
2022532
20213,697
20203,683
20193,339
20183,182