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Institution

University of Nebraska–Lincoln

EducationLincoln, Nebraska, United States
About: University of Nebraska–Lincoln is a education organization based out in Lincoln, Nebraska, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 28059 authors who have published 61544 publications receiving 2139104 citations. The organization is also known as: Nebraska & UNL.


Papers
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Journal ArticleDOI
TL;DR: A near-complete chromosome-scale assembly for cultivated octoploid strawberry (Fragaria × ananassa) is reported and the origin and evolutionary processes that shaped this complex allopolyploid are uncovered, providing a useful resource for genome-wide analyses and molecular breeding.
Abstract: Cultivated strawberry emerged from the hybridization of two wild octoploid species, both descendants from the merger of four diploid progenitor species into a single nucleus more than 1 million years ago. Here we report a near-complete chromosome-scale assembly for cultivated octoploid strawberry (Fragaria × ananassa) and uncovered the origin and evolutionary processes that shaped this complex allopolyploid. We identified the extant relatives of each diploid progenitor species and provide support for the North American origin of octoploid strawberry. We examined the dynamics among the four subgenomes in octoploid strawberry and uncovered the presence of a single dominant subgenome with significantly greater gene content, gene expression abundance, and biased exchanges between homoeologous chromosomes, as compared with the other subgenomes. Pathway analysis showed that certain metabolomic and disease-resistance traits are largely controlled by the dominant subgenome. These findings and the reference genome should serve as a powerful platform for future evolutionary studies and enable molecular breeding in strawberry.

391 citations

Journal ArticleDOI
TL;DR: In this paper, the authors reviewed the advance in understanding the mechanisms of the ferroelectric photovoltaic effects and recent progress in improving the photiovoltaic device performance.
Abstract: The ferroelectric-photovoltaic (FE-PV) device, in which a homogeneous ferroelectric material is used as a light absorbing layer, has been investigated during the past several decades with numerous ferroelectric oxides. The FE-PV effect is distinctly different from the typical photovoltaic (PV) effect in semiconductor p–n junctions in that the polarization electric field is the driving force for the photocurrent in FE-PV devices. In addition, the anomalous photovoltaic effect, in which the voltage output along the polarization direction can be significantly larger than the bandgap of the ferroelectric materials, has been frequently observed in FE-PV devices. However, a big challenge faced by the FE-PV devices is the very low photocurrent output. The research interest in FE-PV devices has been re-spurred by the recent discovery of above-bandgap photovoltage in materials with ferroelectric domain walls, electric switchable diodes and photovoltaic effects, tip-enhanced photovoltaic effects at the nanoscale, and new low-bandgap ferroelectric materials and device design. In this feature article, we reviewed the advance in understanding the mechanisms of the ferroelectric photovoltaic effects and recent progress in improving the photovoltaic device performance, including the emerging approaches of integrating the ferroelectric materials into organic heterojunction photovoltaic devices for very high efficiency PV devices.

391 citations

Journal ArticleDOI
TL;DR: In this article, the authors evaluate spatial and temporal patterns of effective moisture variations documented by different proxies from 17 records in arid central Asia (ACA), and synthesize a decadal-resolution moisture curve for ACA over the past millennium, using 5 of the 17 records selected on the basis of reliable chronologies and robust proxies.

391 citations

Book ChapterDOI
01 Jan 2010
TL;DR: Most engineering and scientific phenomena such as the surface of a landscape or the continuously changing temperature at a location are inherently infinite in space or time or both as discussed by the authors, and it is possible to record surface elevation values or the temperature only at some specific locations and times.
Abstract: Most engineering and scientific phenomena, such as the surface of a landscape or the continuously changing temperature at a location are inherently infinite in space or time or both. We cannot measure all the data. Generally it is possible to record surface elevation values or the temperature only at some specific locations and times.

391 citations

Journal ArticleDOI
TL;DR: Improved oral bioavailability is seen in some systems where fluorine substitution leads to improved hydrolytic stability and mechanism-based inhibitors for a wide variety of diseases and to chemotherapeutic drugs.
Abstract: Fluorine substitution is a powerful tool in bioorganic and medicinal chemistry. The chemical inertness and relatively small size of fluorine 6] coupled with the short C F bond length have made C F substitution attractive for the replacement of a number of functional groups, including C OH, C H, and C=O. Fluorine incorporation into biologically active compounds can alter drug metabolism or enzyme substrate recognition. The hydrophobic nature of fluorinated compounds is also cited for improved transport across the blood± brain barrier. Improved oral bioavailability is seen in some systems where fluorine substitution leads to improved hydrolytic stability. 23±26] Furthermore, replacement of sensitive or reactive groups with fluorinated substituents has led to mechanism-based inhibitors for a wide variety of diseases and to chemotherapeutic drugs. 27±31] Review articles appear regularly on these subjects; some recent examples are given in refs. [9, 27, 32±37].

389 citations


Authors

Showing all 28272 results

NameH-indexPapersCitations
Donald P. Schneider2421622263641
Suvadeep Bose154960129071
David D'Enterria1501592116210
Aaron Dominguez1471968113224
Gregory R Snow1471704115677
J. S. Keller14498198249
Andrew Askew140149699635
Mitchell Wayne1391810108776
Kenneth Bloom1381958110129
P. de Barbaro1371657102360
Randy Ruchti1371832107846
Ia Iashvili135167699461
Yuichi Kubota133169598570
Ilya Kravchenko132136693639
Andrea Perrotta131138085669
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202393
2022381
20212,809
20202,977
20192,846
20182,854