Showing papers by "University of Modena and Reggio Emilia published in 1979"
Journal Article•
TL;DR: Therapeutically, confirmation was obtained of the effectiveness, at least temporarily, of corticosteroid treatment and antilymphocyte globulin was experimented for the first time in these patients and might be used to replace the immune depressant antiblastic substances already successfully employed in patients with Behcet's disease.
Abstract: 6 cases of Behcet's disease are reported. Diagnosis was particularly arduous because the typical triad of symptoms (oral aphthae, genital ulcers, uveitis) was masked by secondary disturbances in other organs and systems. Immunology confirmed the presence in these patients of changes in various in vivo and in vitro tests and particularly interesting was the aspecific cutaneous hypersensitivity seen in 5 cases and enhanced lymphocyte blastic transformation. This was seen spontaneously and following PHA. On the basis of the outcome of the studies carried out and the literature data, the possibility that Behcet's disease may contain immunological changes and changes in the mechanisms that regulate quinine, complement and clotting activation is suggested. Therapeutically, confirmation was obtained of the effectiveness, at least temporarily, of corticosteroid treatment and antilymphocyte globulin was experimented for the first time in these patients. This might be used to replace the immune depressant antiblastic substances already successfully employed in patients with Behcet's disease.
3 citations
TL;DR: A case of simultaneous penetrating gunshot wounds of the myocardium and thoracic aorta when the patient survived more than 30 minutes and was successfully treated surgically.
Abstract: The frequency of trauma and penetrating wounds of the heart and the great intrathoracic vessels is continuously increasing. In peacetime heart wounds constitute about 3% of all penetrating wounds of the chest. About 40% of patients with penetrating wounds of the heart reach hospital alive. If these patients undergo an immediate pericardiocentesis and operation they have an 80-90% chance of survival. In a study of cases of penetrating gunshot wounds of the heart and aorta 31 patients died immediately while five survived for at least 30 minutes (Parmley et al, 1958). We present a case of simultaneous penetrating gunshot wounds of the myocardium and thoracic aorta when the patient survived more than 30 minutes and was successfully treated surgically. Repeated assessment during the four years since the injury has not shown any late complications.
2 citations