Institution
University of Modena and Reggio Emilia
Education•Modena, Italy•
About: University of Modena and Reggio Emilia is a education organization based out in Modena, Italy. It is known for research contribution in the topics: Population & Transplantation. The organization has 8179 authors who have published 22418 publications receiving 671337 citations. The organization is also known as: Università degli Studi di Modena e Reggio Emilia & Universita degli Studi di Modena e Reggio Emilia.
Topics: Population, Transplantation, Stem cell, Cancer, Breast cancer
Papers published on a yearly basis
Papers
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TL;DR: In patients with previously untreated multiple myeloma, long-term outcome with respect to progression-free survival, overall survival, and relapse rate is superior after auto-allo compared with auto only, and nonrelapse mortality is at a reasonable level in both groups.
Abstract: Purpose Results of allogeneic stem-cell transplantation (allo) in myeloma are controversial. In this trial autologous stem-cell transplantation (auto) followed by reduced-intensity conditioning matched sibling donor allo (auto-allo) was compared with auto only in previously untreated multiple myeloma. Patients and Methods In all, 357 patients with myeloma up to age 69 years were enrolled from 2001 to 2005. Patients with an HLA-identical sibling donor were allocated to the auto-allo arm (n = 108) and patients without a matched sibling donor were allocated to the auto arm (n = 249). Single (n = 145) or tandem (n = 104) auto was optional. Conditioning for the auto arm was melphalan 200 mg/m2; conditioning for the allo arm was total-body irradiation 2 Gy plus fludarabine 30 mg/m2/d for 3 days. Median follow-up time was 61 months. Primary end point was progression-free survival. Results Progression-free survival at 60 months was significantly better with auto-allo than with allo alone (35% v 18%; P = .001), as...
166 citations
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11 Jun 2017TL;DR: A novel intrusion detection algorithm that aims to identify malicious CAN messages injected by attackers in the CAN bus of modern vehicles is proposed, characterized by small memory and computational footprints, that make it applicable to current ECUs.
Abstract: This paper proposes a novel intrusion detection algorithm that aims to identify malicious CAN messages injected by attackers in the CAN bus of modern vehicles. The proposed algorithm identifies anomalies in the sequence of messages that flow in the CAN bus and is characterized by small memory and computational footprints, that make it applicable to current ECUs. Its detection performance are demonstrated through experiments carried out on real CAN traffic gathered from an unmodified licensed vehicle.
166 citations
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King's College London1, Guy's and St Thomas' NHS Foundation Trust2, University of Göttingen3, Charité4, Claude Bernard University Lyon 15, Radboud University Nijmegen6, Pasteur Institute7, University Hospital Heidelberg8, University of Duisburg-Essen9, University of Amsterdam10, University of Valladolid11, Carlos III Health Institute12, University of Barcelona13, National and Kapodistrian University of Athens14, University of Modena and Reggio Emilia15, University of Medicine and Pharmacy of Craiova16, University of Bonn17, University of Bern18
TL;DR: The role of key immune cells, the cause of lymphopenia, organ-specific immunology, the dynamics of sepsis-associated immunological alterations, the role of the microbiome, the standardisation of immunological tests, the development of better animal models, and the opportunities offered by immunotherapy are discussed.
Abstract: Increasing evidence supports a central role of the immune system in sepsis, but the current view of how sepsis affects immunity, and vice versa, is still rudimentary. The European Group on Immunology of Sepsis has identified major gaps that should be addressed with high priority, such as understanding how immunological alterations predispose to sepsis, key aspects of the immunopathological events during sepsis, and the long-term consequences of sepsis on patient's immunity. We discuss major unmet topics in those three categories, including the role of key immune cells, the cause of lymphopenia, organ-specific immunology, the dynamics of sepsis-associated immunological alterations, the role of the microbiome, the standardisation of immunological tests, the development of better animal models, and the opportunities offered by immunotherapy. Addressing these gaps should help us to better understand sepsis physiopathology, offering translational opportunities to improve its prevention, diagnosis, and care.
165 citations
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TL;DR: The aim is to take a correct view of the available stem cell subtypes and their rational use in the medical area, with a specific focus on their therapeutic benefits and side effects.
Abstract: Stem cells are a relevant source of information about cellular differentiation, molecular processes and tissue homeostasis, but also one of the most putative biological tools to treat degenerative diseases. This review focuses on human stem cells clinical and experimental applications. Our aim is to take a correct view of the available stem cell subtypes and their rational use in the medical area, with a specific focus on their therapeutic benefits and side effects. We have reviewed the main clinical trials dividing them basing on their clinical applications, and taking into account the ethical issue associated with the stem cell therapy.
164 citations
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TL;DR: Reflectance difference spectroscopy in combination with ab initio calculations show that ultranarrow graphene nanoribbons have fully anisotropic optical properties dominated by excitonic effects that sensitively depend on the exact atomic structure.
Abstract: Graphene nanoribbons exhibit an electronic bandgap and optical response that can be tuned with the ribbon width. Here, using reflectance difference spectroscopy, Denk et al. investigate the exciton-dominated optical absorption of graphene nanoribbons and its dependence on the exact atomic structure.
164 citations
Authors
Showing all 8322 results
Name | H-index | Papers | Citations |
---|---|---|---|
Carlo M. Croce | 198 | 1135 | 189007 |
Gregory Y.H. Lip | 169 | 3159 | 171742 |
Geoffrey Burnstock | 141 | 1488 | 99525 |
Peter M. Rothwell | 134 | 779 | 67382 |
Claudio Franceschi | 120 | 856 | 59868 |
Lorenzo Galluzzi | 118 | 477 | 71436 |
Leonardo M. Fabbri | 109 | 566 | 60838 |
David N. Reinhoudt | 107 | 1082 | 48814 |
Stefano Pileri | 100 | 635 | 43369 |
Andrea Bizzeti | 99 | 1168 | 46880 |
Brian K. Shoichet | 98 | 281 | 40313 |
Dante Gatteschi | 97 | 727 | 48729 |
Roberta Sessoli | 95 | 424 | 41458 |
Thomas A. Buchholz | 93 | 494 | 33409 |
Pier Luigi Zinzani | 92 | 857 | 35476 |