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Institution

University of Nebraska Omaha

EducationOmaha, Nebraska, United States
About: University of Nebraska Omaha is a education organization based out in Omaha, Nebraska, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 4526 authors who have published 8905 publications receiving 213914 citations. The organization is also known as: UNO & University of Omaha.


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Journal ArticleDOI
TL;DR: Great quadriceps and GMAX activation and less hamstrings and gastrocnemius activation were correlated with smaller knee-flexion angles, and this landing strategy may predispose an individual to increased impact forces due to the negative influence on knee- flexion position.
Abstract: Context: Decreased sagittal-plane motion at the knee during dynamic tasks has been reported to increase impact forces during landing, potentially leading to knee injuries such as anterior cruciate ligament rupture. Objective: To describe the relationship between lower extremity muscle activity and knee-flexion angle during a jump-landing task. Design: Cross-sectional study. Setting: Research laboratory. Patients or Other Participants: Thirty recreationally active volunteers (15 men, 15 women: age ¼ 21.63 6 2.01 years, height ¼ 173.95 6 11.88 cm, mass ¼ 72.57 6 14.25 kg). Intervention(s): Knee-flexion angle and lower extremity muscle activity were collected during 10 trials of a jump-landing task. Main Outcome Measure(s): Simple correlation analyses were performed to determine the relationship between each knee-flexion variable (initial contact, peak, and displacement) and electromyographic amplitude of the gluteus maximus (GMAX), quadriceps (VMO and VL), hamstrings, gastrocnemius, and quadriceps : hamstring (Q : H) ratio. Separate forward stepwise multiple regressions were conducted to determine which combination of muscle activity variables predicted each knee-flexion variable. Results: During preactivation, VMO and GMAX activity and the Q : H ratio were negatively correlated with knee-flexion angle at initial contact (VMO: r ¼� 0.382, P ¼ .045; GMAX: r ¼ � 0.385, P ¼ .043; Q : H ratio: r ¼� 0.442, P ¼ .018). The VMO, VL, and GMAX deceleration values were negatively correlated with peak knee-flexion angle (VMO: r ¼� 0.687, P ¼ .001; VL: r ¼� 0.467, P ¼ .011; GMAX: r ¼� 0.386, P ¼ .043). The VMO and VL deceleration values were negatively correlated with knee-flexion displacement (VMO: r ¼� 0.631, P ¼ .001; VL: r ¼ � 0.453, P ¼ .014). The Q : H ratio and GM activity predicted 34.7% of the variance in knee-flexion angle at initial contact (P ¼ .006). The VMO activity predicted 47.1% of the variance in peak knee-flexion angle (P ¼ .001). The VMO and VL activity predicted 49.5% of the variance in knee-flexion displacement (P ¼ .001). Conclusions: Greater quadriceps and GMAX activation and less hamstrings and gastrocnemius activation were correlated with smaller knee-flexion angles. This landing strategy may predispose an individual to increased impact forces due to the negative influence on knee-flexion position.

80 citations

Journal ArticleDOI
TL;DR: A newly recovered twig with attached leaves and flowers from the Eocene Green River Formation of Utah provides the basis for recognizing a new, extinct genus of Salicaceae sensu lato (s.l.) Pseudosalix handleyi, which raises the possibility of a North American origin for the Saliceae.
Abstract: A newly recovered twig with attached leaves and flowers from the Eocene Green River Formation of Utah provides the basis for recognizing a new, extinct genus of Salicaceae sensu lato (s.l.). Pseudosalix handleyi gen. et sp. nov. has alternate lanceolate leaves with pinnate, semicraspedodromous venation and a serrate margin with glandular teeth. The inflorescence is terminal on the twig and is unisexual, composed of flowers organized in a paniculoid cyme, with lateral paraclades of pedicellate flowers. The attached pistillate flowers have four prominent sepals that are valvate in bud, spreading but basally fused at anthesis; the single pistil of each flower is ovoid with three or four longitudinal sutures, indicating development to a capsular fruit. Three or four recurved styles radiate from the apex of the pistil, each with a distal globose stigma. The infructescence, verified by attachment to twigs with the same kind of leaves, bore capsular fruits of three and four valves. Associated but unattached, staminate flowers also have four well-developed, basally connate sepals. They are pedicellate and bear several stamens, each with a short filament and globose anther. The available morphological characters place the fossil species within the Salicaceae s.l. as an immediate sister to the clade containing Populus and Salix. Although the likely outgroup genera (including Itoa, Poliothyrsis, Carrierea, and Idesia) to tribe Saliceae all occur in Asia today and not North America, the occurrence of both Pseudosalix and Populus in the Eocene of Utah raises the possibility of a North American origin for the Saliceae.

80 citations

Journal ArticleDOI
TL;DR: Reduced α‐synuclein gene expression may be important in the pathogenesis of parkinsonism and the parkinsonian phenotype may arise from haploinsufficiency at the α‐ synuclein genes at a time point before symptom onset.
Abstract: Missense mutations at the α-synuclein gene have been associated with familial parkinsonism. We report that the phenotype of a kindred (Family H) with autosomal dominant, levodopa-responsive parkinsonism maps to chromosomal region 4q21-23 and that affected members of this kindred harbor a previously reported mutation (G209A) in exon 4 of the α-synuclein gene. We assessed the expression of the G209A allele in lymphoblastoid cell lines established from 12 individuals heterozygous for the G209A allele. The expression of this allele is either absent or significantly reduced in 7 affected heterozygotes and in 3 asymptomatic heterozygotes who are older than the mean age at disease diagnosis for their generation. In contrast, it is expressed in 1 affected and 1 unaffected heterozygote. The unaffected heterozygote is younger than the mean age at disease diagnosis for their generation. The lack of or significantly reduced expression of the G209A allele in affected heterozygotes suggests that the timing of reduced expression may be critical for disease onset. If so, the parkinsonian phenotype may arise from haploinsufficiency at the α-synuclein gene at a time point before symptom onset. In condusion, reduced α-synuclein gene expression may be important in the pathogenesis of parkinsonism.

80 citations

Journal ArticleDOI
TL;DR: Neoadjuvant therapy and LT in patients with localized, node-negative disease achieves results similar to LT for other chronic liver diseases (i.e., hepatitis C virus infection, PSC) and hepatocellular carcinoma, and survival after LT in Patients with unresectable hilar C CA or hilar CCA arising in the setting of PSC exceeded survival in patients who underwent resection.

80 citations

Journal ArticleDOI
TL;DR: Using density functional theory with dispersion correction, the interfacial properties of graphdiyne that is in contact with a series of metals are studied, for the first time, in high performance nanoscale devices.
Abstract: Graphdiyne was prepared on a metal surface, and the preparation of devices using it inevitably involves its contact with metals. Using density functional theory with dispersion correction, we systematically studied, for the first time, the interfacial properties of graphdiyne that is in contact with a series of metals (Al, Ag, Cu, Au, Ir, Pt, Ni, and Pd). Graphdiyne forms an n-type Ohmic or quasi-Ohmic contact with Al, Ag, and Cu, while it forms a Schottky contact with Pd, Au, Pt, Ni, and Ir (at the source/drain-channel interface), with high Schottky barrier heights of 0.21, 0.46 (n-type), 0.30, 0.41, and 0.46 (p-type) eV, respectively. A graphdiyne field effect transistor (FET) with Al electrodes was simulated using quantum transport calculations. This device exhibits an on–off ratio up to 104 and a very large on-state current of 1.3 × 104 mA mm−1 in a 10 nm channel length. Thus, a new prospect has opened up for graphdiyne in high performance nanoscale devices.

80 citations


Authors

Showing all 4588 results

NameH-indexPapersCitations
Darell D. Bigner13081990558
Dan L. Longo12569756085
William B. Dobyns10543038956
Eamonn Martin Quigley10368539585
Howard E. Gendelman10156739460
Alexander V. Kabanov9944734519
Douglas T. Fearon9427835140
Dapeng Yu9474533613
John E. Wagner9448835586
Zbigniew K. Wszolek9357639943
Surinder K. Batra8756430653
Frank L. Graham8525539619
Jing Zhou8453337101
Manish Sharma82140733361
Peter F. Wright7725221498
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202323
2022108
2021585
2020537
2019492
2018421