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Institution

University of Naples Federico II

EducationNaples, Campania, Italy
About: University of Naples Federico II is a education organization based out in Naples, Campania, Italy. It is known for research contribution in the topics: Population & Cancer. The organization has 29291 authors who have published 68803 publications receiving 1920149 citations. The organization is also known as: Università degli Studi di Napoli Federico II & Naples University.


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Journal ArticleDOI
Paolo Caraceni1, Oliviero Riggio2, Paolo Angeli3, Carlo Alessandria4, Sergio Neri5, Francesco Giuseppe Foschi, F. Levantesi6, Aldo Airoldi, S. Boccia, Gianluca Svegliati-Baroni, Stefano Fagiuoli, Roberto Giulio Romanelli7, Raffaele Cozzolongo, Vito Di Marco8, Vincenzo Sangiovanni, Filomena Morisco9, Pierluigi Toniutto10, Annalisa Tortora11, Rosanna De Marco, Mario Angelico12, Irene Cacciola, Gianfranco Elia, Alessandro Federico13, Sara Massironi, Riccardo Guarisco, Alessandra Galioto, Giorgio Ballardini6, Maria Rendina14, Silvia Nardelli2, Salvatore Piano3, Chiara Elia4, Loredana Prestianni5, Federica Mirici Cappa, Lucia Cesarini, L. Simone, Chiara Pasquale2, M. Cavallin3, Alida Andrealli4, F. Fidone5, Matteo Ruggeri11, A. Roncadori, Maurizio Baldassarre1, Manuel Tufoni1, Giacomo Zaccherini1, Mauro Bernardi1, Marco Domenicali15, Ferdinando Giannone, Manuela Merli, Stefania Gioia16, Silvano Fasolato, Antonietta Sticca, Daniela Campion, A. Risso, Giorgio Maria Saracco, D. Maiorca, Agostino Rizzotto, Arianna Lanzi, Elga Neri, Anna Visani, Antonio Mastroianni, A Alberti, Chiara Mazzarelli, Marcello Vangeli, Marco Marzioni, Francesca Capretti, Alba Kostandini, G. Magini, M. Colpani, Giacomo Laffi, T Gabbani, Maria Marsico, M. Zappimbulso, Josè Petruzzi, Vincenza Calvaruso, Giovanni Parrella, Nicola Caporaso, Francesco Auriemma, Maria Guarino, Fabio Pugliese, Antonio Gasbarrini15, Pietro Leo, Francesco De Leonardis, A. Pecchioli, Piera Rossi, Giovanni Raimondo, Elisa Negri, Marcello Dallio, Carmelina Loguercio, Dario Conte16, Natascia Celli, R. Bringiotti, N.M. Castellaneta, Francesco Salerno 
TL;DR: Long-term HA administration prolongs overall survival and might act as a disease modifying treatment in patients with decompensated cirrhosis in this trial.

290 citations

Journal ArticleDOI
TL;DR: Adherence to the WCRF/AICR recommendations for cancer prevention may lower the risk of developing most types of cancer.

290 citations

Journal ArticleDOI
09 Jul 2019-JAMA
TL;DR: Treatment might be indicated for patients with sub clinical hypothyroidism and serum thyrotropin levels of 10 mU/L or higher or for young and middle-aged individuals with subclinical hypothyroxine and symptoms consistent with mild hypothy thyroid disease.
Abstract: Importance Subclinical hypothyroidism, defined as an elevated serum thyrotropin (often referred to as thyroid-stimulating hormone, or TSH) level with normal levels of free thyroxine (FT4) affects up to 10% of the adult population. Observations Subclinical hypothyroidism is most often caused by autoimmune (Hashimoto) thyroiditis. However, serum thyrotropin levels rise as people without thyroid disease age; serum thyrotropin concentrations may surpass the upper limit of the traditional reference range of 4 to 5 mU/L among elderly patients. This phenomenon has likely led to an overestimation of the true prevalence of subclinical hypothyroidism in persons older than 70 years. In patients who have circulating thyroid peroxidase antibodies, there is a greater risk of progression from subclinical to overt hypothyroidism. Subclinical hypothyroidism may be associated with an increased risk of heart failure, coronary artery disease events, and mortality from coronary heart disease. In addition, middle-aged patients with subclinical hypothyroidism may have cognitive impairment, nonspecific symptoms such as fatigue, and altered mood. In the absence of large randomized trials showing benefit from levothyroxine therapy, the rationale for treatment is based on the potential for decreasing the risk of adverse cardiovascular events and the possibility of preventing progression to overt hypothyroidism. However, levothyroxine therapy may be associated with iatrogenic thyrotoxicosis, especially in elderly patients, and there is no evidence that it is beneficial in persons aged 65 years or older. Conclusions and Relevance Subclinical hypothyroidism is common and most individuals can be observed without treatment. Treatment might be indicated for patients with subclinical hypothyroidism and serum thyrotropin levels of 10 mU/L or higher or for young and middle-aged individuals with subclinical hypothyroidism and symptoms consistent with mild hypothyroidism.

290 citations

Journal ArticleDOI
TL;DR: Assessment of the nutritional value of cherry tomato by investigating the compositional pattern of berries harvested at different ripening stages and evaluating the main antioxidants and the antioxidant activity of the water-soluble and water-insoluble fractions confirmed the relatively high level of carotenoids in cherry tomato.
Abstract: The average content of some classes of antioxidants is generally higher in cherry tomatoes than in normal-sized berries. The aim of this work was to assess the nutritional value of cherry tomato (c...

289 citations

Journal ArticleDOI
TL;DR: An extensive review of the literature is performed, searching for the following keywords: metabolism, gut microbiota, dysbiosis, obesity, to report the current knowledge on the definition, composition, and functions of intestinal microbiota.
Abstract: Nowadays, obesity is one of the most prevalent human health problems. Research from the last 30 years has clarified the role of the imbalance between energy intake and expenditure, unhealthy lifestyle, and genetic variability in the development of obesity. More recently, the composition and metabolic functions of gut microbiota have been proposed as being able to affect obesity development. Here, we will report the current knowledge on the definition, composition, and functions of intestinal microbiota. We have performed an extensive review of the literature, searching for the following keywords: metabolism, gut microbiota, dysbiosis, obesity. There is evidence for the association between gut bacteria and obesity both in infancy and in adults. There are several genetic, metabolic, and inflammatory pathophysiological mechanisms involved in the interplay between gut microbes and obesity. Microbial changes in the human gut can be considered a factor involved in obesity development in humans. The modulation of the bacterial strains in the digestive tract can help to reshape the metabolic profile in the human obese host as suggested by several data from animal and human studies. Thus, a deep revision of the evidence pertaining to the use probiotics, prebiotics, and antibiotics in obese patients is conceivable

289 citations


Authors

Showing all 29740 results

NameH-indexPapersCitations
D. M. Strom1763167194314
Yang Gao1682047146301
Robert Stone1601756167901
Elio Riboli1581136110499
Barry J. Maron15579291595
H. Eugene Stanley1541190122321
Paul Elliott153773103839
Robert O. Bonow149808114836
Kai Simons14742693178
Peter Buchholz143118192101
Martino Margoni1412059107829
H. A. Neal1411903115480
Luca Lista1402044110645
Pierluigi Paolucci1381965105050
Ari Helenius13729864789
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023234
2022660
20216,021
20205,957
20194,881
20184,267