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Institution

University of Missouri

EducationColumbia, Missouri, United States
About: University of Missouri is a education organization based out in Columbia, Missouri, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 41427 authors who have published 83598 publications receiving 2911437 citations. The organization is also known as: Mizzou & Missouri-Columbia.


Papers
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Journal ArticleDOI
04 Dec 1997-Nature
TL;DR: It is shown that oestrogen regulates the reabsorption of luminal fluid in the head of the epididymis, which raises further concern over the potential direct effects of environmental oestrogens on male reproduction and reported declines in human sperm counts.
Abstract: Oestrogen is considered to be the 'female' hormone, whereas testosterone is considered the 'male' hormone. However, both hormones are present in both sexes. Thus sexual distinctions are not qualitative differences, but rather result from quantitative divergence in hormone concentrations and differential expressions of steroid hormone receptors. In males, oestrogen is present in low concentrations in blood, but can be extraordinarily high in semen, and as high as 250 pg ml(-1) in rete testis fluids, which is higher than serum oestradiol in the female. It is well known that male reproductive tissues express oestrogen receptors, but the role of oestrogen in male reproduction has remained unclear. Here we provide evidence of a physiological role for oestrogen in male reproductive organs. We show that oestrogen regulates the reabsorption of luminal fluid in the head of the epididymis. Disruption of this essential function causes sperm to enter the epididymis diluted, rather than concentrated, resulting in infertility. This finding raises further concern over the potential direct effects of environmental oestrogens on male reproduction and reported declines in human sperm counts.

854 citations

Journal ArticleDOI
TL;DR: Current and future trends in usage, together with the many benefits that plastics bring to society are described, along with the environmental consequences resulting from the accumulation of waste plastic and the effects of plastic debris on wildlife.
Abstract: Within the last few decades, plastics have revolutionized our daily lives. Globally we use in excess of 260 million tonnes of plastic per annum, accounting for approximately 8 per cent of world oil production. In this Theme Issue of Philosophical Transactions of the Royal Society, we describe current and future trends in usage, together with the many benefits that plastics bring to society. At the same time, we examine the environmental consequences resulting from the accumulation of waste plastic, the effects of plastic debris on wildlife and concerns for human health that arise from the production, usage and disposal of plastics. Finally, we consider some possible solutions to these problems together with the research and policy priorities necessary for their implementation.

853 citations

Journal ArticleDOI
TL;DR: A sensor network can provide access to information anytime, anywhere by collecting, processing, analyzing and disseminating data, and actively participates in creating a smart environment.
Abstract: Advances in hardware and wireless network technologies have created low-cost, low-power, multifunctional miniature sensor devices. These devices make up hundreds or thousands of ad hoc tiny sensor nodes spread across a geographical area. These sensor nodes collaborate among themselves to establish a sensing network. A sensor network can provide access to information anytime, anywhere by collecting, processing, analyzing and disseminating data. Thus, the network actively participates in creating a smart environment.

851 citations

Journal ArticleDOI
TL;DR: It may be time to consider a shift to a dimensional classification of personality disorder that would help address the failures of the existing diagnostic categories as well as contribute to an integration of the psychiatric diagnostic manual with psychology's research on general personality structure.
Abstract: The diagnostic categories of the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders were developed in the spirit of a traditional medical model that considers mental disorders to be qualitatively distinct conditions (see, e.g., American Psychiatric Association, 2000). Work is now beginning on the fifth edition of this influential diagnostic manual. It is perhaps time to consider a fundamental shift in how psychopathology is conceptualized and diagnosed. More specifically, it may be time to consider a shift to a dimensional classification of personality disorder that would help address the failures of the existing diagnostic categories as well as contribute to an integration of the psychiatric diagnostic manual with psychology's research on general personality structure.

849 citations

Journal ArticleDOI
TL;DR: In this article, the authors examined the relationship between governance and corporate innovation strategies, and found that differences among governance constitue a barrier between innovation and corporate success, in opposition to the assumption that owners have a unified voice.
Abstract: Examining the relationship between governance and corporate innovation strategies, we found, in opposition to the assumption that owners have a unified voice, differences among governance constitue

848 citations


Authors

Showing all 41750 results

NameH-indexPapersCitations
Walter C. Willett3342399413322
Meir J. Stampfer2771414283776
Russel J. Reiter1691646121010
Chad A. Mirkin1641078134254
Robert Stone1601756167901
Howard I. Scher151944101737
Rajesh Kumar1494439140830
Joseph T. Hupp14173182647
Lihong V. Wang136111872482
Stephen R. Carpenter131464109624
Jan A. Staessen130113790057
Robert S. Brown130124365822
Mauro Giavalisco12841269967
Kenneth J. Pienta12767164531
Matthew W. Gillman12652955835
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023120
2022532
20213,697
20203,683
20193,339
20183,182