scispace - formally typeset
Search or ask a question
Institution

University of Münster

EducationMünster, Germany
About: University of Münster is a education organization based out in Münster, Germany. It is known for research contribution in the topics: Population & Transplantation. The organization has 35609 authors who have published 69059 publications receiving 2278534 citations. The organization is also known as: University of Munster & University of Muenster.


Papers
More filters
Journal ArticleDOI
TL;DR: The goal of the present paper is to contribute to the effective documentation and communication of advances by providing updated guidelines for conducting and reporting EEG/MEG studies, which include a checklist of key information recommended for inclusion in research reports on EEG/ MEG measures.
Abstract: Electromagnetic data collected using electroencephalography (EEG) and magnetoencephalography (MEG) are of central importance for psychophysiological research. The scope of concepts, methods, and instruments used by EEG/MEG researchers has dramatically increased and is expected to further increase in the future. Building on existing guideline publications, the goal of the present paper is to contribute to the effective documentation and communication of such advances by providing updated guidelines for conducting and reporting EEG/MEG studies. The guidelines also include a checklist of key information recommended for inclusion in research reports on EEG/MEG measures.

485 citations

Journal ArticleDOI
TL;DR: It is shown that chromoplasts in the tomato fruit express the transgene to ∼50% of the expression levels in leaf chloroplasts, which paves the way to efficient production of edible vaccines, pharmaceuticals, and antibodies in tomato.
Abstract: Transgenic chloroplasts offer unique advantages in plant biotechnology, including high-level foreign protein expression, absence of epigenetic effects, and gene containment due to the lack of transgene transmission through pollen. However, broad application of plastid genome engineering in biotechnology has been largely hampered by both the lack of chloroplast transformation systems for major crop plants and the usually low plastid gene expression levels in nongreen tissues such as fruits, tubers, and other storage organs. Here we describe the development of a plastid transformation system for tomato, Lycopersicon esculentum. This is the first report on the generation of fertile transplastomic plants in a food crop with an edible fruit. We show that chromoplasts in the tomato fruit express the transgene to ∼50% of the expression levels in leaf chloroplasts. Given the generally very high foreign protein accumulation rates that can be achieved in transgenic chloroplasts (>40% of the total soluble protein), this system paves the way to efficient production of edible vaccines, pharmaceuticals, and antibodies in tomato.

485 citations

Journal ArticleDOI
A. V. Witte1, Manfred Fobker1, R. Gellner1, Stefan Knecht1, Agnes Flöel1 
TL;DR: Beneficial effects of caloric restriction on memory performance in healthy elderly subjects are demonstrated and might include higher synaptic plasticity and stimulation of neurofacilitatory pathways in the brain because of improved insulin sensitivity and reduced inflammatory activity.
Abstract: Animal studies suggest that diets low in calories and rich in unsaturated fatty acids (UFA) are beneficial for cognitive function in age. Here, we tested in a prospective interventional design whether the same effects can be induced in humans. Fifty healthy, normal- to overweight elderly subjects (29 females, mean age 60.5 years, mean body mass index 28 kg/m(2)) were stratified into 3 groups: (i) caloric restriction (30% reduction), (ii) relative increased intake of UFAs (20% increase, unchanged total fat), and (iii) control. Before and after 3 months of intervention, memory performance was assessed under standardized conditions. We found a significant increase in verbal memory scores after caloric restriction (mean increase 20%; P < 0.001), which was correlated with decreases in fasting plasma levels of insulin and high sensitive C-reactive protein, most pronounced in subjects with best adherence to the diet (all r values < -0.8; all P values <0.05). Levels of brain-derived neurotrophic factor remained unchanged. No significant memory changes were observed in the other 2 groups. This interventional trial demonstrates beneficial effects of caloric restriction on memory performance in healthy elderly subjects. Mechanisms underlying this improvement might include higher synaptic plasticity and stimulation of neurofacilitatory pathways in the brain because of improved insulin sensitivity and reduced inflammatory activity. Our study may help to generate novel prevention strategies to maintain cognitive functions into old age.

485 citations

Journal ArticleDOI
Betty Abelev1, Jaroslav Adam2, Dagmar Adamová3, Andrew Marshall Adare4  +1002 moreInstitutions (89)
04 Mar 2013
TL;DR: In this paper, the authors measured the transverse-momentum (p(T)) distributions and yields of pi, K, and p in Pb-Pb collisions at root s(NN) = 2.76 TeV.
Abstract: In this paper measurements are presented of pi(+/-), K-+/-, p, and (p) over bar production at midrapidity (vertical bar y vertical bar < 0.5), in Pb-Pb collisions at root s(NN) = 2.76 TeV as a function of centrality. The measurement covers the transverse-momentum (p(T)) range from 100, 200, and 300 MeV/c up to 3, 3, and 4.6 GeV/c for pi, K, and p, respectively. The measured p(T) distributions and yields are compared to expectations based on hydrodynamic, thermal and recombination models. The spectral shapes of central collisions show a stronger radial flow than measured at lower energies, which can be described in hydrodynamic models. In peripheral collisions, the p(T) distributions are not well reproduced by hydrodynamic models. Ratios of integrated particle yields are found to be nearly independent of centrality. The yield of protons normalized to pions is a factor similar to 1.5 lower than the expectation from thermal models.

485 citations

Journal ArticleDOI
S. S. Adler1, S. Afanasiev2, Christine Angela Aidala1, N. N. Ajitanand3  +337 moreInstitutions (40)
TL;DR: In this paper, the authors measured the transverse momentum spectra of neutral pions in the range 1 < p_T < 10 GeV/c and showed that the pi^0 multiplicity in central reactions is significantly below the yields measured at the same squarert(s_NN) in peripheral Au+Au and p+p reactions scaled by the number of nucleon-nucleon collisions.
Abstract: Transverse momentum spectra of neutral pions in the range 1 < p_T < 10 GeV/c have been measured at mid-rapidity by the PHENIX experiment at RHIC in Au+Au collisions at sqrt(s_NN) = 200 GeV. The pi^0 multiplicity in central reactions is significantly below the yields measured at the same sqrt(s_NN) in peripheral Au+Au and p+p reactions scaled by the number of nucleon-nucleon collisions. For the most central bin, the suppression factor is ~2.5 at p_T = 2 GeV/c and increases to ~4-5 at p_T ~= 4 GeV/c. At larger p_T, the suppression remains constant within errors. The deficit is already apparent in semi-peripheral reactions and increases smoothly with centrality.

485 citations


Authors

Showing all 36075 results

NameH-indexPapersCitations
Hyun-Chul Kim1764076183227
Klaus Müllen1642125140748
Giacomo Bruno1581687124368
Anders M. Dale156823133891
Holger J. Schünemann141810113169
Joachim Heinrich136130976887
Markus Merschmeyer132118884975
Klaus Ley12949557964
Robert W. Mahley12836360774
Robert J. Kurman12739760277
Bart Barlogie12677957803
Thomas Schwarz12370154560
Carlos Caldas12254773840
Klaus Weber12152460346
Andrey L. Rogach11757646820
Network Information
Related Institutions (5)
Ludwig Maximilian University of Munich
161.5K papers, 5.7M citations

96% related

University of Zurich
124K papers, 5.3M citations

96% related

University of Amsterdam
140.8K papers, 5.9M citations

95% related

University of Pittsburgh
201K papers, 9.6M citations

95% related

University of California, Irvine
113.6K papers, 5.5M citations

95% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023253
2022831
20213,683
20203,499
20193,236
20182,918