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Institution

University of Missouri

EducationColumbia, Missouri, United States
About: University of Missouri is a education organization based out in Columbia, Missouri, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 41427 authors who have published 83598 publications receiving 2911437 citations. The organization is also known as: Mizzou & Missouri-Columbia.


Papers
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Journal ArticleDOI
TL;DR: This paper found that attachment anxiety was negatively associated with students' acculturation to U.S. culture, and that attachment avoidance, attachment anxiety, and attachment avoidance were significant predictors for students' psychosocial adjustment.
Abstract: On the basis of a process model of acculturation (Berry, Kim, Minde, & Mok, 1987) and the concept of secure base for interpersonal exploration in adult attachment (Bowlby, 1988), this study hypothesized that sociocultural adjustment difficulties and psychological distress of Chinese international students (N = 104) living in the United States would be positively associated with attachment avoidance and anxiety and negatively associated with both acculturation to the U.S. culture and identification with the home culture. Survey packets contained the Experiences in Close Relationships scale, the Acculturation Index, the Socio-Cultural Adaptation Scale, and the Brief Symptom Inventory-18. Results suggested that attachment anxiety was negatively associated with students' acculturation to U.S. culture, and that attachment avoidance, attachment anxiety, and acculturation to U.S. culture were significant predictors for students' psychosocial adjustment.

349 citations

Journal ArticleDOI
TL;DR: The studies with animal models have provided information clearly indicating the ability of grape polyphenols to ameliorate neuronal damages due to chronic ethanol consumption, and the need to extend research beyond the "French Paradox" towards better understanding molecular mechanisms of action of polyphenolic compounds and their application to human health.

348 citations

Journal ArticleDOI
TL;DR: In this paper, the mesoporous surfaces of TMOS-derived silica aerogels have been modified with amines by copolymerization with APTES, and the amine sites have become anchors for cross-linking the nanoparticles of the skeletal backbone of the aerogel by attachment of di-, tri-, and tetra functional epoxies.
Abstract: The mesoporous surfaces of TMOS-derived silica aerogels have been modified with amines by copolymerization of TMOS with APTES. The amine sites have become anchors for cross-linking the nanoparticles of the skeletal backbone of the aerogel by attachment of di-, tri-, and tetra-functional epoxies. The resulting conformal coatings increase the density of the native aerogels by a factor of 2−3 but the strength of the resulting materials may increase by more than 2 orders of magnitude. Processing variables such as the amount of APTES used to make the gels, the epoxy type and concentration used for cross-linking, and the cross-linking temperature and time were varied according to a multivariable design-of-experiments (DOE) model. It was found that while elastic modulus follows a similar trend with density, maximum strength is attained neither at the maximum density nor at the highest concentration of −NH2 groups, suggesting surface saturation effects. Aerogels cross-linked with the trifunctional epoxide always ...

348 citations

Journal ArticleDOI
TL;DR: The increased release of citrate may provide a mechanism by which P-stressed plants enhance the availability of P in the rhizosphere.
Abstract: Under certain stress conditions roots exude organic molecules, which may facilitate the uptake of nutrients. The objective of this research was to identify and measure the effect of low P upon the exudation of organic acids by roots of alfalfa (Medicago sativa L.) seedlings. Surface-sterilized alfalfa seeds were grown aseptically in sterile sand using an apparatus specially designed for the addition of ±P nutrient solutions and for the collection of root exudates. Citric, malic, and succinic acids were detected in the root exudates of 24-day-old alfalfa seedlings. Citrate exudation from the roots of P-stressed alfalfa was 182% that of plants receiving a complete nutrient solution. The increased release of citrate may provide a mechanism by which P-stressed plants enhance the availability of P in the rhizosphere.

348 citations

Journal ArticleDOI
TL;DR: Evidence is emerging that mineralocorticoid receptor blockade is useful in treating hypertensive patients who have both the metabolic syndrome and resistant hypertension, and evidence shows that elevated plasma aldosterone levels directly contribute to the pathogenesis of insulin resistance and endothelial dysfunction.
Abstract: The prevalence of obesity, diabetes, hypertension, and cardiovascular and chronic kidney disease is increasing in developed countries. Obesity, insulin resistance, and hypertension commonly cluster with other risk factors for cardiovascular and chronic kidney disease to form the metabolic syndrome. Emerging evidence supports a paradigm shift in our understanding of the renin-angiotensin-aldosterone system and in aldosterone's ability to promote insulin resistance and participate in the pathogenesis of the metabolic syndrome and resistant hypertension. Recent data suggest that excess circulating aldosterone promotes the development of both disorders by impairing insulin metabolic signaling and endothelial function, which in turn leads to insulin resistance and cardiovascular and renal structural and functional abnormalities. Indeed, hyperaldosteronism is associated with impaired pancreatic beta-cell function, skeletal muscle insulin sensitivity, and elevated production of proinflammatory adipokines from adipose tissue, which results in systemic inflammation and impaired glucose tolerance. Accumulating evidence indicates that the cardiovascular and renal abnormalities associated with insulin resistance are mediated in part by aldosterone acting on the mineralocorticoid receptor. Although we have known that mineralocorticoid receptor blockade attenuates cardiovascular and renal injury, only recently have we learned that mineralocorticoid receptor blockade improves pancreatic insulin release, insulin-mediated glucose utilization, and endothelium-dependent vasorelaxation. In summary, aldosterone excess has detrimental metabolic effects that contribute to the metabolic syndrome and endothelial dysfunction, which in turn contribute to the development of resistant hypertension as well as cardiovascular disease and chronic kidney disease.

348 citations


Authors

Showing all 41750 results

NameH-indexPapersCitations
Walter C. Willett3342399413322
Meir J. Stampfer2771414283776
Russel J. Reiter1691646121010
Chad A. Mirkin1641078134254
Robert Stone1601756167901
Howard I. Scher151944101737
Rajesh Kumar1494439140830
Joseph T. Hupp14173182647
Lihong V. Wang136111872482
Stephen R. Carpenter131464109624
Jan A. Staessen130113790057
Robert S. Brown130124365822
Mauro Giavalisco12841269967
Kenneth J. Pienta12767164531
Matthew W. Gillman12652955835
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023120
2022532
20213,697
20203,683
20193,339
20183,182