Institution
University of Naples Federico II
Education•Naples, Campania, Italy•
About: University of Naples Federico II is a education organization based out in Naples, Campania, Italy. It is known for research contribution in the topics: Population & Cancer. The organization has 29291 authors who have published 68803 publications receiving 1920149 citations. The organization is also known as: Università degli Studi di Napoli Federico II & Naples University.
Topics: Population, Cancer, Large Hadron Collider, European Prospective Investigation into Cancer and Nutrition, Blood pressure
Papers published on a yearly basis
Papers
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TL;DR: Mucoadhesion experiments showed a rheological synergism between poloxamers/HA gels and mucin dispersion which led to a change of the flow behaviour from a quite Newtonian one of the separate solutions to a pseudoplastic one of their mixture.
239 citations
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TL;DR: There is a lack of clear information and, often, the claimed health benefits may not be properly substantiated by safety and efficacy information or in vitro and in vivo data, which can induce false expectations and miss the target for a product to be effective, as claimed.
Abstract: Currently, nutraceuticals do not have a specific definition distinct from those of other food-derived categories, such as food supplements, herbal products, pre- and probiotics, functional foods, and fortified foods. Many studies have led to an understanding of the potential mechanisms of action of pharmaceutically active components contained in food that may improve health and reduce the risk of pathological conditions while enhancing overall well-being. Nevertheless, there is a lack of clear information and, often, the claimed health benefits may not be properly substantiated by safety and efficacy information or in vitro and in vivo data, which can induce false expectations and miss the target for a product to be effective, as claimed. An officially shared and accepted definition of nutraceuticals is still missing, as nutraceuticals are mostly referred to as pharma-foods, a powerful toolbox to be used beyond the diet but before the drugs to prevent and treat pathological conditions, such as in subjects who may not yet be eligible for conventional pharmaceutical therapy. Hence, it is of utmost importance to have a proper and unequivocal definition of nutraceuticals and shared regulations. It also seems wise to assess the safety, mechanism of action and efficacy of nutraceuticals with clinical data. A growing demand exists for nutraceuticals, which seem to reside in the grey area between pharmaceuticals and food. Nonetheless, given specific legislation from different countries, nutraceuticals are experiencing challenges with safety and health claim substantiation.
239 citations
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TL;DR: Biochemical and animal studies suggest that the phloroglucinol derivative hyperforin is the main active ingredient of St John's wort, and inhibits the synaptosomal uptake of 5-HT, noradrenaline, dopamine, glutamate and GABA.
239 citations
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TL;DR: The ligand-activated transcription factor, peroxisome proliferator-activated receptor-alpha (PPAR-alpha), is identified as the receptor mediating the anti-inflammatory actions of this lipid amide.
239 citations
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TL;DR: In this paper, the authors measured the effect of jet suppression in heavy ion collisions at the LHC and provided a direct sensitivity to the physics of jet quenching, using a sample of lead-lead collisions at root S-NN = 2.76 TeV.
239 citations
Authors
Showing all 29740 results
Name | H-index | Papers | Citations |
---|---|---|---|
D. M. Strom | 176 | 3167 | 194314 |
Yang Gao | 168 | 2047 | 146301 |
Robert Stone | 160 | 1756 | 167901 |
Elio Riboli | 158 | 1136 | 110499 |
Barry J. Maron | 155 | 792 | 91595 |
H. Eugene Stanley | 154 | 1190 | 122321 |
Paul Elliott | 153 | 773 | 103839 |
Robert O. Bonow | 149 | 808 | 114836 |
Kai Simons | 147 | 426 | 93178 |
Peter Buchholz | 143 | 1181 | 92101 |
Martino Margoni | 141 | 2059 | 107829 |
H. A. Neal | 141 | 1903 | 115480 |
Luca Lista | 140 | 2044 | 110645 |
Pierluigi Paolucci | 138 | 1965 | 105050 |
Ari Helenius | 137 | 298 | 64789 |