scispace - formally typeset
Search or ask a question
Institution

University of Missouri

EducationColumbia, Missouri, United States
About: University of Missouri is a education organization based out in Columbia, Missouri, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 41427 authors who have published 83598 publications receiving 2911437 citations. The organization is also known as: Mizzou & Missouri-Columbia.


Papers
More filters
Journal ArticleDOI
01 Jun 1998
TL;DR: Molecular investigations of boron nutrition have been initiated by the discovery of a novel mutant of Arabidopsis thaliana with an altered requirement for borOn, which has been implicated in counteracting toxic effects of aluminum on root growth of dicotyledonous plants.
Abstract: ▪ Abstract New and exciting developments in boron research in the past few years greatly contributed to better understanding of the role of boron in plants. Purification and identification of the first boron-polyol transport molecules resolved much of the controversy about boron phloem mobility. Isolation and characterization of the boron-polysaccharide complex from cell walls provided the first direct evidence for boron crosslinking of pectin polymers. Inhibition and recovery of proton release upon boron withdrawal and restitution in plant culture medium demonstrated boron involvement in membrane processes. Rapid boron-induced changes in membrane function could be attributed to boron-complexing membrane constituents. Boron may affect metabolic pathways by binding apoplastic proteins to cis-hydroxyl groups of cell walls and membranes, and by interfering with manganese-dependent enzymatic reactions. In addition, boron has been implicated in counteracting toxic effects of aluminum on root growth of dicotyle...

737 citations

Journal ArticleDOI
TL;DR: In this article, the authors introduce the concept of netchain analysis, which is a set of networks comprised of horizontal ties between firms within a particular industry or group, which are sequentially arranged based on vertical ties among firms in different layers.
Abstract: This paper introduces the concept of netchain analysis. A netchain is a set of networks comprised of horizontal ties between firms within a particular industry or group, which are sequentially arranged based on vertical ties between firms in different layers. Netchain analysis interprets supply chain and network perspectives on inter-organisational collaboration with particular emphasis on the value creating and coordination mechanism sources. We posit that sources of value and coordination mechanisms correspond to particular and distinct types of interdependencies: pooled, sequential, and reciprocal. It is further argued that the recognition and accounting of these simultaneous interdependencies is crucial for a more advanced understanding of complex inter-organisational relations. The paper concludes with an analysis of a set of netchain configuration examples, including buyer-supplier relationships, information technology induced interorganization collaborations, and the introduction of the "macrohiera...

736 citations

Journal ArticleDOI
Yang Liu1, Lili He1, Azlin Mustapha1, Hao Li1, Zhiqiang Hu1, Mengshi Lin1 
TL;DR: To investigate antibacterial activities of zinc oxide nanoparticles (ZnO NP) and their mode of action against an important foodborne pathogen, Escherichia coli O157:H7.
Abstract: Aims: To investigate antibacterial activities of zinc oxide nanoparticles (ZnO NP) and their mode of action against an important foodborne pathogen, Escherichia coli O157:H7. Methods and Results: ZnO NP with sizes of 70 nm and concentrations of 0, 3, 6 and 12 mmol l−1 and NP-free solutions were used in antimicrobial tests against E. coli O157:H7. ZnO NP showed increasing inhibitory effects on the growth of E. coli O157:H7 as the concentrations of ZnO NP increased. A complete inhibition of microbial growth was achieved at the concentration level of 12 mmol l−1 or higher. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Raman spectroscopy were used to characterize the changes of morphology and cellular compositions of bacterial cells treated with ZnO NP and study the mode of action of ZnO NP against E. coli O157:H7. The intensity of lipid and protein bands in the Raman spectra of bacterial cells increased after exposure to ZnO NP, while no significant changes in nucleic acid bands were observed. Conclusions: ZnO NP were found to have antibacterial activity against E. coli O157:H7. The inhibitory effects increase as the concentration of ZnO NP increased. Results indicate that ZnO NP may distort and damage bacterial cell membrane, resulting in a leakage of intracellular contents and eventually the death of bacterial cells. Significance and Impact of the Study: These results suggest that ZnO NP could potentially be used as an effective antibacterial agent to protect agricultural and food safety.

735 citations

Journal ArticleDOI
26 Sep 2008-Science
TL;DR: The pig model may provide opportunities to address persistent questions about CF pathogenesis and accelerate discovery of strategies for prevention and treatment.
Abstract: Almost two decades after CFTR was identified as the gene responsible for cystic fibrosis (CF), we still lack answers to many questions about the pathogenesis of the disease, and it remains incurable. Mice with a disrupted CFTR gene have greatly facilitated CF studies, but the mutant mice do not develop the characteristic manifestations of human CF, including abnormalities of the pancreas, lung, intestine, liver, and other organs. Because pigs share many anatomical and physiological features with humans, we generated pigs with a targeted disruption of both CFTR alleles. Newborn pigs lacking CFTR exhibited defective chloride transport and developed meconium ileus, exocrine pancreatic destruction, and focal biliary cirrhosis, replicating abnormalities seen in newborn humans with CF. The pig model may provide opportunities to address persistent questions about CF pathogenesis and accelerate discovery of strategies for prevention and treatment.

735 citations

Journal ArticleDOI
TL;DR: In this article, the authors examined the effect of delinquent lifestyles on the criminal victimization of teenagers and young adults and found that adolescent involvement in delinquent lifestyles strongly increases the risk of both personal and property victimization.
Abstract: Prior research on victimization in the United States has generally neglected two key areas—victimization among juveniles and young adults and the connection between offending and victimization. The research presented here fuses these two concerns by examining the effect of delinquent lifestyles on the criminal victimization of teenagers and young adults. An examination of longitudinal data from the first five waves of the National Youth Survey suggests that adolescent involvement in delinquent lifestyles strongly increases the risk of both personal and property victimization. Further, the analysis reveals that a significant proportion of the risk of victimization incurred by different demographic subgroups—especially males—results from greater involvement in lifestyles characterized by delinquency. The authors conclude that victimization patterns among youths cannot be understood apart from criminal and deviant activities.

734 citations


Authors

Showing all 41750 results

NameH-indexPapersCitations
Walter C. Willett3342399413322
Meir J. Stampfer2771414283776
Russel J. Reiter1691646121010
Chad A. Mirkin1641078134254
Robert Stone1601756167901
Howard I. Scher151944101737
Rajesh Kumar1494439140830
Joseph T. Hupp14173182647
Lihong V. Wang136111872482
Stephen R. Carpenter131464109624
Jan A. Staessen130113790057
Robert S. Brown130124365822
Mauro Giavalisco12841269967
Kenneth J. Pienta12767164531
Matthew W. Gillman12652955835
Network Information
Related Institutions (5)
University of Wisconsin-Madison
237.5K papers, 11.8M citations

97% related

University of Minnesota
257.9K papers, 11.9M citations

97% related

Cornell University
235.5K papers, 12.2M citations

97% related

Ohio State University
222.7K papers, 8.3M citations

96% related

University of Illinois at Urbana–Champaign
225.1K papers, 10.1M citations

95% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023120
2022532
20213,697
20203,683
20193,339
20183,182