University of Nebraska Omaha

About: University of Nebraska Omaha is a education organization based out in Omaha, Nebraska, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 4526 authors who have published 8905 publications receiving 213914 citations. The organization is also known as: UNO & University of Omaha.

Centered but not Caught in the Middle: Stepchildren's Perceptions of Dialectical Contradictions in the Communication of Co-Parents

Abstract: The researchers adopted a dialectical perspective to study how stepchildren experience and communicatively manage the perception of feeling caught in the middle between their parents who are living in different households. The metaphor of being caught in the middle is powerful for stepchildren and this metaphor animated their discourse. A central contribution of the present study was to understand the alternative to being caught in the middle and what this alternative means to stepchildren. Reflected in the discourse of stepchildren is that to feel not caught in the middle is to feel centered in the family. Stepchildren's desire to be centered in the family was animated by the dialectic of freedom–constraint, which co-existed within the contradictions of openness–closedness and control–restraint. These contradictions are detailed in the analysis, along with advice to parents from the perspective of stepchildren. Implications for the interaction of stepchildren and their parents are discussed.

Free Radical Theory of Aging: Effect of Dietary Fat on Central Nervous System Function*

Abstract: Free radical reactions have been implicated in aging A rise in the level of random free radical reactions in a biologic system might have a greater effect on the central nervous system (CNS) than elsewhere, partly because of the presence of glial cells and the unique connections between neurons To evaluate this possibility, some animal experiments were conducted The initial experiment involved old male Sprague-Dawley rats fed (since shortly after weaning) with semisynthetic diets characterized by fat differing in amount or degree of unsaturation The number of errors made in a Hebb-Williams maze was determined and found to be higher as the amount or degree of unsaturation of the fat was increased Likewise rats aged 6 and 9 months, fed semisynthetic diets containing 20 percent by weight of lard, oleinate, or safflower oil +alpha-tocopherol performed significantly better in a discrimination learning situation (Skinner box) than did rats fed a diet containing 20 percent by weight of safflower oil The diets employed in these studies did not have a significant effect on the mortality rates These results are compatible with the possibility that enhancing the level of lipid peroxidation has an adverse effect on the CNS, out of proportion to the effect on the body as a whole, as measured by the mortality rate

Truncated forms of the insulin-like growth factor II (IGF-II)/mannose 6-phosphate receptor encompassing the IGF-II binding site: characterization of a point mutation that abolishes IGF-II binding.

Abstract: Complete understanding of the functional significance of insulin-like growth factor II (IGF-II) binding by the IGF-II/mannose-6-phosphate (Man-6-P) receptor requires mapping and ultimately mutational analysis of the receptor's IGF-II binding domain. Recent advances have localized the IGF-II binding site to extracytoplasmic repeats 10-11. To improve resolution of the binding site map, a nested set of epitope-tagged, truncated forms of the human IGF-II/Man-6-P receptor were transiently expressed in COS-7 cells. The IGF-II binding properties of truncated receptors immunoprecipitated from cell lysates and conditioned media were determined by affinity cross-linking. From the largest truncated receptor, encompassing extracytoplasmic repeats 8-11 (M(r) 68 K), through the smallest, comprised primarily of repeat 11 (M(r) 23 K), all were able to bind and cross-link to IGF-II. As a group, the truncated receptors had similar affinities for IGF-II, but with relative binding affinities 5-to 10-fold lower than those of ...

Search and execution: examining the entrepreneurial cognitions behind the lean startup model

Abstract: The lean startup model emerging from the Silicon Valley recently has become worldwide practice. In this model, search and execution are the two primary activities conducted by entrepreneurial firms. Search activities focus on learning and discovery, such as exploring new customer and market segments, while execution activities focus on implementing well-defined plans and scaling up. Effectuation and causation are two different cognitive approaches an entrepreneur might use to conduct strategic moves. We argue that entrepreneurial effectuation cognition is associated with more search behaviors and that entrepreneurial causation cognition is associated with more execution behaviors. We test these hypotheses in a survey of 160 firms and find evidence in support of our arguments.